Figure 5. Exposure of HCT116 cells to VIIIc at its IC 50 (0.36 µ M) for 24 h and 48 h increased the Figure 5. Exposure of HCT116 cells to VIIIc at its IC 50 (0.36 µM) for 24 h and 48 h increased the percentage of annexin-V positive cells indicating an early (lower right quadrant) or late (upper percentage of annexin-V positive cells indicating an early (lower right quadrant) or late (upper right right quadrant) apoptosis in a time dependent manner compared to dimethylsulphoxide (DMSO) quadrant) apoptosis in a time dependent manner compared to dimethylsulphoxide (DMSO) treated treated cells. cells.