Figure 10. Desirability contours exploring the factorial space of: ( a ) Fenofibrate to mannitol and Fenofibrate to Pharmacoat Figure 10. Desirability contours exploring the factorial space of: ( a ) Fenofibrate to mannitol and Fenofibrate to Pharmacoat Figure 10. Desirability contours exploring the factorial space of: ( a ) Fenofibrate to mannitol and Fenofibrate to Pharmacoat w / w ratios, ( b ) inlet spray drying temperature and Fenofibrate to Pharmacoat w / w ratio, and ( c ) inlet spray drying temper- w / w ratios, ( b ) inlet spray drying temperature and Fenofibrate to Pharmacoat w / w ratio, and ( c ) inlet spray drying temper- w / w ratios, ( b ) inlet spray drying temperature and Fenofibrate to Pharmacoat w / w ratio, and ( c ) inlet spray drying ature and Fenofibrate to mannitol w / w ratio. For each graph the optimum mean diameter prediction of 540.7 nm is flagged. ature and Fenofibrate to mannitol w / w ratio. For each graph the optimum mean diameter prediction of 540.7 nm is flagged. temperature and Fenofibrate to mannitol w / w ratio. For each graph the optimum mean diameter prediction of 540.7 nm is Red contours direct the most heavily populated operational route of CQA of interest. For each graph the optimum desirability Red contours direct the most heavily populated operational route of CQA of interest. For each graph the optimum desirability flagged. Red contours direct the most heavily populated operational route of CQA of interest. For each graph the optimum level is flagged. The inner rectangular shades show the variance of size of median diameter in the design space area. level is flagged. The inner rectangular shades show the variance of size of median diameter in the design space area. desirability level is flagged. The inner rectangular shades show the variance of size of median diameter in the design space