text:
I'd Love to Change the World
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"I'd Love to Change the World"
Single by Ten Years After
from the album A Space in Time
B-side
"Let the Sky Fall"
Released
1971
Format
7" single
Genre
Blues rock
folk rock
psychedelic rock
Length
3:44
Label
Columbia
Songwriter(s)
Alvin Lee
Producer(s)
Chris Wright
Ten Years After singles chronology
"Love Like a Man"
(1970) "I'd Love to Change the World"
(1971) "Baby Won't You Let Me Rock 'n' Roll You"
(1972)
"Love Like a Man"
(1970) "I'd Love to Change the World"
(1971) "Baby Won't You Let Me Rock 'n' Roll You"
(1972)
"I'd Love to Change the World" is a song by the British blues rock band Ten Years After. Written by Alvin Lee, it is the lead single from the band's 1971 album A Space in Time. It is the band's only Top 40 hit, peaking at number 40 on the Billboard Hot 100 and their most popular single.[1]
Contents
[hide]
1 Background and composition
2 Release and reception
3 Personnel
4 Chart performance
5 Notes
6 References
7 External links
Background and composition[edit]
The song was written and sung by Alvin Lee.
It discusses the confused state of the world, covering a wide variety of societal complaints, until it finally addresses the Vietnam War.[1]
The song features a folk-inspired chord pattern to support the melody.[1]
Release and reception[edit]
"I'd Love to Change the World" was the band's highest charting single. It peaked at number 40 on the Billboard Hot 100 in 1971.[2] When it was released, "I'd Love to Change the World" was a staple of both FM and AM radio, a rarity for the time.[1]
Billy Walker of Sounds wrote that the "acoustic guitar, echoing vocals, and electric guitar build up the tempo with very good cool electric passages by Alvin [Lee], and while there's nothing new developing it's a very nice track".[3] Matthew Greenwald of Allmusic highlighted Lee's guitar work as the "most expressive—and most tasteful—electric guitar performance of his career", and added "if there is a single song that can describe the overall vibe of the counterculture in 1969/1970, this may very well be it. The band and Lee never quite matched the song's supple power in their later efforts, but this song is representation enough of their awesome artistry."[1]. The song is used in the trailer for the upcoming film 7 Days in Entebbe set to be released in March 2018.
Personnel[edit]
Alvin Lee – guitar and vocals
Leo Lyons – bass
Ric Lee – drums
Chick Churchill – keyboards
Chart performance[edit]
Chart (1971)
Peak
position
U.S. Billboard Hot 100[2] 40
U.S. Cash Box Top 100 Singles[4] 28
Notes[edit]
^ Jump up to: a b c d e Greenwald, Matthew. "I'd Love to Change the World review". Allmusic. Macrovision Corporation. Retrieved June 25, 2012.
^ Jump up to: a b "Ten Years After Awards". Allmusic. Macrovision Corporation. Retrieved June 25, 2012.
Jump up ^ Walker, Billy (28 August 1971). "Ten Years After Today". Sounds. Spotlight Publications. p. 6.
Jump up ^ "Cash Box Top 100 11/27/71". Cashbox Magazine, Inc. Retrieved June 25, 2012.
References[edit]
Fisher, Joseph P.; Flota, Brian (2011). The Politics of Post-9/11 Music: Sound, Trauma, and the Music Industry in the Time of Terror. Ashgate Publishing, Ltd. ISBN 1409427846.
External links[edit]
Lyrics of this song at MetroLyrics
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Reverse transcriptase
From Wikipedia, the free encyclopedia
Jump to: navigation, search
Reverse transcriptase
(RNA-dependent DNA polymerase)
Crystallographic structure of HIV-1 reverse transcriptase where the two subunits p51 and p66 are colored and the active sites of polymerase and nuclease are highlighted.[1]
Identifiers
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RVT_1
Pfam
PF00078
Pfam clan
CL0027
InterPro
IPR000477
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PS50878
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1hmv
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1hmv
CDD
cd00304
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RNA-directed DNA polymerase
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A reverse transcriptase (RT) is an enzyme used to generate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription. It is mainly associated with retroviruses. However, non-retroviruses also use RT (for example, the hepatitis B virus, a member of the Hepadnaviridae, which are dsDNA-RT viruses, while retroviruses are ssRNA viruses). RT inhibitors are widely used as antiretroviral drugs. RT activities are also associated with the replication of chromosome ends (telomerase) and some mobile genetic elements (retrotransposons).
Retroviral RT has three sequential biochemical activities:
(a) RNA-dependent DNA polymerase activity,
(b) ribonuclease H, and
(c) DNA-dependent DNA polymerase activity.
These activities are used by the retrovirus to convert single-stranded genomic RNA into double-stranded cDNA which can integrate into the host genome, potentially generating a long-term infection that can be very difficult to eradicate. The same sequence of reactions is widely used in the laboratory to convert RNA to DNA for use in molecular cloning, RNA sequencing, polymerase chain reaction (PCR), or genome analysis.
Well studied reverse transcriptases include:
HIV-1 reverse transcriptase from human immunodeficiency virus type 1 (PDB: 1HMV) has two subunits, which have respective molecular weights of 66 and 51 kDa.[2]
M-MLV reverse transcriptase from the Moloney murine leukemia virus is a single 75 kDa monomer.[3]
AMV reverse transcriptase from the avian myeloblastosis virus also has two subunits, a 63 kDa subunit and a 95 kDa subunit.[3]
Telomerase reverse transcriptase that maintains the telomeres of eukaryotic chromosomes.
Contents
[hide]
1 History
2 Function in viruses
2.1 Process of reverse transcription
2.1.1 Retroviral reverse transcription
3 In eukaryotes
4 In prokaryotes
5 Evolutionary role
6 Structure
7 Replication fidelity
8 Applications
8.1 Antiviral drugs
8.2 Molecular biology
9 See also
10 References
11 External links
History[edit]
Reverse transcriptases were discovered by Howard Temin at the University of Wisconsin–Madison in RSV virions[4] and independently isolated by David Baltimore in 1970 at MIT from two RNA tumour viruses: R-MLV and again RSV.[5] For their achievements, both shared the 1975 Nobel Prize in Physiology or Medicine (with Renato Dulbecco).
