Here is the design of a clinical trial:

Official Title: Randomized, Double-masking, Placebo-controlled, Multicenter Clinical Trial to Evaluate the Efficacy and Safety of Ginkgo Biloba Dropping Pills in the Treatment of Coronary Heart Disease With Stable Angina Pectoris and Depression

Included conditions:
- Stable Angina Pectoris Associated With Depression

Study Armgroups:
- {'label': 'The treatment group', 'type': 'EXPERIMENTAL', 'description': 'Ginkgo biloba dropping pills (63mg / pill), oral, 5 pills each time, three times a day,12 weeks totally. ( Continued to receive the best western medicine treatment for stable angina pectoris of coronary heart disease during the observation period.)', 'interventionNames': ['Drug: Ginkgo biloba dropping pills，best western medicine treatment']}
- {'label': 'The control group', 'type': 'PLACEBO_COMPARATOR', 'description': 'Mimetic drug of ginkgo biloba dropping pills (63mg / pill),oral, 5 pills each time, three times a day,12 weeks totally.( Continued to receive the best western medicine treatment for stable angina pectoris of coronary heart disease during the observation period.)', 'interventionNames': ['Drug: Mimetic drug of ginkgo biloba dropping pills，best western medicine treatment']}

Interventions:
- {'type': 'DRUG', 'name': 'Ginkgo biloba dropping pills，best western medicine treatment', 'description': 'oral', 'armGroupLabels': ['The treatment group']}
- {'type': 'DRUG', 'name': 'Mimetic drug of ginkgo biloba dropping pills，best western medicine treatment', 'description': 'oral', 'armGroupLabels': ['The control group']}

