<human>:  What is the difference between a gene mutation and a chromosome mutation?
<bot>: A gene mutation is a change in the sequence of nucleotides in the DNA of a gene. This can be caused by a variety of factors such as radiation, chemicals, or viruses. A mutation in one gene can have a variety of effects, from causing cancer or other diseases to having no effect at all. On the other hand, a chromosome mutation is a change in the number or structure of chromosomes. This type of mutation is usually caused by irregular cell division, resulting in changes such as aneuploidy (loss or gain of entire chromosomes) or polyploidy (extra sets of chromosomes).