Here is the design of a clinical trial:

Official Title: STRONG for Surgery & Strong for Life - Against All Odds: Intensive Prehabilitation Including Smoking, Nutrition, Alcohol and Physical Activity for Risk Reduction in Cancer Surgery

Included conditions:
- Risk Reduction
- Urological Cancer
- Surgery
- Life Style

Study Armgroups:
- {'label': 'Prehabilitation', 'type': 'EXPERIMENTAL', 'description': "Intervention: Patients allocated to the intervention group receive weekly counselling sessions in 6 weeks as an integrated prehabilitation program tailored to meet the individual patient's need for risk reduction at surgery. It is introduced via the surgical 'Engage in the process of change'. The smoking and alcohol cessation intervention follows the Gold Standard Programme and patients in the intervention group are introduced to a standardized exercise training programme taking individualized needs into account. Nutritional support is also individualized.", 'interventionNames': ['Behavioral: Prehabilitation']}
- {'label': 'Treatment as usual', 'type': 'NO_INTERVENTION', 'description': 'Treatment as ususal covers shorter interventions, e.g. advice, brief counselling, and handing out the national folders on smoking and alcohol and surgery. Patients are ensured that they are free to access support to lifestyle changes in the community.'}

Interventions:
- {'type': 'BEHAVIORAL', 'name': 'Prehabilitation', 'description': 'Patients screened positive for minimun 1 SNAP factor will be offered enrollment in the study and have an individualized plan for the prehabilitation intervention.', 'armGroupLabels': ['Prehabilitation'], 'otherNames': ['smoking cessation, alcohol cessation, physical activity, nutritional support for malnutrition and obesity']}

Primary Outcomes:
- {'measure': 'Number of patients with risk reduction at surgery', 'description': 'Corresponding at least 1 step for 1 or more risky lifestyles (but only smoking in study III) on the ASA-score (American Society of Anaesthesiologists physical status classification from 1-5, lower is better)', 'timeFrame': 'End of intervention/ at surgery'}

Please estimate the sample size based on the assumption: 
The power is set at 80% with a significance level of 2 × alpha = 0.05. The sample size also accounts for a lower effect of the intervention and allows for dropouts.
Sample size {14}
        Overall, we will include 42 patients. The power calculation regarding the main outcome is based on meta-analyses of quit rates after about 6âweeks at 70% (ranging 50â90%) [29, 30] after the intensive interventions like GSP for smoking and alcohol cessation intervention in the perioperative period as well as on studies reporting completion of physical exercise programmes at 66%, while the effect in the control groups were 15% (5â25%) [33, 57]. The corresponding lifestyle-related risk reduction will go from 100 to 30% in the intervention group and from 100 to 85% in the control group. Using an 80% power and 2 Ã alpha = 0.05, this would result in enrolment of 2 Ã 11 patients. However, the effect of obesity intervention is not known in patients with cancer undergoing major bladder surgery, but the number of patients with obesity seems low based on clinical experience; thus, a conservatively estimated sample size based on a lower effect of the intervention and allowing for dropouts would be 2 Ã 21 patients.
        The number of participants in the interviews is determined by the concept of information power which will guide the adequate sample size. This entails an ongoing reflection during the study considering issues such as the aim of the study, sample specificity, use of a theoretical background and the chosen analytical strategy [58]. In this study, we propose to include about 8 patients from the RCT study and their relatives and clinical staff.