The idea of reverse transcription was very unpopular at first, as it contradicted the central dogma of molecular biology, which states that DNA is transcribed into RNA, which is then translated into proteins. However, in 1970, when the scientists Howard Temin and David Baltimore both independently discovered the enzyme responsible for reverse transcription, named reverse transcriptase, the possibility that genetic information could be passed on in this manner was finally accepted.[6]
Function in viruses[edit]
Reverse transcriptase is shown with its finger, palm, and thumb regions. The catalytic amino acids of the RNase H active site and the polymerase active site are shown in ball-and-stick form.
The enzymes are encoded and used by viruses that use reverse transcription as a step in the process of replication. Reverse-transcribing RNA viruses, such as retroviruses, use the enzyme to reverse-transcribe their RNA genomes into DNA, which is then integrated into the host genome and replicated along with it. Reverse-transcribing DNA viruses, such as the hepadnaviruses, can allow RNA to serve as a template in assembling and making DNA strands. HIV infects humans with the use of this enzyme. Without reverse transcriptase, the viral genome would not be able to incorporate into the host cell, resulting in failure to replicate.
Process of reverse transcription[edit]
Reverse transcriptase creates double-stranded DNA from an RNA template.
In virus species with reverse transcriptase lacking DNA-dependent DNA polymerase activity, creation of double-stranded DNA can possibly be done by host-encoded DNA polymerase δ, mistaking the viral DNA-RNA for a primer and synthesizing a double-stranded DNA by similar mechanism as in primer removal, where the newly synthesized DNA displaces the original RNA template.
The process of reverse transcription is extremely error-prone, and it is during this step that mutations may occur. Such mutations may cause drug resistance.
Retroviral reverse transcription[edit]
Retroviruses, also referred to as class VI ssRNA-RT viruses, are RNA reverse-transcribing viruses with a DNA intermediate. Their genomes consist of two molecules of positive-sense single-stranded RNA with a 5' cap and 3' polyadenylated tail. Examples of retroviruses include the human immunodeficiency virus (HIV) and the human T-lymphotropic virus (HTLV). Creation of double-stranded DNA occurs in the cytosol[7] as a series of these steps:
Lysyl tRNA acts as a primer and hybridizes to a complementary part of the virus RNA genome called the primer binding site or PBS.
Reverse transcriptase then adds DNA nucleotides onto the 3' end of the primer, synthesizing DNA complementary to the U5 (non-coding region) and R region (a direct repeat found at both ends of the RNA molecule) of the viral RNA.
A domain on the reverse transcriptase enzyme called RNAse H degrades the U5 and R regions on the 5’ end of the RNA.
The primer then "jumps" to the 3’ end of the viral genome, and the newly synthesised DNA strands hybridizes to the complementary R region on the RNA.
The complementary DNA (cDNA) added in (2) is further extended, and then the majority of viral RNA is degraded by RNAse H, leaving only the PP sequence.
Synthesis of the second DNA strand begins, using the remaining fragment of viral RNA as a primer.
There is then another "jump" where the PBS from the second strand hybridizes with the complementary PBS on the first strand.
Both strands are extended to form a complete double-stranded DNA copy of the original viral RNA genome, which can then be incorporated into the host's genome by the enzyme integrase.
Creation of double-stranded DNA also involves strand transfer, in which there is a translocation of short DNA product from initial RNA-dependent DNA synthesis to acceptor template regions at the other end of the genome, which are later reached and processed by the reverse transcriptase for its DNA-dependent DNA activity.[8]
Retroviral RNA is arranged in 5’ terminus to 3’ terminus. The site where the primer is annealed to viral RNA is called the primer-binding site (PBS). The RNA 5’end to the PBS site is called U5, and the RNA 3’ end to the PBS is called the leader. The tRNA primer is unwound between 14 and 22 nucleotides and forms a base-paired duplex with the viral RNA at PBS. The fact that the PBS is located near the 5’ terminus of viral RNA is unusual because reverse transcriptase synthesize DNA from 3’ end of the primer in the 5’ to 3’ direction (with respect to the RNA template). Therefore, the primer and reverse transcriptase must be relocated to 3’ end of viral RNA. In order to accomplish this reposition, multiple steps and various enzymes including DNA polymerase, ribonuclease H(RNase H) and polynucleotide unwinding are needed.[9][10]

The HIV reverse transcriptase also has ribonuclease activity that degrades the viral RNA during the synthesis of cDNA, as well as DNA-dependent DNA polymerase activity that copies the sense cDNA strand into an antisense DNA to form a double-stranded viral DNA intermediate (vDNA).[11]
In eukaryotes[edit]
Self-replicating stretches of eukaryotic genomes known as retrotransposons utilize reverse transcriptase to move from one position in the genome to another via an RNA intermediate. They are found abundantly in the genomes of plants and animals. Telomerase is another reverse transcriptase found in many eukaryotes, including humans, which carries its own RNA template; this RNA is used as a template for DNA replication.[12]
In prokaryotes[edit]
Initial reports of reverse transcriptase in prokaryotes came as far back as 1971 (Beljanski et al., 1971a, 1972). These have since been broadly described as part of bacterial Retrons, distinct sequences that code for reverse transcriptase, and are used in the synthesis of msDNA. In order to initiate synthesis of DNA, a primer is needed. In bacteria, the primer is synthesized during replication.[13]
Evolutionary role[edit]
Valerian Dolja of Oregon State argues that viruses, due to their diversity, have played an evolutionary role in the development of cellular life, with reverse transcriptase playing a central role.[14]
Structure[edit]
Reverse transcriptase enzymes include an RNA-dependent DNA polymerase and a DNA-dependent DNA polymerase, which work together to perform reverse transcription. In addition to the transcription function, retroviral reverse transcriptases have a domain belonging to the RNase H family, which is vital to their replication.
