Here is the design of a clinical trial:

Official Title: Integrating Conservative Kidney Management Options and Advance Care Planning Into a Pre-Dialysis Educational Program

Included conditions:
- Advance Care Planning
- Chronic Kidney Diseases
- Conservative Kidney Management

Study Armgroups:
- {'label': 'Standard pre-dialysis education', 'type': 'NO_INTERVENTION', 'description': 'Standard pre-dialysis options education including hemodialysis, peritoneal dialysis, and kidney transplantation'}
- {'label': 'ESRD education + ACP', 'type': 'ACTIVE_COMPARATOR', 'description': 'Standard ESRD education + conservative kidney management and advance care planning education', 'interventionNames': ['Other: ESRD education + conservative kidney management and ACP education']}

Interventions:
- {'type': 'OTHER', 'name': 'ESRD education + conservative kidney management and ACP education', 'description': 'Targeted conservative kidney management and advance care planning education delivered in person by trained healthcare providers', 'armGroupLabels': ['ESRD education + ACP']}

Primary Outcomes:
- {'measure': 'Knowledge of Conservative Kidney Management and Advance Care Planning (Pre-intervention)', 'description': 'Knowledge of conservative kidney management and advance care planning pre-intervention (mean score) Total score ranges from 0 to 9, where 9 represents having the most knowledge about conservative kidney management and advance care planning', 'timeFrame': 'Pre-intervention and Day 1 post-intervention'}
- {'measure': 'Knowledge of Conservative Kidney Management and Advance Care Planning (Post-intervention)', 'description': 'Knowledge of conservative kidney management and advance care planning post-intervention (mean score) Total score ranges from 0 to 9, where 9 represents having the most knowledge about conservative kidney management and advance care planning', 'timeFrame': 'Immediate post-intervention'}

Please estimate the sample size based on the assumption: 
85% power
Power and sample size
          Based on the published data demonstrating poor knowledge of conservative kidney management among patients with advanced kidney disease,48 we anticipate that recruitment of 50 patients to each arm will provide 85% power to detect an effect size of 0.5 SD when comparing the change in knowledge of conservative kidney management and ACP between the two groups.49 50