<human>: Can you provide a brief rundown of the text in within 3 sentences?

A former bff for nearly three years [42F] at work (she was my [53F] self proclaimed 'work wife' and multiple people were convinced we were having an affair, emotional yeah, physical absolutely not) has turned super anti me in the last three.months after I grew uncomfortable with the level with the level of connection we were reaching. She's bu and showed up a day early at a place I was working to go out with me. I was a bit taken back so while it was a great time, she's married (2 years to a very straight and allegedly unaware of her attractions guy).

I transitioned (mtf) just after this trip. I was gone for a few weeks then came back feeling geat! . The bff has known I was transitioning for years. In the final weeks before my transition every conversation devolved into her crying or yelling at me. My reaction so far is pull back emotionally and personally while continuing to deal with both of them as professionally as I can muster while we're at work.

Now that I'm back at work she's adopted one of the other women [27F] in my area and is creating a very toxic situation with pretty serious slandering, gender policing, and a pretty intense campaign which seeks to assign a lot of miscommunication on myself and a few others in my department. 

While I'm a very senior person, I'm the sort of person who has good connections with people everywhere, so I am really unprepared for this kind of drama and politics. 

I value the work of both these people. I never discuss my opinion about anyone with anyone at or outside work and I basically like  everyone and would be fine with these two if they stopped this behavior. 

So, advice and insights from anyone who's dealt with anything that sounds similar is really appreciated. I'm at a loss because I've never had people go after me before.
<bot>: Should I just ignore and let them do their thing? Should I confront (not in my nature )? It's really draining me.