Replication fidelity[edit]
There are three different replication systems during the life cycle of a retrovirus. First of all, the reverse transcriptase synthesizes viral DNA from viral RNA, and then from newly made complementary DNA strand. The second replication process occurs when host cellular DNA polymerase replicates the integrated viral DNA. Lastly, RNA polymerase II transcribes the proviral DNA into RNA, which will be packed into virions. Therefore, mutation can occur during one or all of these replication steps.[15]
Reverse transcriptase has a high error rate when transcribing RNA into DNA since, unlike most other DNA polymerases, it has no proofreading ability. This high error rate allows mutations to accumulate at an accelerated rate relative to proofread forms of replication. The commercially available reverse transcriptases produced by Promega are quoted by their manuals as having error rates in the range of 1 in 17,000 bases for AMV and 1 in 30,000 bases for M-MLV.[16]
Other than creating single-nucleotide polymorphisms, reverse transcriptases have also been shown to be involved in processes such as transcript fusions, exon shuffling and creating artificial antisense transcripts.[17][18] It has been speculated that this template switching activity of reverse transcriptase, which can be demonstrated completely in vivo, may have been one of the causes for finding several thousand unannotated transcripts in the genomes of model organisms.[19]
Applications[edit]
The molecular structure of zidovudine (AZT), a drug used to inhibit HIV reverse transcriptase
Antiviral drugs[edit]
Further information: Reverse-transcriptase inhibitor
As HIV uses reverse transcriptase to copy its genetic material and generate new viruses (part of a retrovirus proliferation circle), specific drugs have been designed to disrupt the process and thereby suppress its growth. Collectively, these drugs are known as reverse-transcriptase inhibitors and include the nucleoside and nucleotide analogues zidovudine (trade name Retrovir), lamivudine (Epivir) and tenofovir (Viread), as well as non-nucleoside inhibitors, such as nevirapine (Viramune).
Molecular biology[edit]
Further information: Reverse transcription polymerase chain reaction
Reverse transcriptase is commonly used in research to apply the polymerase chain reaction technique to RNA in a technique called reverse transcription polymerase chain reaction (RT-PCR). The classical PCR technique can be applied only to DNA strands, but, with the help of reverse transcriptase, RNA can be transcribed into DNA, thus making PCR analysis of RNA molecules possible. Reverse transcriptase is used also to create cDNA libraries from mRNA. The commercial availability of reverse transcriptase greatly improved knowledge in the area of molecular biology, as, along with other enzymes, it allowed scientists to clone, sequence, and characterise RNA.
Reverse transcriptase has also been employed in insulin production. By inserting eukaryotic mRNA for insulin production along with reverse transcriptase into bacteria, the mRNA could be inserted into the prokaryote's genome. Large amounts of insulin can then be created, sidestepping the need to harvest pig pancreas and other such traditional sources. Directly inserting eukaryotic DNA into bacteria would not work because it carries introns, so would not translate successfully using the bacterial ribosomes. Processing in the eukaryotic cell during mRNA production removes these introns to provide a suitable template. Reverse transcriptase converted this edited RNA back into DNA so it could be incorporated in the genome.
See also[edit]
Molecular and cellular biology portal
Viruses portal
cDNA library
DNA polymerase
msDNA
Reverse transcribing virus
RNA polymerase
Telomerase
Retrotransposon marker
References[edit]
Jump up ^ PDB: 3KLF; Tu X, Das K, Han Q, Bauman JD, Clark AD, Hou X, Frenkel YV, Gaffney BL, Jones RA, Boyer PL, Hughes SH, Sarafianos SG, Arnold E (September 2010). "Structural basis of HIV-1 resistance to AZT by excision". Nat. Struct. Mol. Biol. 17 (10): 1202–9. doi:10.1038/nsmb.1908. PMC 2987654  . PMID 20852643.
Jump up ^ Ferris, AL; Hizi, A; Showalter, SD; Pichuantes, S; Babe, L; Craik, CS; Hughes, SH (April 1990). "Immunologic and proteolytic analysis of HIV-1 reverse transcriptase structure" (PDF). Virology. 175 (2): 456–64. doi:10.1016/0042-6822(90)90430-y. PMID 1691562.
^ Jump up to: a b Konishi A, Yasukawa K, Inouye K (2012). "Improving the thermal stability of avian myeloblastosis virus reverse transcriptase α-subunit by site-directed mutagenesis" (PDF). Biotechnol. Lett. 34 (7): 1209–15. doi:10.1007/s10529-012-0904-9. PMID 22426840.
Jump up ^ Temin HM, Mizutani S (June 1970). "RNA-dependent DNA polymerase in virions of Rous sarcoma virus". Nature. 226 (5252): 1211–3. doi:10.1038/2261211a0. PMID 4316301.
Jump up ^ Baltimore D. (June 1970). "RNA-dependent DNA polymerase in virions of RNA tumour viruses". Nature. 226 (5252): 1209–11. doi:10.1038/2261209a0. PMID 4316300.
Jump up ^ "Central dogma reversed". Nature. 226 (5252): 1198–9. June 1970. doi:10.1038/2261198a0. PMID 5422595.
Jump up ^ Bio-Medicine.org - Retrovirus Retrieved on 17 Feb, 2009
Jump up ^ Telesnitsky A, Goff SP (1993). "Strong-stop strand transfer during reverse transcription". In Skalka MA, Goff SP. Reverse transcriptase (1st ed.). New York: Cold Spring Harbor. p. 49. ISBN 0-87969-382-7.
Jump up ^ Bernstein A, Weiss R, Tooze J (1985). "RNA tumor viruses". Molecular Biology of Tumor Viruses (2nd ed.). Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory.
Jump up ^ Moelling, Karin; Broecker, Felix (2015). "The reverse transcriptase-RNase H: from viruses to antiviral defense". Annals of the New York Academy of Sciences. 1341 (1): 126–135. doi:10.1111/nyas.12668. ISSN 0077-8923.
Jump up ^ Doc Kaiser's Microbiology Home Page > IV. VIRUSES > F. ANIMAL VIRUS LIFE CYCLES > 3. The Life Cycle of HIV Archived 2010-07-26 at the Wayback Machine. Community College of Baltimore County. Updated: Jan 2008.
Jump up ^ Krieger M, Scott MP, Matsudaira PT, Lodish HF, Darnell JE, Zipursky L, Kaiser C, Berk A (2004). Molecular cell biology. New York: W.H. Freeman and CO. ISBN 0-7167-4366-3.
Jump up ^ Hurwitz J, Leis JP (January 1972). "RNA-dependent DNA polymerase activity of RNA tumor viruses. I. Directing influence of DNA in the reaction". J. Virol. 9 (1): 116–29. PMC 356270  . PMID 4333538.
