Here is the design of a clinical trial:

Official Title: TREatment of Triangular FibrOcaRtilage ComplEx Ruptures (REINFORCER): Protocol for Randomized, Controlled, Blinded, Efficacy Trial of Triangular Fibrocartilage Complex Tears

Included conditions:
- Triangular Fibrocartilage Complex Injury

Study Armgroups:
- {'label': 'Central or Radial Tear: Arthroscopic debridement', 'type': 'EXPERIMENTAL', 'description': 'Arthroscopic debridement', 'interventionNames': ['Procedure: Arthroscopic Debridement']}
- {'label': 'Central or Radial Tear: Sham surgery', 'type': 'PLACEBO_COMPARATOR', 'description': 'Diagnostic arthroscopy only (placebo surgery).', 'interventionNames': ['Procedure: Placebo surgery']}
- {'label': 'Ulnar Tear: Arthroscopic or open repair', 'type': 'EXPERIMENTAL', 'description': 'Arthroscopic or open repair', 'interventionNames': ['Procedure: Arthroscopic or Open Repair']}
- {'label': 'Ulnar Tear: Physiotherapy', 'type': 'ACTIVE_COMPARATOR', 'description': 'Diagnostic arthroscopy and physiotherapy', 'interventionNames': ['Procedure: Physiotherapy']}

Interventions:
- {'type': 'PROCEDURE', 'name': 'Arthroscopic Debridement', 'description': 'Wrist arthroscopy can be performed with or without irrigation. In the debridement arm, a central or radial TFCC tear found during arthroscopy is debrided with a shaver. Portals are closed either with sutures or with medical tape. Immediate mobilization of the wrist is allowed after the operation. Participants are provided with instructions for home exercises, and they are advised to commence the exercises two weeks post-operation.', 'armGroupLabels': ['Central or Radial Tear: Arthroscopic debridement']}
- {'type': 'PROCEDURE', 'name': 'Placebo surgery', 'description': 'Diagnostic wrist arthroscopy can be performed with or without irrigation. A central or radial TFCC tear found during wrist arthroscopy is left untouched and no other operative interventions are done. Portals are closed either with sutures or with medical tape. The procedure is performed in general or regional anesthesia in operating room. Participants are not able to see to the operation area or monitor. They will listen to music with noise-cancelling headphones throughout the operation. The operative time will be matched, with the surgeon simulating a debridement procedure. Immediate mobilization of the wrist is allowed after the operation. Participants are provided with instructions for home exercises, and they are advised to commence the exercises two weeks post-operation.', 'armGroupLabels': ['Central or Radial Tear: Sham surgery']}
- {'type': 'PROCEDURE', 'name': 'Arthroscopic or Open Repair', 'description': 'An ulnar TFCC tear found during wrist arthroscopy is sutured to the capsule or fovea with one of the separately defined methods choosed by the treating hand surgeon. The procedure is performed in general or regional anesthesia in operating room. Wounds are closed and standardized post-operative treatment is started after six weeks.', 'armGroupLabels': ['Ulnar Tear: Arthroscopic or open repair']}
- {'type': 'PROCEDURE', 'name': 'Physiotherapy', 'description': 'An ulnar TFCC tear found during wrist arthroscopy is left untouched and no other operative interventions are done. Portals are closed with sutures or medical tape. The procedure is performed in general or regional anesthesia in operating room. Physiotherapy exercises of wrist and DRUJ stabilizers is started after two weeks.', 'armGroupLabels': ['Ulnar Tear: Physiotherapy']}

Primary Outcomes:
- {'measure': 'Patient-Rated Wrist Evaluation (PRWE)', 'description': 'The PRWE questionnaire is a wrist-specific instrument comprising a 15-item questionnaire assessing pain and disability in daily living. PRWE provides a score ranging from 0 (best) to 100 (worst). This wrist-specific tool demonstrates good reliability, validity, and responsiveness. Translation and validation have been conducted for Danish, Finnish, and Swedish languages. In interpreting the results, we will employ the Minimally Important Difference (MID) value of 14. PRWE as secondary outcome will be measured at all the other time points (6 months, 2, 5 and 10 years) than primary outcome.', 'timeFrame': '10 year follow-up, primary time point at 1 year'}

Please estimate the sample size based on the assumption: 
Type I error rate (significance level) is 0.05, power is 80%, and attrition rate is 15%.
Sample size
        This trial is designed as a superiority trial, aiming to detect a mean difference of 14 points. With type I error rate of 0.05 and a power of 80%, we need 44 participants per arm to detect a difference of >14 points in PRWE assuming SD of 20. Considering attrition rate of 15%, the final number of participants per randomisation cohort arm is 51, totalling 204 participants for the whole trial.