Here is the design of a clinical trial:

Official Title: Electroacupuncture vs Topical Diclofenac Sodium Gel for Patients With Hand Osteoarthritis: Study Protocol for a Randomized Controlled Trial

Included conditions:
- Hand Osteoarthritis

Study Armgroups:
- {'label': 'Electroacupuncture group', 'type': 'EXPERIMENTAL', 'interventionNames': ['Other: Electroacupuncture']}
- {'label': 'Topical DSG group', 'type': 'ACTIVE_COMPARATOR', 'interventionNames': ['Drug: Topical diclofenac sodium gel']}

Interventions:
- {'type': 'OTHER', 'name': 'Electroacupuncture', 'description': 'We will apply Ashi points, Ex-UE9, SI3, and TE5. Sterile needles (0.3mm× 40mm) and SDZ-V EA apparatus will be utilized. Acupuncturists will insert needles perpendicularly into Ashi points for approximately 2-3mm until they pierce into the bone surface; acupuncturists will insert needles horizontally into Baxie points towards the wrist with a depth of 5-10mm; and acupuncturists will insert needles perpendicularly into SI3 and TE5 for approximately 5-10mm. All needles except Ashi points will be manually manipulated to achieve De qi. The needles at Baxie 1 and Baxie 4 will be connected using alligator clips from the EA apparatus. The electrical stimulation will last for 30 minutes with a continuous wave of 10 Hz and a fixed current intensity of 0.5 to 2 mA. All the needles will be retained for 30 minutes. Participants will undergo EA treatment three times per week for a total of 12 sessions in four consecutive weeks. If bilateral hands were affected, both sides will be treated.', 'armGroupLabels': ['Electroacupuncture group']}
- {'type': 'DRUG', 'name': 'Topical diclofenac sodium gel', 'description': 'The gel will be gently rubbed over the affected joints without excessive joint movement four times per day for 4 weeks and will be asked not to wash hands for one hour after application. Each hand treatment will be used in identical dispensing doses of gel (4 cm strip, approximately 2g, which was judged sufficient for approximately half the surface of each hand (200 cm2)). Dosing times should be distributed evenly over waking hours.If bilateral hands were affected, both sides will be treated.', 'armGroupLabels': ['Topical DSG group']}

Primary Outcomes:
- {'measure': 'Change in average overall finger joints pain intensity in the dominant hand over the past 48h from baseline to week 4', 'description': 'Pain intensity will be measured using a 0-100 VAS, with 0 indicating no pain and 100 indicating maximal pain.', 'timeFrame': 'at baseline and week 4'}

Please estimate the sample size based on the assumption: 
Two-tailed test, 5% significance level, 80% power, and a 10% dropout rate.
Sample size calculation
          This trial hypothesizes that 4Â weeks of EA treatment will be superior to topical DSG in terms of pain relief in the dominant hand for patients with hand OA. Based on the results of a previous study [15], the OA pain intensity in the dominant hand on the 0â100 VAS scale was reduced by an average of 31.1 points in the topical DSG group and 23.9 points in the vehicle group. We predict that EA will display superiority over topical DSG by at least a 7-point better relative reduction in VAS score with a standard deviation of 12. Assuming a two-tailed test with a possible drop-out of 10% of the patients, a total of 108 patients (54 in the EA group and 54 in the topical DSG group) will be required for 80% power on a 5% alpha level.