Here is the design of a clinical trial:

Official Title: Electroacupuncture for Stress-predominant Mixed Urinary Incontinence: a Three-armed Randomized Controlled Trial

Included conditions:
- Mixed Urinary Incontinence

Study Armgroups:
- {'label': 'Electroacupuncture(EA) group', 'type': 'EXPERIMENTAL', 'description': 'Participants in EA group will receive treatment at bilateral Bladder Meridian (BL) 33 \\[Zhongliao\\], BL35 \\[Huiyang\\] and Spleen Meridian (SP) 6 \\[Sanyinjiao\\]. The EA treatment will last 30mins for each session, 3 sessions a week (ideally every other day) for a succession of 8 weeks.', 'interventionNames': ['Procedure: Electroacupuncture']}
- {'label': 'Sham Electroacupuncture (SA) group', 'type': 'SHAM_COMPARATOR', 'description': 'Participants in SA group will receive treatment at bilateral sham BL33 \\[Zhongliao\\], sham BL35 \\[Huiyang\\] and sham SP6 \\[Sanyinjiao\\]. The SA treatment will last 30mins for each session, 3 sessions a week (ideally every other day) for a succession of 8 weeks.', 'interventionNames': ['Procedure: Sham electroacupuncture']}
- {'label': 'Waiting List (WL) group', 'type': 'NO_INTERVENTION', 'description': 'Participants in WL group will be followed up for 20 weeks. Participants only receive healthcare education and advice on lifestyle modification, which will be received by all the participants in the three groups.'}

Interventions:
- {'type': 'PROCEDURE', 'name': 'Electroacupuncture', 'description': 'BL33 is located in the third posterior sacral foramen; BL35, 0.5 cun (≈10mm) lateral to the extremity of the coccyx; and SP6 posterior to the medial border of the tibia, 3 cun superior to the prominence of the medial malleolus. BL33 will be inserted by needles of 0.30×75mm size at the angle of 45°, inward and downward, till the depth of 60-70mm. BL35 will be inserted by needles of 0.30×75mm size, slightly outward and upward, till the depth of 60-70mm. SP6 will be inserted by needles of 0.30×40mm till the depth of 25-30mm. All the needles will be lifted, thrust and twisted evenly for three times, right after insertion, to induce the sensation of deqi. Electronic acupuncture apparatus (Yingdi KWD 808 I electro pulse acupuncture therapeutic apparatus, Changzhou Yingdi Electronic Medical Device Co., Ltd) will be connected to the three pairs of needles transversally, with continuous wave of 20 Hertz (Hz), electric current of 2-6.5 milliampere (mA) for BL33 and BL35, and 1mA-3.5mA for SP6.', 'armGroupLabels': ['Electroacupuncture(EA) group'], 'otherNames': ['EA']}
- {'type': 'PROCEDURE', 'name': 'Sham electroacupuncture', 'description': 'Sham BL33 is in the area of 1 cun (≈20mm) horizontally outside BL33; sham BL35, 1 cun (≈20mm) horizontally outside BL35; Sham SP6, in the middle of SP6 and tendons. The three pairs of acupoints will be inserted by needles of 0.30×40mm size to a depth of 2-3mm till the needles can stand still. No manipulations will be conducted, and the sensation of deqi will not be induced. Electronic acupuncture apparatus (Yingdi KWD 808 I electro pulse acupuncture therapeutic apparatus, Changzhou Yingdi Electronic Medical Device Co., Ltd) will be connected to the three pairs of needles transversally, with continuous wave of 20Hz and minimal electric current (ideally at a degree which participant can just percept). In about 30 seconds, the electric current will be turned down, leaving the indicator light and ticking sound on.', 'armGroupLabels': ['Sham Electroacupuncture (SA) group'], 'otherNames': ['SA']}

Primary Outcomes:
- {'measure': 'Proportion of participants with at least 50% reduction of mean 24-hour stress incontinence episode frequency (IEF) from baseline.', 'description': 'The stress IEF will be documented in 3-day voiding diary.', 'timeFrame': 'week 8'}

Please estimate the sample size based on the assumption: 
80% power, two-sided significance level of 0.05%, 10% dropouts.
Sample size
        Based on our previous study,14 15 we assume that 25% of participants in the SA group will have at least 50% reduction of mean stress IEF from baseline to week 8. To detect a difference of 23% between the EA and SA group, a sample size of 232 participants will need to provide the trial with 80% power with a two-sided significance level of 0.05% and 10% dropouts.