Jump up ^ Arnold, Carrie (17 July 2014). "Could Giant Viruses Be the Origin of Life on Earth?". news.nationalgeographic.com. Retrieved 29 May 2016.
Jump up ^ Bbenek K, Kunkel AT (1993). "The fidelity of retroviral reverse transcriptases". In Skalka MA, Goff PS. Reverse transcriptase. New York: Cold Spring Harbor Laboratory Press. p. 85. ISBN 0-87969-382-7.
Jump up ^ Promega kit instruction manual (1999) Archived 2006-11-21 at the Wayback Machine.
Jump up ^ Houseley J, Tollervey D (2010). "Apparent non-canonical trans-splicing is generated by reverse transcriptase in vitro". PLoS ONE. 5 (8): e12271. doi:10.1371/journal.pone.0012271. PMC 2923612  . PMID 20805885.
Jump up ^ Zeng XC, Wang SX (June 2002). "Evidence that BmTXK beta-BmKCT cDNA from Chinese scorpion Buthus martensii Karsch is an artifact generated in the reverse transcription process". FEBS Lett. 520 (1–3): 183–4; author reply 185. doi:10.1016/S0014-5793(02)02812-0. PMID 12044895.
Jump up ^ van Bakel H, Nislow C, Blencowe BJ, Hughes TR (2011). "Response to "The Reality of Pervasive Transcription"". PLoS Biology. 9 (7): e1001102. doi:10.1371/journal.pbio.1001102.
External links[edit]
RNA Transcriptase at the US National Library of Medicine Medical Subject Headings (MeSH)
animation of reverse transcriptase action and three reverse transcriptase inhibitors
Molecule of the month (September 2002) at the RCSB PDB
HIV Replication 3D Medical Animation. (Nov 2008). Video by Boehringer Ingelheim.
Goodsell DS. "Molecule of the Month: Reverse Transcriptase (Sep 2002)". Research Collaboratory for Structural Bioinformatics (RCSB) Protein Data Bank (PDB). Retrieved 2013-01-13.
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Glucose-1,6-bisphosphate synthase
2.7.2: COOH acceptor
Phosphoglycerate
Aspartate kinase
2.7.3: N acceptor
Creatine
2.7.4: PO4 acceptor
Phosphomevalonate
Adenylate
Nucleoside-diphosphate
Uridylate
Guanylate
Thiamine-diphosphate
2.7.6: diphosphotransferase
(P2O7)
Ribose-phosphate diphosphokinase
Thiamine diphosphokinase
2.7.7: nucleotidyltransferase
(PO4-nucleoside)
Polymerase
DNA polymerase
DNA-directed DNA polymerase
I
II
III
IV
V
RNA-directed DNA polymerase
Reverse transcriptase
Telomerase
DNA nucleotidylexotransferase/Terminal deoxynucleotidyl transferase
RNA nucleotidyltransferase
RNA polymerase/DNA-directed RNA polymerase
RNA polymerase I
II
III
IV
V
Primase
RNA-dependent RNA polymerase
PNPase
Phosphorolytic
3' to 5' exoribonuclease
RNase PH
PNPase
Nucleotidyltransferase
UTP—glucose-1-phosphate uridylyltransferase
Galactose-1-phosphate uridylyltransferase
Guanylyltransferase
mRNA capping enzyme
Other
Recombinase (Integrase)
Transposase
2.7.8: miscellaneous
Phosphatidyltransferases
CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase
CDP-diacylglycerol—serine O-phosphatidyltransferase
CDP-diacylglycerol—inositol 3-phosphatidyltransferase
CDP-diacylglycerol—choline O-phosphatidyltransferase
Glycosyl-1-phosphotransferase
N-acetylglucosamine-1-phosphate transferase
2.7.10-2.7.13: protein kinase
(PO4; protein acceptor)
2.7.10: protein-tyrosine
see tyrosine kinases
2.7.11: protein-serine/threonine
see serine/threonine-specific protein kinases
2.7.12: protein-dual-specificity
see serine/threonine-specific protein kinases
2.7.13: protein-histidine
Protein-histidine pros-kinase
Protein-histidine tele-kinase
Histidine kinase
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Indian cricket team in South Africa in 2017–18
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Indian cricket team in South Africa in 2017–18
South Africa India
Dates
5 January 2018 – 24 February 2018
Captains
Faf du Plessis (Tests and ODIs)[n 1]
JP Duminy (T20Is) Virat Kohli[n 2]
Test series
Result
South Africa won the 3-match series 2–1
Most runs
AB de Villiers (211) Virat Kohli (286)
Most wickets
Vernon Philander (15)
Kagiso Rabada (15) Mohammed Shami (15)
Player of the series
Vernon Philander (SA)
One Day International series
Results
India won the 6-match series 5–1
Most runs
Hashim Amla (154) Virat Kohli (558)
Most wickets
Lungi Ngidi (8) Kuldeep Yadav (17)
Player of the series
Virat Kohli (Ind)
Twenty20 International series
Results
India won the 3-match series 2–1
Most runs
JP Duminy (122) Shikhar Dhawan (143)
Most wickets
Junior Dala (7) Bhuvneshwar Kumar (7)
Player of the series
Bhuvneshwar Kumar (Ind)
The India cricket team toured South Africa in January and February 2018[1][2] to play three Tests, six One Day Internationals (ODIs) and three Twenty20 International (T20I) matches.[3][4] In January 2017, Cricket South Africa (CSA) revealed that this tour would replace the scheduled visit by Sri Lanka due to costs and scheduling congestion.[5] The Test series was played for the Freedom Trophy, with South Africa winning the trophy following victories in the first two Tests.[6] South Africa went on to win the Test series 2–1.[7] It was the first Test series of three matches or more in which all 40 wickets fell in each match of the series.[8] With India's win the third Test, they retained the number one place in the ICC Test Championship, taking an unassailable lead before the April 2018 cut-off date for next season's rankings.[9]
