Here is the design of a clinical trial:

Official Title: Clinical Study on the Effect of Comprehensive Rehabilitation Program Plus Chemotherapy Versus Chemotherapy on Quality of Life in Postoperative Non Small Cell Lung Cancer Patients With Stage IB-IIIA

Included conditions:
- Non-small Cell Lung Cancer

Study Armgroups:
- {'label': 'Chemotherapy+Training+TCM', 'type': 'EXPERIMENTAL', 'description': 'Adjuvant Chemotherapy is performed within 6 weeks after operation. Rehabilitation training is mainly composed of gymnastic qigong, which will be started in one month after operation.\n\nPrescriptions formulated into granules origin from Professor Xu Ling in Yueyang hospital. Package of granules is made into four types with functions such as benefiting Qi recipe, benefiting Yin recipe, harmonizing stomach recipe, detoxication and resolving masses recipe. Patients will take harmonizing stomach recipe granules for the first week after chemotherapy and syndrome differentiation granules in TCM for second weeks from the end of chemotherapy. The patient will take TCM granules for 3 months.', 'interventionNames': ['Behavioral: Rehabilitation Training', 'Drug: TCM']}
- {'label': 'Chemotherapy+Education+TCM', 'type': 'EXPERIMENTAL', 'description': 'Adjuvant Chemotherapy is performed within 6 weeks after operation. Patients who received rehabilitation education will not accept rehabilitation training.\n\nPrescriptions formulated into granules origin from Professor Xu Ling in Yueyang hospital. Package of granules is made into four types with functions such as benefiting Qi recipe, benefiting Yin recipe, harmonizing stomach recipe, detoxication and resolving masses recipe. Patients will take harmonizing stomach recipe granules for the first week after chemotherapy and syndrome differentiation granules in TCM for second weeks from the end of chemotherapy. The patient will take TCM granules for 3 months.', 'interventionNames': ['Drug: TCM', 'Other: Rehabilitation Education']}
- {'label': 'Chemotherapy+Education+Placebo', 'type': 'PLACEBO_COMPARATOR', 'description': 'Adjuvant Chemotherapy is performed within 6 weeks after operation. Patients who received rehabilitation education will not accept rehabilitation training.\n\nPatients who received rehabilitation education will not accept rehabilitation training.\n\nWe compromise the raw materials for the placebo including food color and artificial flavors. The placebo and therapeutic packages were stored in different cabinets, and only the dispensing technician knew the contents of the packages. The patient will take placebo granules for 3 months.', 'interventionNames': ['Other: Rehabilitation Education', 'Drug: placebo']}

Interventions:
- {'type': 'BEHAVIORAL', 'name': 'Rehabilitation Training', 'description': 'Patients will be trained in one month after operation. Rehabilitation training will be carried out between every two cycles of chemotherapy. Rehabilitation training is mainly composed of gymnastics qigong, which has long been regarded as a form of rehabilitation in Traditonal Chinese Medicine. According to the poor pulmonary function of patients with lung cancer after operation, Liu Zi Jue lung exercise is chosen to strengthen the pulmonary function of the human body in Chinese traditional health culture. Liu Zi Jue lung exercise intervention will be lead by an expert instructor, five times a week, 15 min/time.', 'armGroupLabels': ['Chemotherapy+Training+TCM'], 'otherNames': ['gymnastics qigong', 'Liu Zi Jue lung exercises']}
- {'type': 'DRUG', 'name': 'TCM', 'description': 'four types with functions such as benefiting Qi recipe, benefiting Yin recipe, harmonizing stomach recipe and detoxication and resolving masses recipe. Each package contained 20g of water-soluble herbal granules that were manufactured at a Good Manufacture Practice standard facility (Tian Jiang Ltd, Jiangyin, China). Each package was labeled with a serial number. The prescription form comprised the stock list with both the name and serial number.', 'armGroupLabels': ['Chemotherapy+Education+TCM', 'Chemotherapy+Training+TCM'], 'otherNames': ['Prescriptions from Professor Xu Ling']}
- {'type': 'OTHER', 'name': 'Rehabilitation Education', 'description': 'General health education', 'armGroupLabels': ['Chemotherapy+Education+Placebo', 'Chemotherapy+Education+TCM'], 'otherNames': ['health education']}
- {'type': 'DRUG', 'name': 'placebo', 'description': 'four types with functions such as benefiting Qi recipe, benefiting Yin recipe, harmonizing stomach recipe and detoxication and resolving masses recipe，with the same color, smell，taste, weight and package', 'armGroupLabels': ['Chemotherapy+Education+Placebo'], 'otherNames': ['control']}

Primary Outcomes:
- {'measure': 'Change from baseline in Quality of life (QOL)', 'description': 'QOL is assessed using European Organization for Research and Treatment of Cancer Quality of Life QuestionnaireLung Cancer 43 (EORTC QLQ-LC43).', 'timeFrame': 'Time Frame: baseline, at 4 months'}

Please estimate the sample size based on the assumption: 
Significance level (α) = 0.05, Power (1 - β) = 0.90, and a 20% dropout rate.
Sample size calculation
        The primary outcome of the study will be the change in the QoL score assessed by the QLQ-C30 scale. According to the results of the JRB.10 study, 27% of lung cancer patients at stage IbâIIIa after 3âmonths of adjuvant chemotherapy had lower QoL scores than at baseline [9]. Based on the validity assumptions and clinical experience of the past, it is estimated that 15% of patients had no deterioration in the QoL combined with a comprehensive rehabilitation program compared with treatment without a comprehensive rehabilitation program for patients receiving 3-month postoperative adjuvant chemotherapy. At an inspection level of Î±â=â0.05 and 1Â âÂ Î²â=â0.90, the QoL score after 3âmonths decreased by 10% in the intervention group and by 27% in the control group compared with baseline. A sample size of 98 patients was obtained for each group, and a 20% cutoff rate was considered; therefore, 354 patients (nâ=â118) will be observed in 3âyears. It is suggested that comprehensive rehabilitation combined with chemotherapy can improve the QoL of NSCLC postoperative patients compared with chemotherapy alone.