Primary Outcomes:
- {'measure': 'Score of Seattle Angina Questionnaire（SAQ ）', 'description': 'Score 19 items of the 5 items of the scale, and calculate the total scores of the 5 items respectively, then convert them into standard points according to the formula: standard score = (actual score of the dimension - lowest score of the dimension) / (highest score of the dimension - lowest score of the dimension) × 100. The higher the score, the better the quality of life and body function.', 'timeFrame': 'at the 0-week'}
- {'measure': 'Score of Seattle Angina Questionnaire（SAQ ）', 'description': 'Score 19 items of the 5 items of the scale, and calculate the total scores of the 5 items respectively, then convert them into standard points according to the formula: standard score = (actual score of the dimension - lowest score of the dimension) / (highest score of the dimension - lowest score of the dimension) × 100. The higher the score, the better the quality of life and body function.', 'timeFrame': 'at the 4-week'}
- {'measure': 'Score of Seattle Angina Questionnaire（SAQ ）', 'description': 'Score 19 items of the 5 items of the scale, and calculate the total scores of the 5 items respectively, then convert them into standard points according to the formula: standard score = (actual score of the dimension - lowest score of the dimension) / (highest score of the dimension - lowest score of the dimension) × 100. The higher the score, the better the quality of life and body function.', 'timeFrame': 'at the 8-week'}
- {'measure': 'Score of Seattle Angina Questionnaire（SAQ ）', 'description': 'Score 19 items of the 5 items of the scale, and calculate the total scores of the 5 items respectively, then convert them into standard points according to the formula: standard score = (actual score of the dimension - lowest score of the dimension) / (highest score of the dimension - lowest score of the dimension) × 100. The higher the score, the better the quality of life and body function.', 'timeFrame': 'at the 12-week'}
- {'measure': 'Frequency of angina pectoris related symptoms every week', 'description': 'With the help of questionnaire survey，we can judge whether there is angina pectoris，record the frequency of angina pectoris symptoms, and the frequency before treatment, during follow-up and after treatment will be compared within and between groups.', 'timeFrame': 'at the 0-week'}
- {'measure': 'Frequency of angina pectoris related symptoms every week', 'description': 'With the help of questionnaire survey，we can judge whether there is angina pectoris，record the frequency of angina pectoris symptoms, and the frequency before treatment, during follow-up and after treatment will be compared within and between groups.', 'timeFrame': 'at the 1-week'}
- {'measure': 'Frequency of angina pectoris related symptoms every week', 'description': 'With the help of questionnaire survey，we can judge whether there is angina pectoris，record the frequency of angina pectoris symptoms, and the frequency before treatment, during follow-up and after treatment will be compared within and between groups.', 'timeFrame': 'at the 2-week'}
- {'measure': 'Frequency of angina pectoris related symptoms every week', 'description': 'With the help of questionnaire survey，we can judge whether there is angina pectoris，record the frequency of angina pectoris symptoms, and the frequency before treatment, during follow-up and after treatment will be compared within and between groups.', 'timeFrame': 'at the 3-week'}
- {'measure': 'Frequency of angina pectoris related symptoms every week', 'description': 'With the help of questionnaire survey，we can judge whether there is angina pectoris，record the frequency of angina pectoris symptoms, and the frequency before treatment, during follow-up and after treatment will be compared within and between groups.', 'timeFrame': 'at the 4-week'}
- {'measure': 'Frequency of angina pectoris related symptoms every week', 'description': 'With the help of questionnaire survey，we can judge whether there is angina pectoris，record the frequency of angina pectoris symptoms, and the frequency before treatment, during follow-up and after treatment will be compared within and between groups.', 'timeFrame': 'at the 5-week'}
- {'measure': 'Frequency of angina pectoris related symptoms every week', 'description': 'With the help of questionnaire survey，we can judge whether there is angina pectoris，record the frequency of angina pectoris symptoms, and the frequency before treatment, during follow-up and after treatment will be compared within and between groups.', 'timeFrame': 'at the 6-week'}
- {'measure': 'Frequency of angina pectoris related symptoms every week', 'description': 'With the help of questionnaire survey，we can judge whether there is angina pectoris，record the frequency of angina pectoris symptoms, and the frequency before treatment, during follow-up and after treatment will be compared within and between groups.', 'timeFrame': 'at the 7-week'}
- {'measure': 'Frequency of angina pectoris related symptoms every week', 'description': 'With the help of questionnaire survey，we can judge whether there is angina pectoris，record the frequency of angina pectoris symptoms, and the frequency before treatment, during follow-up and after treatment will be compared within and between groups.', 'timeFrame': 'at the 8-week'}
- {'measure': 'Frequency of angina pectoris related symptoms every week', 'description': 'With the help of questionnaire survey，we can judge whether there is angina pectoris，record the frequency of angina pectoris symptoms, and the frequency before treatment, during follow-up and after treatment will be compared within and between groups.', 'timeFrame': 'at the 9-week'}
- {'measure': 'Frequency of angina pectoris related symptoms every week', 'description': 'With the help of questionnaire survey，we can judge whether there is angina pectoris，record the frequency of angina pectoris symptoms, and the frequency before treatment, during follow-up and after treatment will be compared within and between groups.', 'timeFrame': 'at the 10-week'}
- {'measure': 'Frequency of angina pectoris related symptoms every week', 'description': 'With the help of questionnaire survey，we can judge whether there is angina pectoris，record the frequency of angina pectoris symptoms, and the frequency before treatment, during follow-up and after treatment will be compared within and between groups.', 'timeFrame': 'at the 11-week'}
- {'measure': 'Frequency of angina pectoris related symptoms every week', 'description': 'With the help of questionnaire survey，we can judge whether there is angina pectoris，record the frequency of angina pectoris symptoms, and the frequency before treatment, during follow-up and after treatment will be compared within and between groups.', 'timeFrame': 'at the 12-week'}

Please estimate the sample size based on the assumption: 
Significance level (α) of 0.05, power (β) of 0.8, and a potential dropout rate of 10%
Sample size calculation
        To the best of our knowledge, there are no previous studies on treating SAP with depressive symptoms in CHD with GBDPs. As suggested in previous studies on GBDPs and similar proprietary Chinese medicines for CHD,20â22 the sample size was estimated, and the improvement of weekly angina attack frequency was taken as the main effect index according to the statistical requirements. We assumed the mean difference of 2.7, with a pooled SD of 3.8 for each group, Î±=0.05 (the significant level), and Î²=0.2 (power of 0.8), the sample size in the test and control groups will be estimated to be 32 (1:1 sample size ratio) for 64 cases. In addition, a potential dropout rate of 10% will be considered, requiring a sample of 72 cases.