Here is the design of a clinical trial:

Official Title: The Feasibility of Fingerprick Autologous Blood (FAB) As a Novel Treatment for Severe Dry Eye Disease (DED)

Included conditions:
- Dry Eye Syndromes

Study Armgroups:
- {'label': 'FAB group', 'type': 'ACTIVE_COMPARATOR', 'description': 'Arm A - Finger prick autologous blood (FAB) plus conventional treatment The patients will use FAB alongside conventional therapy as recommended by their treating ophthalmologist. A fingertip of the hand will be wiped with an alcohol steret and self-pricked using a standard diabetic lancet. The drop of blood is produced as normal and applied to the lower fornix of the affected eye(s) with the lower lid pulled down slightly by the patient. The blood will be applied 4 times a day. A fresh finger should be used for each eye. FAB should be applied at least 15 minutes after any artificial tears and no other drops applied for at least half an hour afterwards', 'interventionNames': ['Other: Fingerprick autologuos blood (FAB)']}
- {'label': 'Control group', 'type': 'NO_INTERVENTION', 'description': 'Arm B - Conventional treatment only The patients will use conventional therapy (artificial tears, cyclosporin drops and punctal plugs/cautery) as recommended by their treating ophthalmologist'}

Interventions:
- {'type': 'OTHER', 'name': 'Fingerprick autologuos blood (FAB)', 'description': 'Intervention involves the instillation of whole blood obtained from the prick of a clean finger 4 times a day.', 'armGroupLabels': ['FAB group'], 'otherNames': ['FAB']}

Primary Outcomes:
- {'measure': 'Number of patients recruited into the study within the specified time frame', 'description': 'This will involve specifically assessing the number of eligible patient in study population consented and randomized.', 'timeFrame': '12 months'}
- {'measure': 'Number of patients who adhere to trial protocol', 'description': 'Measured by self-reported adherence to trial protocol', 'timeFrame': '12months'}

Please estimate the sample size based on the assumption: 
The study aims to estimate parameters such as the standard deviation for a subsequent full-scale trial. A conservative attrition rate of 10% is assumed.
Sample size
        As this is a feasibility trial, there were no formal sample size calculations.23 The aim of the study is to recruit aÂ sufficient number of patients to evaluate the acceptability and feasibility of the intervention. An outcome of this study will be to estimate parameters such as the SD for a sample size calculation of a subsequent full-scale trial. A sample of 52 patients (26 in each arm) is considered adequate for obtaining reliable sample size estimates.24 25 To allow for a conservative attrition rate of 10%, we aim to recruit 60 patients into the trial.