Here is the design of a clinical trial:

Official Title: Simultaneous Portal and Hepatic Vein Embolization Versus Portal Vein Embolization for Hypertrophy of the Future Liver Remnant Before Major Hepatectomy of Non-cirrhotic Liver : a Multicentric Comparative Randomized Phase II Trial

Included conditions:
- Liver Metastasis Colon Cancer

Study Armgroups:
- {'label': 'portal vein embolization', 'type': 'ACTIVE_COMPARATOR', 'description': 'Liver preparation before major hepatectomy : portal vein embolization (PVE) in patient with liver metastases from colo-rectal origin considered as resectable.', 'interventionNames': ['Procedure: Liver preparation before major hepatectomy']}
- {'label': 'liver venous deprivation', 'type': 'EXPERIMENTAL', 'description': 'Liver preparation before major hepatectomy : Patients with the liver venous deprivation (LVD) technique that combines both PVE and hepatic vein embolization (HVE) during the same procedure.', 'interventionNames': ['Procedure: Liver preparation before major hepatectomy']}

Interventions:
- {'type': 'PROCEDURE', 'name': 'Liver preparation before major hepatectomy', 'description': 'Simultaneous portal and hepatic vein embolization versus Portal vein embolization, also called venous deprivation OR portal vein embolization.', 'armGroupLabels': ['liver venous deprivation', 'portal vein embolization']}

Primary Outcomes:
- {'measure': 'increase in volume of the future remnant liver (FRL)', 'description': 'The primary outcomes is to compare the increase in volume of the future remnant liver (FRL)', 'timeFrame': 'at 3 weeks after liver venous deprivation (LVD) or portal vein embolization (PVE) using MRI or CT-scan'}

Please estimate the sample size based on the assumption: 
Standard deviation of 14% in each arm, two-sided α = 5%, power of 90%, and a 5% dropout rate.
Sample size and follow-up period
        Our hypotheses for sample size calculation are based on a systematic review on PVE before liver resection, involving 1791 patients [9]: the mean increase of the FLR volume was 37.9% at 26âdays. In our preliminary study [5] and in a more recent paper by Le Roy et al. [10], a mean increase of 53% of the FLR volume was observed after 3âweeks. Therefore, it is realistic to expect a difference of 12% (or more) between the 2 procedures at 21âdays. With a standard deviation of 14% in each arm, a two-sided Î±â=â5% and a power of 90%, according to a Student Test, 30 patients have to be randomized by arm. Taking into account that 5% of the patients could not be evaluable, 32 patients have to be randomized per arm. Finally, planned enrollment will be 64 subjects. The expected duration of the recruitment of all patients is 24âmonths with a minimal duration of the subject participation of 5âmonths.