Here is the design of a clinical trial:

Official Title: Hands-Up Program: Protocol for a Feasibility Study of a Combined Exercise and Education Randomized Controlled Trial of a 6-week Intervention in People With a Distal Radius Fracture

Included conditions:
- Distal Radius Fracture
- Osteoporosis

Study Armgroups:
- {'label': 'Hands-Up Program', 'type': 'EXPERIMENTAL', 'description': 'Participants will be guided through a 45 minutes exercise program, set up as a group exercise class, with program modifications being made for each individual participant. In order to meet the requisite number of participants there will be approximately 4 cohorts of 10 participants. Immediately after the exercise class participants will attend a 30-minute educational session. The educational sessions will cover bone health principles, nutrition for bone health, osteoporosis practice guidelines, ways to self-monitor balance and lower extremity strength, impacts of physical activity, home hazard detection, hazards at work and in the community, postural effects on bone loading and fracture risk, and integrating physical activity in daily life. Nutritional education will emphasize the importance of calcium and vitamin D, sources of both diary and dairy free calcium, vitamin D supplements, the importance of protein, and meat and meat-free sources of protein.', 'interventionNames': ['Other: Hands-Up Program']}
- {'label': 'Standard Care', 'type': 'NO_INTERVENTION', 'description': 'The control group will receive usual care after a distal radius fracture. The standard care for a distal radius fracture will receive an assessment related to whether casting or surgery is necessary. The participant may be in a cast for 6 weeks with routine check up and x-rays to monitor the healing, at 3 months, 6 months and 12 months. The participant should receive some physical therapy related to restoring function of the hand and wrist.'}

Interventions:
- {'type': 'OTHER', 'name': 'Hands-Up Program', 'description': "In addition to the usual care, being allocated to the intervention group would require the participant to attend an exercise and education program once their cast has been removed and they've restored some strength and function in their hand and wrist. The exercise portion of the intervention will focus on strength and balance training, with aspects of managing our distal radius fracture healing as well. The education will focus on learning about risk factors for a distal radius fracture, osteoporosis, exercise for adults, nutrition for adults and falls prevention strategies.", 'armGroupLabels': ['Hands-Up Program']}

Primary Outcomes:
- {'measure': 'Feasibility of recruitment', 'description': 'Number of participants recruited in one year. Recruitment will be feasible if 74 participants are recruited within 12 months', 'timeFrame': '12 months'}
- {'measure': 'Feasibility of Retention', 'description': 'number of participants that attend the final study visit. Feasibility will be met if 75% of participants attend the final study visit.', 'timeFrame': '12 months'}
- {'measure': 'Feasibility of Adherence', 'description': 'Number of participants attending each exercise class. Feasibility will be met if the participant attends greater than 60% of the exercise classes', 'timeFrame': '12 months'}

Please estimate the sample size based on the assumption: 
Not explicitly stated, but designed to provide sufficient data for pilot study and SGBA plan.
Sample size estimation
        A total of 74 participants, 32 in the Hands-Up group and 32 in the control group, is the sample size goal. The sample size was designed based on multiple papers and criteria for pilot studies,14 15 and to provide sufficient data to pilot our disaggregated SGBA plan.16 Given the predominance of women in this population we will specifically recruit men to aim for 40% of men participants, t supporting SGBA recommendations.