Here is the design of a clinical trial:

Official Title: Body and Brain: Effects of a Multicomponent Exercise Intervention on Physical and Cognitive Function of Older Adults With Dementia

Included conditions:
- Dementia
- Alzheimer Disease
- Vascular Dementia
- Neurocognitive Disorders

Study Armgroups:
- {'label': 'Experimental Group', 'type': 'EXPERIMENTAL', 'description': 'Training protocol will be held for 6 months, twice per week/ 60 min per sessions.', 'interventionNames': ['Other: Exercise']}
- {'label': 'Control Group', 'type': 'NO_INTERVENTION', 'description': 'Participants in the control group will receive monthly sessions regarding physical activity and health related topics as a complement to standard care. No specific exercise intervention will be conducted for this group.'}

Interventions:
- {'type': 'OTHER', 'name': 'Exercise', 'description': 'The MT program will be conducted for 6 months, twice a week in 60 minutes sessions. Sessions will be divided in warm-up (10 minutes, including slow walk, postural and mobility exercises for general activation, and stretching exercises), specific training (35-45 minutes, including balance/coordination training, strength and aerobic exercises) and cool down (5 minutes with breathing and stretching exercises for the main worked joints and muscles) following the main guidelines recommended by the American College of Sports Medicine \\[18\\] and the WHO \\[19\\].', 'armGroupLabels': ['Experimental Group'], 'otherNames': ['Multicomponent training']}

Primary Outcomes:
- {'measure': 'Change from Baseline on Short Physical Performance Battery (SPBB)', 'description': 'The Short Physical Performance Battery (SPPB) is a standardised assessment tool of lower limb function, testing 3 dimensions: standing balance, walking speed, and chair stands. Each component is scored between 0-4, total score from 0 (poor performance) to 12 (best performance).', 'timeFrame': 'Assessment at baseline, immediately after 6 months of intervention, and at 3 months follow-up for experimental and control groups'}
- {'measure': "Change from Baseline on Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog)", 'description': 'To evaluate cognitive function with a total scoring ranging between 0 - 68. A score of 68 represents the most severe impairment and 0 represents the least impairment.', 'timeFrame': 'Assessment at baseline, immediately after 6 months of intervention, and at 3 months follow-up for experimental and control groups'}

Please estimate the sample size based on the assumption: 
80% power, alpha level of 0.05, estimated dropout of 25%
Sample size
          Sample size was estimated based on ANCOVA for the analysis of the differences [41]. To detect an adjusted 1 point (SDâ=â2.1) difference in SPPB after intervention between IG and CG with 80% power and an alpha level of 0.05, a total of 110 participants (55 participants per group) will be needed, already accounting for an estimated dropout of 25%. Sample size calculation was performed using G*Power 3.1.3 (UniversitÃ¤t DÃ¼sseldorf, DÃ¼sseldorf, Germany) [42].