FIGURE 3 EGFRVIII is a molecular target of WSP. (A) WSP 3D protein simulation structure by SWISS-MODEL. (B) WSP (the green part) and EGFRVIII protein (the yellow part) simulation binding site by ZDock. (C) Immunoprecipitation of EGFRVIII with His-WSP. Sgc-7901 cells were lysed with a potent cell lysate and subjected to immunoprecipitation with isotype control antibody and His label antibody and immunoprecipitated EGFRVIII protein 、 His-Tag protein were detected with western blot.CO-IP assay to verify WSP binding on EGFRVIII receptor surface. (D) Western blotting