<human>:  What are the common symptoms of depression?
<bot>: The most common symptoms of depression include fatigue, changes in appetite, difficulty concentrating, feelings of guilt or worthlessness, and thoughts of suicide. 2 Other symptoms may include difficulty sleeping, restlessness, lack of interest in activities, and feelings of hopelessness. 3 Other physical symptoms such as headaches, digestive issues, and chronic pain can also be associated with depression.