Here is the design of a clinical trial:

Official Title: Assessment of Remifentanil for Rapid Sequence Induction and Intubation in Full Stomach Patient Compared to Muscle Relaxant. A Non-inferiority Simple Blind Randomized Controlled Trial

Included conditions:
- Intra-tracheal Intubation

Study Armgroups:
- {'label': 'Remifentanil group', 'type': 'EXPERIMENTAL', 'description': 'bolus intravenous injection of 3 to 4µg/kg of remifentanil after hypnotic administration for a crush anesthetic induction', 'interventionNames': ['Drug: Remifentanil group']}
- {'label': 'Neuromuscular blockade group', 'type': 'ACTIVE_COMPARATOR', 'description': 'Bolus intravenous injection of 1mg/kg of Succinylcholine or Rocuronium after hypnotic administration for a crush anesthetic induction', 'interventionNames': ['Drug: neuromuscular blockade group']}

Interventions:
- {'type': 'DRUG', 'name': 'Remifentanil group', 'description': 'bolus intravenous injection of 3 to 4µg/kg of remifentanil after hypnotic administration for a crush anesthetic induction', 'armGroupLabels': ['Remifentanil group']}
- {'type': 'DRUG', 'name': 'neuromuscular blockade group', 'description': 'Bolus intravenous injection of 1mg/kg of Succinylcholine or Rocuronium after hypnotic administration for a crush anesthetic induction', 'armGroupLabels': ['Neuromuscular blockade group']}

Primary Outcomes:
- {'measure': 'Rate of tracheal intubation without major complication', 'description': 'Primary endpoint is the rate of tracheal intubation without major complications as defined by\n\n1. tracheal intubation with less than 2 laryngoscopies\n2. no aspiration during the 10 minutes after induction\n3. no desaturation under 95% during the 10 minutes after induction\n4. no hypo or hypertension as defined by a MAP\\<50mmHg or \\>110mmHg\n5. no ventricular arrhythmia involving an emergency treatment or cardiac arrest during the 10 minutes after induction\n6. no grade III or IV anaphylactic reaction during the 10 minutes after induction', 'timeFrame': 'Day 7 from randomization'}

Please estimate the sample size based on the assumption: 
Statistical power of 80%, alpha risk of 2.5%.
Sample size
        The proportion of successful tracheal intubation without any major complications is the primary outcome. In previous studies, the proportion of rapid sequence induction of general anesthesia with a rapid-onset paralytic agent without major complications ranged between 70 and 92%, depending on the studies and definitions [19â21]. It is also recommended to set non-inferiority margins lower than a 10% relative difference between the intervention and control groups [22]. Assuming an 80% rate of tracheal intubation without major complication in the rapid-onset paralytic agent group, and given the potential benefit of avoiding the use of rapid paralytic agents, we deemed it medically acceptable to set the non-inferiority margin to an absolute difference of 7% (8.75% relative difference). We thus calculated that a total of 1150 patients (575 patients per group) was needed to demonstrate the non-inferiority of the intervention with a statistical power of 80% an alpha risk of 2.5.