In August 2017, it was announced that the traditional Boxing Day Test at Kingsmead will not take place, as India's home series against Sri Lanka will not conclude until 24 December 2017.[10] The following month it was announced that tour would likely to start on 5 January 2018.[11] CSA confirmed the fixtures in September 2017.[4][12][13] Before the Test matches, India were scheduled to play in a two-day warm-up match at Boland Park, Paarl. However, this was cancelled, as India opted to do training sessions instead of the match.[14]
The Test series marked Dale Steyn's return to international cricket. He last played in a Test match for South Africa in November 2016 against Australia in Perth, where he suffered a shoulder injury.[15] However, on day two of the first Test, Steyn damaged his left heel.[16] This ruled him out of the rest of the Test,[17] with a recovery time of 4 to 6 weeks.[18] Two days later, he was ruled out of the rest of the series.[19]
During the first ODI, South Africa's captain, Faf du Plessis, suffered a finger injury and was ruled out of the remaining ODI matches.[20] Aiden Markram was named as South Africa's captain for the remaining ODI fixtures, becoming the second-youngest South African to lead South Africa in ODIs.[21][22][23]
India ensured an ODI series victory after beating South Africa by 73 runs in the fifth match, after they had already won the first three fixtures. This resulted in India's first ODI series win in South Africa, with India maintaining their number one ranking in the ICC ODI Championship.[24][25] India went on to win the ODI series 5–1.[26] Virat Kohli scored the most runs in a bilateral ODI series by a player, with 558.[27] India were also victorious in the T20I matches, winning the series 2–1.[28]
Contents
[hide]
1 Squads
2 Test series
2.1 1st Test
2.2 2nd Test
2.3 3rd Test
3 ODI series
3.1 1st ODI
3.2 2nd ODI
3.3 3rd ODI
3.4 4th ODI
3.5 5th ODI
3.6 6th ODI
4 T20I series
4.1 1st T20I
4.2 2nd T20I
4.3 3rd T20I
5 Notes
6 References
7 External links
Squads[edit]
Tests
ODIs
T20Is
South Africa[29]
India[30]
South Africa[31]
India[32]
South Africa[33]
India[34]
Faf du Plessis (c)
Hashim Amla
Temba Bavuma
Theunis de Bruyn
Quinton de Kock (wk)
AB de Villiers
Dean Elgar
Keshav Maharaj
Aiden Markram
Morné Morkel
Chris Morris
Duanne Olivier
Lungi Ngidi
Andile Phehlukwayo
Vernon Philander
Kagiso Rabada
Dale Steyn
Virat Kohli (c)
Ajinkya Rahane (vc)
Ravichandran Ashwin
Jasprit Bumrah
Shikhar Dhawan
Ravindra Jadeja
Dinesh Karthik
Bhuvneshwar Kumar
Hardik Pandya
Parthiv Patel
Cheteshwar Pujara
K. L. Rahul
Wriddhiman Saha (wk)
Mohammed Shami
Ishant Sharma
Rohit Sharma
Murali Vijay
Umesh Yadav
Faf du Plessis (c)
Hashim Amla
Farhaan Behardien
Quinton de Kock (wk)
AB de Villiers
JP Duminy
Imran Tahir
Heinrich Klaasen
Aiden Markram
David Miller
Morné Morkel
Chris Morris
Lungi Ngidi
Andile Phehlukwayo
Kagiso Rabada
Tabraiz Shamsi
Khaya Zondo
Virat Kohli (c)
Rohit Sharma (vc)
Jasprit Bumrah
Yuzvendra Chahal
Shikhar Dhawan
MS Dhoni (wk)
Shreyas Iyer
Kedar Jadhav
Dinesh Karthik
Bhuvneshwar Kumar
Manish Pandey
Hardik Pandya
Axar Patel
Ajinkya Rahane
Mohammed Shami
Shardul Thakur
Kuldeep Yadav
JP Duminy (c)
Farhaan Behardien
Junior Dala
AB de Villiers
Reeza Hendricks
Christiaan Jonker
Heinrich Klaasen (wk)
David Miller
Chris Morris
Dane Paterson
Aaron Phangiso
Andile Phehlukwayo
Tabraiz Shamsi
JJ Smuts
Virat Kohli (c)
Rohit Sharma (vc)
Jasprit Bumrah
Yuzvendra Chahal
Shikhar Dhawan
MS Dhoni (wk)
Bhuvneshwar Kumar
Dinesh Karthik
Manish Pandey
Hardik Pandya
Axar Patel
K. L. Rahul
Suresh Raina
Shardul Thakur
Jaydev Unadkat
Kuldeep Yadav
Duanne Olivier and Lungi Ngidi were added to South Africa's squad for the second Test after Dale Steyn suffered an injury during the first Test.[35] Dinesh Karthik was called up as replacement to India's Test squad for Wriddhiman Saha after Saha was ruled out of the series due to an injury in training.[36] Temba Bavuma suffered a finger injury in a domestic one-day game and was ruled out of South Africa's squad ahead of the third and final Test.[37] South Africa's AB de Villiers was ruled out of first three ODIs due to a finger injury.[38] He was added back into South Africa's squad for the final three matches.[39]
Following the first ODI, Faf du Plessis was ruled out of South Africa's squad for the remaining ODI matches and the T20I series, after suffering a finger injury.[20] Du Plessis was replaced by Farhaan Behardien in the ODI squad and Heinrich Klaasen was added to South Africa's squad as a reserve wicket-keeper.[20][40] Aiden Markram was named as captain of South Africa for the remaining ODIs in du Plessis' absence.[21] South Africa's Quinton de Kock suffered an injury during the second ODI and was ruled out of the rest of the ODI matches and the T20I series.[41]
AB de Villiers was ruled out of South Africa's squad for the T20I series after suffering an injury before the fifth ODI match.[42]
Test series[edit]
1st Test[edit]
5–9 January 2018[n 3]
Scorecard
South Africa
v
India
286 (73.1 overs)
AB de Villiers 65 (84)
Bhuvneshwar Kumar 4/87 (19 overs)
209 (73.4 overs)
Hardik Pandya 93 (95)
Vernon Philander 3/33 (14.3 overs)
130 (41.2 overs)
AB de Villiers 35 (50)
Mohammed Shami 3/28 (12 overs)
135 (42.4 overs)
Ravichandran Ashwin 37 (53)
Vernon Philander 6/42 (15.4 overs)
South Africa won by 72 runs
Newlands Cricket Ground, Cape Town
Umpires: Michael Gough (Eng) and Richard Kettleborough (Eng)
Player of the match: Vernon Philander (SA)
South Africa won the toss and elected to bat.
No play was possible on day 3 due to rain.
