<human>:  What are the psychological effects of long-term unemployment?
<bot>: The psychological effects of long-term unemployment can be profound and wide-ranging. It can lead to anxiety, depression, low self-esteem, decreased motivation, hopelessness, reduced quality of life and a range of physical health issues. Long-term unemployment can also put strain on family and social relationships, leading to increased isolation, loneliness and a lack of social support.