<human>: My wife and I have been married for a little over a year, and we have one child together (toddler age). 

My wife has a STEM PhD. She managed to get a postdoc in our area when she finished grad school, so I didn't have to change jobs. She is super smart and works really hard, but I think her career is making her miserable. She is constantly stressed out, exhausted, and unhappy. She has trouble dealing with getting papers and grants rejected, and it makes her feel shitty and mopey for weeks every time it happens, which is all the time. Her hours are hard on me, too. Sometimes she has experiments that have to be done late at night, so I have to do all the childcare on my own after working a full day myself.

When her postdoc is over she wants to apply for faculty jobs. All of the jobs that are available are in places I would hate to live (Indiana, Iowa). We have friends here, I have a great job, and our family would be devastated if we took the baby farther away.

I know how hard my wife works and I want to be a loving and supportive husband. I don't want to be the dream-killer who tells her to give up on the academic life and do something else, but I think she would be happier in the long run if she could get a non-academic job. Plus I really, really, really don't want to move to the midwest. 

What is the best way to approach my wife about this? How can I talk to her about it without being unsupportive of her and her goals? I know the mantra here is to communicate, and I want to do exactly that, but I could use some help finding the best way to go about it.

Provide a brief overview of the text.
<bot>: My wife's job makes her miserable. I want her to find a different job but she has invested her whole life and identity in it and I don't want to be unsupportive.