Here is the design of a clinical trial:

Official Title: Quick-Wee Versus Bladder Stimulation to Collect Midstream Urine From Pre-continent Infants: a Randomized Controlled Trial

Included conditions:
- Urinary Tract Infections

Study Armgroups:
- {'label': 'bladder stimulation', 'type': 'EXPERIMENTAL', 'interventionNames': ['Other: bladder stimulation']}
- {'label': 'Quick wee', 'type': 'ACTIVE_COMPARATOR', 'interventionNames': ['Other: Quick wee']}

Interventions:
- {'type': 'OTHER', 'name': 'bladder stimulation', 'description': 'The bladder stimulation technique requires the presence of 2 people:\n\n* The child must be held by an adult (caregiver or parent) under the armpits, legs dangling.\n* the first person (the investigator), performs the stimulation technique consisting of: rapid tapping (frequency of about 100 / min), over the pubic area, at the level of the bladder, alternated with external rotational movements of the pits lumbar, in the kidneys. Alternate these 2 maneuvers every 30 seconds.\n* The second person starts the stopwatch at the start of the stimulation, and is about to collect the urine, 2nd jet in a sterile pot\n* The maneuver ends as soon as urine is obtained, and will be stopped after 5 minutes in case of failure.', 'armGroupLabels': ['bladder stimulation']}
- {'type': 'OTHER', 'name': 'Quick wee', 'description': 'The Quick wee technique requires the presence of only one person:\n\nStimulation of the suprapubic area by circular movements, with a cold and wet compress held by sterile forceps.\n\nCollection of urine in a sterile container.', 'armGroupLabels': ['Quick wee']}

Primary Outcomes:
- {'measure': 'volume of urine collection to measure the effectiveness of two techniques', 'description': 'measure of success of the urine collection technique is determined by collecting at least 2 millimeters of urine in less than 5 minutes', 'timeFrame': 'at the end of intervention completion, an average 30 minutes'}

Please estimate the sample size based on the assumption: 
A bilateral hypothesis with an alpha risk of 5%, power of 80%, and an additional 10% to account for data loss.
Sample size
        Based on the literature data,24 the success rate for midstream urine collection by Quick-Wee is 31% in infants under 1 year of age. The success rate for midstream urine collection by bladder stimulation is 56%.22 Therefore, we plan to have a success rate of 50% in the Bladder Stimulation group.
        Thus, the number of subjects per arm required to demonstrate this difference between the groups with a ÏÂ² test would be 104 according to a bilateral hypothesis, at the alpha risk of 5% and with a power of 80% (nQuery Advisor, V.7.0). We consider an additional 10% of patients to account for data loss. Therefore, a sample size of 230 infants under the age of 1 year will be included in the study (115 in each group).
        According to our estimates, 250 patients per year who meet the inclusion criteria consult in the emergency departments of the investigating centres. Considering a participation rate of around 60%, 150 infants are eligible per year. It seems reasonable to consider a study period of 18 months.