Here is the design of a clinical trial:

Official Title: Strength Training as a Supplemental Therapy of Androgen Deficiency of the Aging Male (ADAM)

Included conditions:
- Hypogonadism, Male
- Physical Activity
- Testosterone Deficiency

Study Armgroups:
- {'label': 'hypogonadal males without TRT', 'type': 'EXPERIMENTAL', 'description': 'Strength training', 'interventionNames': ['Procedure: Strength training']}
- {'label': 'hypogonadal males with TRT', 'type': 'EXPERIMENTAL', 'description': 'Strength training and regular prescribed testosterone therapy given by participant urologist.', 'interventionNames': ['Procedure: Strength training']}
- {'label': 'healthy eugonadal males', 'type': 'ACTIVE_COMPARATOR', 'description': 'Strength training', 'interventionNames': ['Procedure: Strength training']}

Interventions:
- {'type': 'PROCEDURE', 'name': 'Strength training', 'description': 'The participants perform strength training sessions two times per week for 12 weeks. Each training session include 5-minute general dynamic warm-up followed by progressive strength training with exercises for the entire body. The strength exercises are performed with free weights and on machines. The training program consist of 6 exercises for upper and lower body at an intensity of 60-80% (8 - 12RM: the load that induces technique failure in eight or twelve repetitions) of one-repetition maximum and takes approximately 60 minutes. The exercises performed are: leg press, split squats, bench press, knee extension, knee flexion, seated cable rows, seated cable pull downs, dumbbell bench press, incline dumbbell bench press.', 'armGroupLabels': ['healthy eugonadal males', 'hypogonadal males with TRT', 'hypogonadal males without TRT']}

Primary Outcomes:
- {'measure': 'Change From Baseline in Lean Mass', 'description': 'Total body by Dual-energy X-ray Absorptiometry using Hologic fan-beam bone densitometer Discovery QDR series.', 'timeFrame': '7 days before intervention, 7 days after intervention'}

Please estimate the sample size based on the assumption: 
Type I error probability of 0.05, power of 0.90 and 0.95, 10% dropout rate
Sample size
        The pre-existing data from our previous 12 week exercise intervention study related to fat (5.6% decrease p=0.002) & lean body mass (1.8% increase, p=0.047, dual-energy X-ray absorptiometry) and that of maximal voluntary contraction force measured on linear leg-press (31% increase, p<0.0001, 1RM). Lean body mass was used to determine sample size for the population of the designed intervention study. The Type I error probability was set at 0.05 and the power to 0.90 and 0.95. Results indicate that 22 patients per group will be sufficient to detect exercise intervention related change of 1,06Â±1,56 kg (average Â±SD) of lean body mass at the power of 0.90, accounting for the 10% patients drop-out.