Here is the design of a clinical trial:

Official Title: The Effect of Low-level Light Therapy on Treatment of Venous Ulcers Assessed by Nursing Outcomes Classification (NOC): Randomized Clinical Trial

Included conditions:
- Venous Ulcer
- Low-Level Light Therapy

Study Armgroups:
- {'label': 'Intervention', 'type': 'EXPERIMENTAL', 'description': 'Low-level Light Therapy: Wavelength of 660 nm (red laser) and Conventional treatment: Topical treatment with compressive therapy, exercises of lower extremities, resting; once a week for 16 weeks.', 'interventionNames': ['Procedure: Low-level Light Therapy', 'Combination Product: Conventional treatment']}
- {'label': 'Controls', 'type': 'ACTIVE_COMPARATOR', 'description': 'Conventional treatment: Topical treatment with compressive therapy, exercises of lower extremities, resting; once a week for 16 weeks.', 'interventionNames': ['Combination Product: Conventional treatment']}

Interventions:
- {'type': 'PROCEDURE', 'name': 'Low-level Light Therapy', 'description': 'Low-level Light Therapy 660nm (red laser), 1 to 3 Joules, irradiation time and number of points varied.', 'armGroupLabels': ['Intervention'], 'otherNames': ['Wavelength of 660 nm', 'red laser']}
- {'type': 'COMBINATION_PRODUCT', 'name': 'Conventional treatment', 'description': 'Topical treatment: essential fatty oil, hydrogel, papain gel, petrolatum gauze, calcium or silver alginate, zinc oxide and barrier cream; and high compression bandage SurePress', 'armGroupLabels': ['Controls', 'Intervention'], 'otherNames': ['Topical and compressive treatments']}

Primary Outcomes:
- {'measure': 'Decreased Wound Size and Scar formation', 'description': 'NOC Wound Healing: Second Intention - Greater length (in the cephalopheudial direction) versus greater width, in cm2 evaluated by the Likert scale, being 1 the worst score and 5 best score.\n\nNOC Wound Healing: Second Intention - Wound covered with epithelial tissue (new pink or bright tissue that develops from the edges or as "islands" on the surface of the lesion) evaluated by the Likert scale, being 1 the worst score and 5 best score.', 'timeFrame': '16 weeks'}

Please estimate the sample size based on the assumption: 
The study assumes a statistical power of 80%, a significance level of 5%, and accounts for a 20% dropout rate.
Sample size
        The WINPEPI program, version 11.43, was used to calculate the sample size. A sample of 34 subjects (nâ=â17 per group) would be able to detect a 1-point difference on a NOC indicator score between group means (laser intervention versus conventional control) as significant. The indicators are scored on 5-point Likert scales (range 1 to 5), in which the lowest score represents the worst possible state and the highest score represents the most desirable state after implementation of interventions. A change in one level, i.e., one point on the Likert scale, characterizes a positive effect of the intervention implemented throughout the treatment study, according to mixed linear models and generalized estimating equations. The standard deviation common to the groups [18], with a statistical power of 80% and significance level of 5% were defined for the study. To account for possible refusals and losses to follow-up, the sample was oversized by 20%. Thus, 40 subjects (nâ=â20 per group) will be recruited.