Here is the design of a clinical trial:

Official Title: Efficacy of Laser Acupuncture for Carpal Tunnel Syndrome

Included conditions:
- Carpal Tunnel Syndrome

Study Armgroups:
- {'label': 'Six-sessions of laser acupuncture', 'type': 'EXPERIMENTAL', 'description': 'Laser acupuncture was given three times a week for 2 weeks.', 'interventionNames': ['Device: laser phototherapy device with low level laser']}
- {'label': 'Six-sessions of sham laser acupuncture', 'type': 'SHAM_COMPARATOR', 'description': 'Sham laser acupuncture was given three times a week for 2 weeks.', 'interventionNames': ['Device: laser phototherapy device with low level laser']}

Interventions:
- {'type': 'DEVICE', 'name': 'laser phototherapy device with low level laser', 'description': 'The wavelength of low level laser is 808nm and the power output of low level laser is 300mW.', 'armGroupLabels': ['Six-sessions of laser acupuncture', 'Six-sessions of sham laser acupuncture']}

Primary Outcomes:
- {'measure': 'Change from baseline of severity of symptoms and functional status on 2th, 4th, 8th and 12th weeks after treatment by using Boston Carpal Tunnel Questionnaire (BCTQ).', 'description': 'The Boston Carpal Tunnel Questionnaire (BCTQ) is a disease-specific measure of self-reported symptom severity and functional status. One is the minimum score and five is the maximum score in each symptom severity scale (11 items). The total score range of symptom severity scale is 11 to 55. One is the minimum score and five is the maximum score in each functional status scale (8 items). The total score range of functional status scale is 8 to 40.\n\nUsing the Boston Carpal Tunnel Questionnaire to measure the symptoms and functional status of carpal tunnel syndrome before treatment and multiple time frame after treatment.', 'timeFrame': 'baseline, 2th, 4th, 8th and 12th weeks after treatment'}

Please estimate the sample size based on the assumption: 
Power of 80% (1 - β = 0.8), statistical significance (α = 0.05) of 95%, and a dropout rate of 20%.
2.4.1
          Sample size
          The necessary number of subjects required for our study is based on a previous study of the effects of LLLT for CTS.[22] The sample size was calculated with a power of 80% (1 â Î²â=â0.8), statistical significance (Î±â=â0.05) of 95% and a dropout rate of 20%. As a result, this study will require at least 40 wrists.