<human>:  What type of activities should I do on a weekend vacation in Istanbul?
<bot>: Some activities to do on a weekend vacation in Istanbul include exploring the city's major attractions such as the Blue Mosque, Hagia Sophia, and Topkapi Palace, trying some of the local cuisine, going for a stroll along the Bosphorus, and visiting the Grand Bazaar for some shopping. You could also take a Turkish cooking class, a day tour to another city nearby, or go on a short cruise on the Bosporus.