<human>:  What is the best way to defrost a piece of chicken?
<bot>: The best way to defrost a piece of chicken is to place it in the refrigerator and let it thaw overnight. If you need to thaw it quickly, you can submerge the chicken in cold water, changing the water occasionally and ensuring the water stays cold. Alternatively, you can use the microwave to thaw the chicken and cook it immediately.