<human>:  What is the prognosis for someone with end-stage pancreatic cancer?
<bot>: The prognosis for someone with end-stage pancreatic cancer is typically poor, as this is the most advanced stage of the disease and, in most cases, is associated with a significantly shorter life expectancy compared to earlier stages of the cancer. Treatment options may include palliative therapy to help manage pain, but the focus is on providing comfort and quality of life rather than a potential cure.