Here is the design of a clinical trial:

Official Title: Survival and Quality of Life After Early Surgical Intervention Versus Wait-and-see in Elderly Patients With a Traumatic Acute Subdural Hematoma (ASDH): a Pragmatic Randomized Controlled Trial With Multicenter Parallel Group Design

Included conditions:
- Intracranial Hemorrhages
- Surgery

Study Armgroups:
- {'label': 'Early surgery', 'type': 'OTHER', 'interventionNames': ['Other: Early neurosurgical hematoma evacuation']}
- {'label': 'Initial conservative treatment', 'type': 'OTHER', 'interventionNames': ['Other: Conservative treatment (best medical management)']}

Interventions:
- {'type': 'OTHER', 'name': 'Early neurosurgical hematoma evacuation', 'description': 'Early neurosurgical hematoma evacuation (preferably within 2 hours)', 'armGroupLabels': ['Early surgery']}
- {'type': 'OTHER', 'name': 'Conservative treatment (best medical management)', 'description': 'Conservative treatment (best medical management) on the ICU or ward', 'armGroupLabels': ['Initial conservative treatment']}

Primary Outcomes:
- {'measure': 'Glasgow Outcome Scale Extended (GOS-E)', 'description': 'scale of functional outcome ranging from 1-8 in which a higher score reflects a better recovery', 'timeFrame': '1 year'}

Please estimate the sample size based on the assumption: 
The sample size calculation achieves a 90% power to detect a change in the log odds ratio of 0.69 with a 0.05 (two-sided) significance level, allowing for a loss of follow-up of 8%.
Sample size {14}
        The sample size of 300 patients was based on an ordinal analysis method of the primary outcome. It was calculated analytically using PASS software version 11 and achieves a 90% power to detect a change in the log odds ratio of 0.69 with a 0.05 (two-sided) significance level, allowing for a loss of follow-up of 8%. Calculations were based on the expected percentage distribution of conservatively treated patients over the GOS-E categories 1â8 (15, 10, 10, 10, 10, 10, 15, 20) with category 1 and 2 combined and an estimated (adjusted) proportional odds ratio of 2.0 representing the targeted treatment effect that is considered clinically relevant in the management of elderly with a traumatic ASDH. Table 4 shows the corresponding distribution of patients over the GOS-E outcome categories. The rationale for combining GOS-E categories 1 and 2 in the statistical analysis is the opinion of the researchers that a potentially large shift of patients from category 1 (death) to category 2 (vegetative state) should not result in a positive trial as this cannot be considered a beneficial or positive effect of surgery.
Table 4Estimated shift over GOS-E outcome categoriesGOS-E1&2345678Patientâs conditionDead and vegetative stateLower severe disabilityUpper severe disabilityLower moderate disabilityUpper moderate disabilityLower good recoveryUpper good recoveryInitial conservative treatment (%)25101010101520Early surgery (%)14789101933