Figure 11. Screenshot of the attached supplemental movie S3 Video in supplementary material aiming the (volume) PDE model simulation (Equations (10a)–(10d) at the cell geometry where the ER lumen is excluded). For details, cf. Section 3.3. Brief description: The RNA diffuses away from the starting ball-like region, produces NSPs at the ribosome belt, the NSPs diffuse away and bind to the pre-defined web regions (as indicated by the reconstructions) as web protein. Inside the webs, the web (bound) protein “waits” for the RNA which diffuses there. The bound web protein replicates the vRNA at the membranous web region, the RNA diffuses back to the ribosome belt and the cycle is closed and