<human>:  What is the best way to cook a pork tenderloin?
<bot>: The best way to cook a pork tenderloin is to season it generously with salt and pepper, then roast it in the oven at 375 degrees for 25-30 minutes or until it reaches an internal temperature of 145 degrees. If desired, you can also sear it on all sides in a hot pan with a little oil first, before roasting it in the oven.