Here is the design of a clinical trial:

Official Title: Evaluation of Videolaryngoscopy (McGrath Mac) Compared to Direct Laryngoscopy for Rapid Sequence Intubation in Operating Room

Included conditions:
- Pulmonary Aspiration of Gastric Contents

Study Armgroups:
- {'label': 'McGrath MAC', 'type': 'EXPERIMENTAL', 'description': 'First pass success rate using the McGrath Mac', 'interventionNames': ['Device: McGrath Mac']}
- {'label': 'Macintosh Laryngoscope', 'type': 'EXPERIMENTAL', 'description': 'First pass success rate using the Macintosh laryngoscope', 'interventionNames': ['Device: Macintosh Laryngoscope']}

Interventions:
- {'type': 'DEVICE', 'name': 'McGrath Mac', 'description': 'in a randomized order we evaluate the first pass success rate of the tracheal tube into the trachea.', 'armGroupLabels': ['McGrath MAC']}
- {'type': 'DEVICE', 'name': 'Macintosh Laryngoscope', 'description': 'in a randomized order we evaluate the first pass success rate of the tracheal tube into the trachea.', 'armGroupLabels': ['Macintosh Laryngoscope']}

Primary Outcomes:
- {'measure': 'First pass Intubation success rate', 'description': 'successful tracheal intubation at the first attempt, compared to more than one attempt', 'timeFrame': 'at intubation in 60 seconds'}

Please estimate the sample size based on the assumption: 
The study assumes a power of 96% and a significance level of 5%, with a drop-out rate of about 5%.
Sample size
        The sample size calculation was based on achieving successful tracheal intubation on the first attempt. In recent trials, the VL showed a first attempt success rate of 97%. We determined the power of the study by assuming a first-pass success rate of 92% (DL)20 30 and 97% (McG).43 We chose this study for the sample size calculation because the purpose was to compare VL and DL, including anaesthesia trainees in the operating room. On the basis of the current first-pass success rate, we hypothesised that an increase of 5% by skilled laryngoscopists in the McGrath group compared with the DL group would be a relevant improvement in airway management. We determined that the inclusion of 474âpatients per group would show relevant differences. Assuming a drop-out rate of about 5%, 500âpatients per group will be included. With 1000âpatients, an increase from 92% (DL) to 97% (McG) in the first-pass success rate can be observed with a power of 96% at the 5% significance level.