<human>:  Can you describe the symptoms of depression?
<bot>: Depression is a mental health condition characterized by persistent feelings of sadness, hopelessness, loss of interest in activities once enjoyed, low self-worth, and difficulty concentrating. Common symptoms may include feelings of intense sadness, irritability, exhaustion, isolation, changes in appetite, difficulty sleeping or sleeping too much, difficulty focusing, and physical aches and pains. Other signs may include withdrawing from social situations, increased anger or hostility, substance abuse, and thoughts of self-harm or suicide.