Jasprit Bumrah (Ind) made his Test debut.
Wriddhiman Saha became the first wicket-keeper for India to take ten catches in a single Test.[43]
2nd Test[edit]
13–17 January 2018
Scorecard
South Africa
v
India
335 (113.5 overs)
Aiden Markram 94 (150)
Ravichandran Ashwin 4/113 (38.5 overs)
307 (92.1 overs)
Virat Kohli 153 (217)
Morné Morkel 4/60 (22.1 overs)
258 (91.3 overs)
AB de Villiers 80 (121)
Mohammed Shami 4/49 (16 overs)
151 (50.2 overs)
Rohit Sharma 47 (74)
Lungi Ngidi 6/39 (12.2 overs)
South Africa won by 135 runs
SuperSport Park, Centurion
Umpires: Michael Gough (Eng) and Paul Reiffel (Aus)
Player of the match: Lungi Ngidi (SA)
South Africa won the toss and elected to bat.
Rain and bad light ended play early on day 3.
Lungi Ngidi (SA) made his Test debut.
Mohammed Shami (Ind) took his 100th wicket in Tests.[44]
Cheteshwar Pujara became the first batsman for India to be run out in both innings of a Test.[45]
Lungi Ngidi became the 23rd bowler for South Africa to take a five-wicket haul on Test debut.[46]
3rd Test[edit]
24–28 January 2018[n 3]
Scorecard
India
v
South Africa
187 (76.4 overs)
Virat Kohli 54 (106)
Kagiso Rabada 3/39 (18.4 overs)
194 (65.5 overs)
Hashim Amla 61 (121)
Jasprit Bumrah 5/54 (18.5 overs)
247 (80.1 overs)
Ajinkya Rahane 48 (68)
Morné Morkel 3/47 (21 overs)
177 (73.3 overs)
Dean Elgar 86* (240)
Mohammed Shami 5/28 (12.3 overs)
India won by 63 runs
Wanderers Stadium, Johannesburg
Umpires: Aleem Dar (Pak) and Ian Gould (Eng)
Player of the match: Bhuvneshwar Kumar (Ind)
India won the toss and elected to bat.
Vernon Philander (SA) played in his 50th Test.[47]
Jasprit Bumrah (Ind) took his first five-wicket haul in Tests.[48]
Virat Kohli became the leading run-scorer as captain of India in Tests (3,456).[49]
Dean Elgar became the first South African to carry his bat twice in Tests since 1992.[8]
ODI series[edit]
1st ODI[edit]
1 February 2018
13:00 (D/N)
Scorecard
South Africa
269/8 (50 overs)
v
India
270/4 (45.3 overs)
Faf du Plessis 120 (112)
Kuldeep Yadav 3/34 (10 overs)
Virat Kohli 112 (119)
Andile Phehlukwayo 2/42 (8 overs)
India won by 6 wickets
Kingsmead Cricket Ground, Durban
Umpires: Ian Gould (Eng) and Bongani Jele (SA)
Player of the match: Virat Kohli (Ind)
South Africa won the toss and elected to bat.
2nd ODI[edit]
4 February 2018
10:00
Scorecard
South Africa
118 (32.2 overs)
v
India
119/1 (20.3 overs)
JP Duminy 25 (39)
Yuzvendra Chahal 5/22 (8.2 overs)
Shikhar Dhawan 51* (56)
Kagiso Rabada 1/24 (5 overs)
India won by 9 wickets
SuperSport Park, Centurion
Umpires: Aleem Dar (Pak) and Adrian Holdstock (SA)
Player of the match: Yuzvendra Chahal (Ind)
India won the toss and elected to field.
Khaya Zondo (SA) made his ODI debut.
Aiden Markram became the second-youngest player to captain South Africa in ODIs.[23]
This was South Africa's lowest total at home in ODIs.[50]
Yuzvendra Chahal (Ind) took his first five-wicket haul in ODIs.[50] His figures of 5/22 were the second-best by any spinner in South Africa after Nicky Boje's 5/21 in 2002.[51]
This was India's biggest winning margin against South Africa in ODIs, in terms of wickets (9).[52]
3rd ODI[edit]
7 February 2018
13:00 (D/N)
Scorecard
India
303/6 (50 overs)
v
South Africa
179 (40 overs)
Virat Kohli 160* (159)
JP Duminy 2/60 (10 overs)
JP Duminy 51 (67)
Kuldeep Yadav 4/23 (9 overs)
India won by 124 runs
Newlands Cricket Ground, Cape Town
Umpires: Ian Gould (Eng) and Adrian Holdstock (SA)
Player of the match: Virat Kohli (Ind)
South Africa won the toss and elected to field.
Heinrich Klaasen and Lungi Ngidi (SA) both made their ODI debuts.
Virat Kohli (Ind) scored his 34th ODI century and most as captain of India in ODIs (12).[53]
MS Dhoni became the first wicket-keeper for India to effect 400 dismissals in ODIs.[54]
This was India's biggest win, in terms of runs, against South Africa in South Africa.[55]
4th ODI[edit]
10 February 2018
13:00 (D/N)
Scorecard
India
289/7 (50 overs)
v
South Africa
207/5 (25.3 overs)
Shikhar Dhawan 109 (105)
Lungi Ngidi 2/52 (10 overs)
Heinrich Klaasen 43* (27)
Kuldeep Yadav 2/51 (6 overs)
South Africa won by 5 wickets (D/L method)
Wanderers Stadium, Johannesburg
Umpires: Aleem Dar (Pak) and Bongani Jele (SA)
Player of the match: Heinrich Klaasen (SA)
India won the toss and elected to bat.
Rain set South Africa a revised target of 202 runs from 28 overs.
Shikhar Dhawan (Ind) played in his 100th ODI and became the first batsman for India to score a century in his 100th ODI.[56][57]
5th ODI[edit]
13 February 2018
13:00 (D/N)
Scorecard
India
274/7 (50 overs)
v
South Africa
201 (42.2 overs)
Rohit Sharma 115 (126)
Lungi Ngidi 4/51 (9 overs)
Hashim Amla 71 (92)
Kuldeep Yadav 4/57 (10 overs)
India won by 73 runs
St. George's Park, Port Elizabeth
Umpires: Shaun George (SA) and Ian Gould (Eng)
Player of the match: Rohit Sharma (Ind)
South Africa won the toss and elected to field.
