Here is the design of a clinical trial:

Official Title: Movement and Health Beyond Care, MoviS: Nutrition and Exercise Educational Programs for Breast Cancer Survivors

Included conditions:
- Breast Cancer Survivors

Study Armgroups:
- {'label': 'Interventional Arm', 'type': 'EXPERIMENTAL', 'description': 'Supervised exercise program: MoviS Training. Lifestyle (nutrition and exercise) counseling based on WCRF 2018 recommendations; psychological well-being counseling which comprises evaluation for anxiety and depression.', 'interventionNames': ['Behavioral: MoviS Training']}
- {'label': 'Control Arm', 'type': 'NO_INTERVENTION', 'description': 'Lifestyle (nutrition and exercise) counseling based on WCRF 2018 recommendations; psychological well-being counseling which comprises evaluation for anxiety and depression.'}

Interventions:
- {'type': 'BEHAVIORAL', 'name': 'MoviS Training', 'description': 'Patients will undergo a supervised exercise program consisting of 3 months of aerobic exercise training (2 d/week of directly supervised exercise and 1 d/week of remotely supervised exercise) with a progressive increase in exercise intensity (40-70% of heart rate reserve) and duration (20-60 min).', 'armGroupLabels': ['Interventional Arm']}

Primary Outcomes:
- {'measure': 'Quality of life assessed by questionnaire', 'description': 'Change in quality of life assessed by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30). Scores ranging from 0 to 100; higher scores indicate better quality of life.', 'timeFrame': 'Baseline - after 3, 6, 12, 24 months'}

Please estimate the sample size based on the assumption: 
Using a t-test for independent samples, with an alpha of 0.05 and statistical power of 0.80, and considering an expected drop-out rate of 30%.
Sample size {14}
        The sample size was calculated with the aim of verifying the differences between the QoL changes in the two groups (i.e., intervention and control arm), after 3 months of intervention.
        The QoL expected improvement in the experimental group at 12 weeks is 15.1 Â± 17.7, while in the control arm, it is 6.1 Â± 17.1 [24]. Using a t-test for independent samples, with an alpha of 0.05 and statistical power of 0.80, to find differences in QoL improvements between the two groups at the end of the intervention, 60 participants per group will be needed. Considering an expected drop-out of 30%, a total of 172 patients will be recruited. The sample size was calculated using Stata statistical software (StataCorp. 2013. Stata Statistical Software: Release 13. College Station, TX: StataCorp LP).