Here is the design of a clinical trial:

Official Title: NUTS for the Prevention of Cardiovascular Disease in Chinese Adults : a Randomized Controlled Trial (NUTS)

Included conditions:
- Cardiovascular Diseases
- Dyslipidemias

Study Armgroups:
- {'label': 'Low-dose group', 'type': 'EXPERIMENTAL', 'description': 'Low-dose group will received 30 grams of walnuts everyday during the study period of 6 months.', 'interventionNames': ['Dietary Supplement: Walnuts 30 grams']}
- {'label': 'High-dose group', 'type': 'EXPERIMENTAL', 'description': 'High-dose group will received 60 grams of walnuts everyday during the study period of 6 months.', 'interventionNames': ['Dietary Supplement: Walnuts 60 grams']}
- {'label': 'Control group', 'type': 'NO_INTERVENTION', 'description': 'Control group will received non-edible gifts during the study period of 6 months.'}

Interventions:
- {'type': 'DIETARY_SUPPLEMENT', 'name': 'Walnuts 30 grams', 'description': 'Roasted walnuts without salt or sugar.', 'armGroupLabels': ['Low-dose group']}
- {'type': 'DIETARY_SUPPLEMENT', 'name': 'Walnuts 60 grams', 'description': 'Roasted walnuts without salt or sugar.', 'armGroupLabels': ['High-dose group']}

Primary Outcomes:
- {'measure': 'Post-intervention differences in blood plasma alpha linolenic acid between groups', 'description': 'Blood plasma alpha linolenic acid will be measured at baseline and 6 months (end of trial).', 'timeFrame': 'From baseline to 6 months'}

Please estimate the sample size based on the assumption: 
Two-sided alpha of 0.05, 90% power, standard deviation of 0.18, 10% drop-out rate
Sample size
        The sample size of 210 individuals (70 in each arm) provided more than 90% power with two-sided alpha of 0.05 to detect a mean difference of 0.12% (as percent of total fatty acid) in plasma ALA between the 30âg walnut supplementation and control arms [10]. The power estimation assumed a standard deviation (SD) of 0.18 and allowed for a drop-out rate of 10%. The study had similar power to detect a mean difference of 0.12% in plasma ALA comparing the 60âg/day and 30âg/day walnut supplementation groups. The power estimations were conservative since the assumptions were based on the PREDIMED trial that provided lower doses of walnuts (15âg/day) than the doses employed in this trial [10].