<human>: The dice were cast 40 years ago when her biological father walked out on the family of 5 kids. The psychological damage he did ruined 3 of the 5 kids right there. The other 2 (my wife and the youngest) were spared the worst of it for different reasons. 

As time went on, the alcohol, drugs, cigarettes and feelings of abondonmenment caused the children -other than my wife and the youngest- to slowly morph into angry, bitter, paranoid shadows of who they could have been. Now it's one huge ball of hatred and mistrust. My mother in law began to show signs of early dementia about 3 years ago and now she's pretty disfunctunal. They all fight over what to do with her and they're always drunk or high so nothing gets resolved. Just a bunch of fourty and fifty year-olds with no real life skills fighting.

Can you succinctly summarize the text in 1-3 sentences?
<bot>: father abandons family 40 years ago leading to a drug and alcohol-fueled dysfunctional family of in-laws. My wife is, thankfully, somehow unaffected.