Here is the design of a clinical trial:

Official Title: Long-term Effects of Visual Spatial Working Memory Training Program Performed at Preschool Age in Very Preterm Infants With Visual Spatial Working Memory Deficit. A Randomized Controlled Trial

Included conditions:
- Children Born Extremely Premature
- Disturbance of Visuo-spatial Working Memory

Study Armgroups:
- {'label': 'Cognitive remediation parents', 'type': 'ACTIVE_COMPARATOR', 'interventionNames': ['Other: computerized cognitive remediation program']}
- {'label': 'Remediation standard', 'type': 'PLACEBO_COMPARATOR', 'interventionNames': ['Other: standard remediation']}

Interventions:
- {'type': 'OTHER', 'name': 'computerized cognitive remediation program', 'description': 'a computer program online re-educating the working memory is completed by the parents and the child. The child made a series of interactive exercises accompanied by parents or a practitioner. The exercises are adapted automatically and individually to the performance at each session.', 'armGroupLabels': ['Cognitive remediation parents']}
- {'type': 'OTHER', 'name': 'standard remediation', 'description': 'A speech therapy and / or academic support is realized.', 'armGroupLabels': ['Remediation standard']}

Primary Outcomes:
- {'measure': 'Increase of the measuring index visuospatial', 'description': 'This index consists of two subtests : block design and object assembly. The average score is 100 with a standard deviation of 15.', 'timeFrame': '18 months (more or less 2 months) post inclusion'}

Please estimate the sample size based on the assumption: 
The study assumes an 80% power, a significance level of 0.05, and a 15% dropout rate.
Sample size
        The sample size was calculated to obtain an 80% power to detect a difference of 7.5 points on the VSI index (estimated standard deviation: 15) at 18âmonths (+/ââ2âmonths) between the two groups. This has been considered to be clinically significant considering other similar studies [5]. With the threshold for statistical significance set at a p-value of 0.05, assuming that a potential 15% of patients will be lost to follow-up between baseline and last assessments, these calculations showed that 166 patients are needed (83 per group [Power Analysis and Sample Size Software Version 2008, Utah, USA]). Assuming that 30â40% of the EPIPAGE 2 children will present with a WM abnormality, 1600 children will be required for screening.