<human>:  Who was the first person to domesticate the water buffalo?
<bot>: The water buffalo was first domesticated in India, about 5,000 years ago. The water buffalo was the first animal to be domesticated by humans, and the only large animal to be domesticated. The first people to domesticate the water buffalo were the Indus Valley Civilization, which is a Bronze Age civilization that flourished in what is now Pakistan and northwest India.