6th ODI[edit]
16 February 2018
13:00 (D/N)
Scorecard
South Africa
204 (46.5 oves)
v
India
206/2 (32.1 overs)
Khaya Zondo 54 (74)
Shardul Thakur 4/52 (8.5 overs)
Virat Kohli 129* (96)
Lungi Ngidi 2/54 (8 overs)
India won by 8 wickets
SuperSport Park, Centurion
Umpires: Aleem Dar (Pak) and Shaun George (SA)
Player of the match: Virat Kohli (Ind)
India won the toss and elected to field.
Virat Kohli (Ind) scored his 35th century in ODIs.[58]
Virat Kohli also became the fastest player, in terms of innings, to score 17,000 runs in international cricket (363).[59]
Virat Kohli scored the most runs in a bilateral ODI series by a player (558).[27]
T20I series[edit]
1st T20I[edit]
18 February 2018
14:30
Scorecard
India
203/5 (20 overs)
v
South Africa
175/9 (20 overs)
Shikhar Dhawan 72 (39)
Junior Dala 2/47 (4 overs)
Reeza Hendricks 70 (50)
Bhuvneshwar Kumar 5/24 (4 overs)
India won by 28 runs
Wanderers Stadium, Johannesburg
Umpires: Shaun George (SA) and Adrian Holdstock (SA)
Player of the match: Bhuvneshwar Kumar (Ind)
South Africa won the toss and elected to field.
Junior Dala and Heinrich Klaasen (SA) both made their T20I debuts.
This was India's highest total against South Africa in T20Is.[60]
Bhuvneshwar Kumar (Ind) took his first five-wicket haul in T20Is.[61]
2nd T20I[edit]
21 February 2018
18:00 (D/N)
Scorecard
India
188/4 (20 overs)
v
South Africa
189/4 (18.4 overs)
Manish Pandey 79* (48)
Junior Dala 2/28 (4 overs)
Heinrich Klaasen 69 (30)
Jaydev Unadkat 2/42 (3.4 overs)
South Africa won by 6 wickets
SuperSport Park, Centurion
Umpires: Bongani Jele (SA) and Allahudien Paleker (SA)
Player of the match: Heinrich Klaasen (SA)
South Africa won the toss and elected to field.
Shardul Thakur (Ind) made his T20I debut.
Yuzvendra Chahal conceded the most runs by an Indian bowler in a T20I.[62]
3rd T20I[edit]
24 February 2018
18:00 (D/N)
Scorecard
India
172/7 (20 overs)
v
South Africa
165/6 (20 overs)
Shikhar Dhawan 47 (40)
Junior Dala 3/35 (4 overs)
JP Duminy 55 (41)
Bhuvneshwar Kumar 2/24 (4 overs)
India won by 7 runs
Newlands Cricket Ground, Cape Town
Umpires: Shaun George (SA) and Bongani Jele (SA)
Player of the match: Suresh Raina (Ind)
South Africa won the toss and elected to field.
Christiaan Jonker (SA) made his T20I debut.
Notes[edit]
Jump up ^ Aiden Markram was named as South Africa's captain, after Faf du Plessis was injured in the first ODI.
Jump up ^ Rohit Sharma captained India for the third T20I.
^ Jump up to: a b While five days of play were scheduled for each Test, the first and third Tests reached a result within four days.
References[edit]
Jump up ^ "Sri Lanka's return visit could impact India's tour to South Africa". ESPN Cricinfo. Retrieved 29 July 2017.
Jump up ^ "Unhappy BCCI Not to Play Boxing Day Test in South Africa". News18. Retrieved 21 August 2017.
Jump up ^ "Future Tours Programme" (PDF). International Cricket Council. Retrieved 16 January 2016.
^ Jump up to: a b "CSA and BCCI announce India Tour Itinerary". Cricket South Africa. Retrieved 20 September 2017.
Jump up ^ "SA invite India for 2017-18 instead of SL". ESPN Cricinfo. Retrieved 5 January 2017.
Jump up ^ "Debutant Ngidi's 6 for 39 seals series for South Africa". ESPN Cricinfo. Retrieved 17 January 2018.
Jump up ^ "Ruthless India finish third win in South Africa". ESPN Cricinfo. Retrieved 27 January 2018.
^ Jump up to: a b "A first in Test history: 120 wickets up for grabs, 120 wickets taken". ESPN Cricinfo. Retrieved 27 January 2018.
Jump up ^ "India retain ICC Test Championship mace". International Cricket Council. Retrieved 27 January 2018.
Jump up ^ "South Africa v India: Boxing Day out, New Year likely to begin late". ESPN Cricinfo. Retrieved 19 August 2017.
Jump up ^ "South Africa-India New Year's Test likely from January 5". ESPN Cricinfo. Retrieved 18 September 2017.
Jump up ^ "Kingsmead not to host India Test". ESPN Cricinfo. Retrieved 27 September 2017.
Jump up ^ "CSA announces Zimbabwe and India tour itineraries". Cricket South Africa. Retrieved 27 September 2017.
Jump up ^ "India opt out of warm-up game ahead of SA Tests". ESPN Cricinfo. Retrieved 11 December 2017.
Jump up ^ "The late reappearance of Steyn magic". ESPN Cricinfo. Retrieved 6 January 2018.
Jump up ^ "Steyn won't bowl further in first Test, could miss rest of series". ESPN Cricinfo. Retrieved 6 January 2018.
Jump up ^ "Dale Steyn ruled out of first Test". Cricket South Africa. Retrieved 7 January 2018.
Jump up ^ "Steyn ruled out of Newlands Test, probably series". Sport24. Retrieved 6 January 2018.
Jump up ^ "Steyn sidelined for remainder of India series". ESPN Cricinfo. Retrieved 8 January 2018.
^ Jump up to: a b c "Finger injury rules Du Plessis out of India ODI and T20 Series". Cricket South Africa. Retrieved 2 February 2018.
^ Jump up to: a b "Aiden Markram to fill in as South Africa captain". ESPN Cricinfo. Retrieved 3 February 2018.
Jump up ^ "Markram appointed captain for remainder of ODI series". Cricket South Africa. Retrieved 4 February 2018.
