Here is the design of a clinical trial:

Official Title: HEalth-Related Quality of Life-intervention in Survivors of Breast and Other Cancers Experiencing Cancer-related Fatigue Using TraditionAL Chinese Medicine: The HERBAL Trial

Included conditions:
- Cancer
- Fatigue
- Cognitive Impairment

Study Armgroups:
- {'label': 'XBYRT decoction', 'type': 'EXPERIMENTAL', 'description': 'Participants assigned to receive the modifed Xiang Bei Yang Rong Tang granules', 'interventionNames': ['Other: Modified Xiang Bei Yang Rong Tang']}
- {'label': 'Placebo', 'type': 'PLACEBO_COMPARATOR', 'description': 'Participants assigned to receive placebo (contains 5% of XBYRT) granules', 'interventionNames': ['Other: Placebo']}

Interventions:
- {'type': 'OTHER', 'name': 'Modified Xiang Bei Yang Rong Tang', 'description': 'Modified Xiang Bei Yang Rong Tang is a combination of 15 herbal components and it is available in granules form to be dissolved in hot water for consumption', 'armGroupLabels': ['XBYRT decoction']}
- {'type': 'OTHER', 'name': 'Placebo', 'description': 'Placebo granules contain 5% XBYRT, colourant, bitterant and 95% starch filler', 'armGroupLabels': ['Placebo']}

Primary Outcomes:
- {'measure': 'Difference in Global Health Status (GHS) score', 'description': 'Difference in Global Health Status (GHS) score from the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) between XBYRT interventional and placebo arms from baseline to 8 weeks after baseline. The GHS scale ranges in score from 0-100. A higher score represents a better quality of life', 'timeFrame': '8 weeks from baseline'}

Please estimate the sample size based on the assumption: 
10% dropout rate.
Sample size
        In order to ensure that the sample size is adequately powered to estimate a reliable standard deviation (SD) for a phase III trial, Teare et al. has recommended to include at least 70 subjects (35 per arm) for estimating the SD for a continuous outcome [31]. Therefore, to account for a 10% dropout, a total sample size of 80 patients (rounded up from 78), with 40 participants on each arm, is required for this study.