FIGURE 1 | Brain regions implicated in drug addiction. The fi gure depicts a sketch of the sagittal sections of the human (left) and mouse (right) brains. Key brain regions engaged by drug action and implicated in addiction are highlighted with different color codes. Abbreviations: Amyg, amygdala (yellow); CP, caudate putamen (purple);GP,globuspallidus(navy);Hippo,hippocampus(lightgreen);Hypo,hypothalamus(ivory);NAc,nucleusaccumbens(pink);OFC,orbitofrontalcortex(red);PFC, prefrontal cortex (blue); SN, substantia nigra (brown); VP, ventral pallidum (dark brown); VTA, ventral tegmental area (green).