^ Jump up to: a b "Aiden Markram to fill in as South Africa's ODI captain". ESPN Cricinfo. Retrieved 4 February 2018.
Jump up ^ "Rohit, wristspin fetch India first ODI series win in SA". ESPN Cricinfo. Retrieved 13 February 2018.
Jump up ^ "India seals number-one ODI ranking". International Cricket Council. Retrieved 13 February 2018.
Jump up ^ "Kohli's 35th ODI ton helps India wallop South Africa 5–1". ESPN Cricinfo. Retrieved 16 February 2018.
^ Jump up to: a b "Stats: Most runs by a player in a bilateral ODI series". CricTracker. Retrieved 17 February 2018.
Jump up ^ "India vs South Africa, 3rd T20, Cape Town, full cricket score: IND beat SA by 7 runs, win series 2-1". Hindustan Times. Retrieved 24 February 2018.
Jump up ^ "Du Plessis, Steyn in full-strength SA Test squad". ESPN Cricinfo. Retrieved 29 December 2017.
Jump up ^ "Bumrah earns call-up for SA Tests". ESPN Cricinfo. Retrieved 4 December 2017.
Jump up ^ "South Africa pick Ngidi and Zondo for India ODIs". ESPN Cricinfo. Retrieved 25 January 2018.
Jump up ^ "Shami, Thakur picked for India's ODIs in South Africa". ESPN Cricinfo. Retrieved 23 December 2017.
Jump up ^ "South Africa call up Jonker, Dala and Klaasen for India T20Is". International Cricket Council. Retrieved 13 February 2018.
Jump up ^ "Raina returns for SA T20s; Shreyas Iyer dropped". ESPN Cricinfo. Retrieved 28 January 2018.
Jump up ^ "Olivier, Ngidi added to South Africa squad for second Test". ESPN Cricinfo. Retrieved 8 January 2018.
Jump up ^ "Karthik to join Test squad in South Africa; Saha injured". ESPN Cricinfo. Retrieved 16 January 2018.
Jump up ^ "Bavuma fractures finger, sidelined from final India Test". ESPN Cricinfo. Retrieved 21 January 2018.
Jump up ^ "Injured de Villiers ruled out of first three ODIs". ESPN Cricinfo. Retrieved 30 January 2018.
Jump up ^ "De Villiers returns for last three ODIs". ESPN Cricinfo. Retrieved 8 February 2018.
Jump up ^ "Du Plessis out of India series with fractured finger". ESPN Cricinfo. Retrieved 2 February 2018.
Jump up ^ "De Kock ruled out of ODIs, T20s against India". ESPN Cricinfo. Retrieved 5 February 2018.
Jump up ^ "AB de Villiers ruled out of T20I series against India". ESPN Cricinfo. Retrieved 18 February 2018.
Jump up ^ "Wriddhiman Saha breaks MS Dhoni's record of most dismissals by an Indian wicketkeeper in a Test". Times of India. Retrieved 8 January 2018.
Jump up ^ "India v South Africa, 2nd Test: Mohammed Shami reaches 100 Test wickets". Times of India. Retrieved 14 January 2018.
Jump up ^ "India vs South Africa: Cheteshwar Pujara Sets Unwanted Record in Centurion Test". News18. Retrieved 17 January 2018.
Jump up ^ "Bowling records: Test matches (South Africa)". ESPN Cricinfo. Retrieved 17 January 2018.
Jump up ^ "CONGRATS! 50-up for Proteas' Philander". Sports24. Retrieved 24 January 2018.
Jump up ^ "Jasprit Bumrah makes a statement in Test cricket with maiden 5-wicket haul". India Today. Retrieved 25 January 2018.
Jump up ^ "Kohli becomes India's highest scoring Test captain". ESPN Cricinfo. Retrieved 26 January 2018.
^ Jump up to: a b "India vs South Africa: Yuzvendra Chahal's five-wicket haul leaves Sehwag in awe". India Today. Retrieved 4 February 2018.
Jump up ^ "South Africa's lowest total at home". ESPN Cricinfo. Retrieved 4 February 2018.
Jump up ^ "In Stats: Chahal, Kuldeep Run Riot as South Africa Hit Record Low". The Quint. Retrieved 4 February 2018.
Jump up ^ "Virat Kohli slams ODI century number 34; most by India captain". The Indian Express. Retrieved 7 February 2018.
Jump up ^ "India vs South Africa: MS Dhoni Becomes First Indian Wicket-keeper to Effect 400 Dismissals in ODIs". News18. Retrieved 7 February 2018.
Jump up ^ "Kohli, wristspinners trample South Africa again". ESPN Cricinfo. Retrieved 8 February 2018.
Jump up ^ "Shikhar Dhawan's 100th ODI: His top five centuries". Times of India. Retrieved 10 February 2018.
Jump up ^ "Shikhar Dhawan scores century in his 100th ODI, first Indian to do so". TimesNow. Retrieved 10 February 2018.
Jump up ^ "Virat Kohli hits 35th ODI century, 13th as captain of India". Indian Express. Retrieved 16 February 2018.
Jump up ^ "India vs South Africa: Virat Kohli quickest to 17000 international runs". India Today. Retrieved 16 February 2018.
Jump up ^ "South Africa vs India, 2018: 1st T20I – Statistical Highlights". CricTracker. Retrieved 18 February 2018.
Jump up ^ "Bhuvneshwar Kumar five-wicket haul helps India beat SA by 28 runs". India Today. Retrieved 18 February 2018.
Jump up ^ "2nd T20I Stats: Yuzvendra Chahal, Rohit Sharma create unwanted records". Sportskeeda. Retrieved 22 February 2018.
External links[edit]
Series home at ESPN Cricinfo
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values: Indische Cricket-Nationalmannschaft in Südafrika in der Saison 2017/18 – German

values: भारतीय क्रिकेट टीम का दक्षिण अफ्रीका दौरा 2018 – Hindi

values: भारतीय क्रिकेट संघाचा दक्षिण आफ्रिका दौरा, २०१८ – Marathi

values: ඉන්දියානු ක්‍රිකට් කණ්ඩායමේ දකුණු අප්‍රිකා සංචාරය 2017-2018 – Sinhala

values: இந்தியத் துடுப்பாட்ட அணியின் தென்னாப்பிரிக்க சுற்றுப்பயணம், 2018 – Tamil

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