FIGURE 6 | BIIB021 inhibited the growth of EBV-positive NK cell lymphomas in a murine xenograft model. NOD/Shi-scid/IL-2R γ null (NOG) mice were implanted subcutaneously with 1 × 10 6 SNK6 (EBV-positive NK) cells on the right flank. From days 4 to 30, DMSO (vehicle) or BIIB021 (120mg/kg) was administered orally three times per week. The tumor volume was measured twice per week. Bars indicate the SEM. * p < 0 . 05