Here is the design of a clinical trial:

Official Title: Treatment of COVID-19 Pneumonia With Glucocorticoids. A Randomized Controlled Trial

Included conditions:
- Covid-19 Pneumonia

Study Armgroups:
- {'label': 'Methylprednisolone Arm', 'type': 'EXPERIMENTAL', 'description': 'Standard of care plus Methylprednisolone', 'interventionNames': ['Drug: Methylprednisolone']}
- {'label': 'Placebo Arm', 'type': 'PLACEBO_COMPARATOR', 'description': 'Standard of care plus placebo', 'interventionNames': ['Other: Placebo']}

Interventions:
- {'type': 'DRUG', 'name': 'Methylprednisolone', 'description': '-A dose of 120 mg/day of methylprednisolone for 3 days, administered by intravenous infusión', 'armGroupLabels': ['Methylprednisolone Arm']}
- {'type': 'OTHER', 'name': 'Placebo', 'description': '-An infusion bag of 100 mL of 0.9% saline', 'armGroupLabels': ['Placebo Arm']}

Primary Outcomes:
- {'measure': 'Proportion of patients developing treatment failure', 'description': '• Death', 'timeFrame': 'At 14 days after randomization'}
- {'measure': 'Proportion of patients developing treatment failure', 'description': '• Need for admission in an intensive care unit (ICU)', 'timeFrame': 'At 14 days after randomization'}
- {'measure': 'Proportion of patients developing treatment failure', 'description': '• Need for mechanical ventilation', 'timeFrame': 'At 14 days after randomization'}
- {'measure': 'Proportion of patients developing treatment failure', 'description': '• Decrease in SpO2 \\<90% (in ambient air) or PaO2 \\<60 mmHg (in ambient air) or PaO2FiO2 \\<300 mmHg, associated with radiological impairment', 'timeFrame': 'At 14 days after randomization'}

Please estimate the sample size based on the assumption: 
Two-tailed type I error of 0.05, type II error of 0.2, and a loss to follow-up rate of 20%.
Numbers to be randomised (sample size)
          The percentage of patients with treatment failure (primary endpoint) is currently unknown. Assuming an absolute difference of 25% in the primary outcome between the two groups (35% in the control group and 10% in the intervention group), we estimate that 60 patients (30 per group) are required to detect this difference with a two-tailed type I error of 0.05 and a type II error of 0.2. Estimating a loss to follow-up of 20%, we should recruit a total sample size of 72 patients (36 per group).