Here is the design of a clinical trial:

Official Title: Goal-directed Mobilization of Medical Inpatients (GoMob-in) - a Randomized, Controlled Trial

Included conditions:
- Immobility Syndrome
- Fall
- Delirium
- Sarcopenia
- Mobility Limitation
- Hospital Acquired Condition

Study Armgroups:
- {'label': 'GDM', 'type': 'EXPERIMENTAL', 'description': 'Goal-directed mobilization', 'interventionNames': ['Behavioral: Goal-directed mobilization']}
- {'label': 'Control', 'type': 'NO_INTERVENTION', 'description': 'Standard of care'}

Interventions:
- {'type': 'BEHAVIORAL', 'name': 'Goal-directed mobilization', 'description': '* A short educational intervention with handout of a leaflet on GDM.\n* Definition of personal mobility goal level.\n* Communication of the mobility goal level to involved stakeholders.\n* Regular reassessment of the mobility goal level and "booster sessions" by physiotherapists.', 'armGroupLabels': ['GDM']}

Primary Outcomes:
- {'measure': 'Change from baseline of the DEMMI score', 'description': 'Change of the de Morton Mobility Index (DEMMI) score (range 0 to 100 with 0 indicating poor physical activity and 100 indicating a high level of independent physical activity) from baseline (at study inclusion), assessed by independent, blinded physiotherapist', 'timeFrame': 'Day 5±2'}

Please estimate the sample size based on the assumption: 
Two-sided alpha level of 0.05, power of 0.8, and an estimated drop-out rate of 20%.
Estimated sample size and power
        The sample size calculation was based on the primary outcome of a clinically meaningful change in the DEMMI score between baseline and 5âdays of follow-up. The DEMMI score ranges from 0 to 100 points with 0 indicating no physical activity and 100 indicating maximal physical activity. Based on previous studies on changes in DEMMI scores during short-term hospitalisation of roughly 10 days,26 27 we expect a difference in change between the two groups of 5 score points. In an observational study of participants with low and high activity, SD for changes in the DEMMI score was 7.8 and 8.5 points, respectively (personal communication).26 In a study on older adult inpatients, the SD was between 12.5 and 15.4 points for absolute DEMMI scores at admission and discharge, respectively.27 The SD for changes is typically smaller than for absolute values; we therefore expect a rather conservative SD of about 10 points for the change in our study.
        To detect a difference in change of 5 score points with a SD of 10 points, at a two-sided alpha level of 0.05 with a power of 0.8, a sample size of 2Ã64 participants is required. Based on an estimated drop-out rate of 20%, we aim to include 160âpatients into the study (80 in each group).