Here is the design of a clinical trial:

Official Title: Cupping Therapy in the Treatment of Individuals With Nonspecific Chronic Low Back Pain

Included conditions:
- Low Back Pain

Study Armgroups:
- {'label': 'Cupping therapy with 2 suctions', 'type': 'EXPERIMENTAL', 'description': 'Participants in the intervention group will receive the application of cupping therapy with two acrylic type 1 cups with a distance of 3 cm each cup, parallel to the L1 to L5 vertebrae bilaterally. This group will consist of the application of windsheets with 2 suctions for 10 minutes, once a week, for 10 weeks. The cups shall be secured by means of elastic bands.', 'interventionNames': ['Other: Cupping Therapy']}
- {'label': 'Cupping Therapy sham', 'type': 'PLACEBO_COMPARATOR', 'description': 'The placebo group will receive the application of cupping therapy with 2 cups of acrylic type size 1 with a distance of 3 cm each cup, parallel to the vertebrae L1 to L5, bilaterally . This group will consist of applying the sham winds for 10 minutes, once a week for 10 weeks.\n\nHowever, the cups will be made with small holes \\<2 mm in diameter to release the negative pressure in seconds. The cups will also be fixed by means of elastic bands.', 'interventionNames': ['Other: Cupping Therapy']}

Interventions:
- {'type': 'OTHER', 'name': 'Cupping Therapy', 'description': 'application of cupping therapy with two acrylic type 1 cups (4.5 cm internal diameter, Dong Yang ® brand) with a distance of 3 cm each cup, parallel to the L1 to L5 vertebrae bilaterally', 'armGroupLabels': ['Cupping Therapy sham', 'Cupping therapy with 2 suctions']}

Primary Outcomes:
- {'measure': 'Change from Numeric Rating Scale (NRS) of Pain', 'description': "The patients are asked to circle the number between 0 and 10. Zero usually represents 'no pain at all' whereas the upper limit represents 'the worst pain ever possible'", 'timeFrame': 'T0 -baseline, T4 (four week) and T8 (eight week)'}

Please estimate the sample size based on the assumption: 
Statistical power of 90%, alpha of 5%, and a loss rate of 10%.
âSample size calculation
        Based on study values using similar methods,65 a total sample of 90 participants (45 in IG and 45 in PG) will be sufficient to detect a clinically important difference between the two-point groups on the NPRS scale. A statistical power of 90% and an alpha of 5% and a loss rate of 10% were considered for the sample calculation. Gpower 3 software was used for the calculation.