Here is the design of a clinical trial:

Official Title: Individualized Precise Radiotherapy With the Guidance of Radiosensitivity: A Study on the Clinical Management Model of Locally Advanced Cervical Cancer

Included conditions:
- Cervical Cancer

Study Armgroups:
- {'label': 'PET/CT and Comet assay guided IMRT', 'type': 'ACTIVE_COMPARATOR', 'description': '18F-FDG PET/CT and Comet assay guide IMRT Based on FDG-PET/CT and comet analysis, higher doses of irradiation can be delivered to low sensitivity tumor region, so as to achieve individualized treatment.', 'interventionNames': ['Biological: 18F-FDG PET/CT and Comet assay guide IMRT']}
- {'label': 'PET/CT and Comet assay guided RapidArc', 'type': 'ACTIVE_COMPARATOR', 'description': '18F-FDG PET/CT and Comet assay guide RapidArc:\n\n1.A Rapid-Arc plan for cancer of the cervix uteri improved the sparing of organs at risk (OARs) with uncompromised target coverage. 2.Based on FDG-PET/CT and comet analysis, higher doses of irradiation can be delivered to low sensitivity tumor region, so as to achieve individualized treatment.', 'interventionNames': ['Biological: 18F-FDG PET/CT and Comet assay guide RapidArc']}
- {'label': 'RapidArc', 'type': 'ACTIVE_COMPARATOR', 'description': 'RapidArc:\n\nA maximum DR of 600 MU/min was set for comparing the 7f-IMRT treatment time. Two 360° coplanar arcs (one clockwise arc rotated from 181° to 179° and the other counter-clockwise arc rotated from 179° to 181°) sharing the same isocentre were used.', 'interventionNames': ['Biological: RapidArc']}
- {'label': '7f-IMRT', 'type': 'SHAM_COMPARATOR', 'description': 'seventy-five patients received IMRT. The 7f-IMRT gantry angles were 0°, 51°, 102°, 153°, 204°, 255° and 306°, with 20 intensity levels and a dose rate of 400 monitor units (MU)/min. Doses were delivered using the step-and-shoot method.Conventional fractionation was used in all patients for a total dose 45-50.4 Gy with 6 MV high-energy photons.', 'interventionNames': ['Biological: 7f-IMRT']}

Interventions:
- {'type': 'BIOLOGICAL', 'name': '18F-FDG PET/CT and Comet assay guide RapidArc', 'description': '1.A Rapid-Arc plan for cancer of the cervix uteri improved the sparing of organs at risk (OARs) with uncompromised target coverage. 2.Based on FDG-PET/CT and comet analysis, higher doses of irradiation can be delivered to low sensitivity tumor region, so as to achieve individualized treatment.', 'armGroupLabels': ['PET/CT and Comet assay guided RapidArc']}
- {'type': 'BIOLOGICAL', 'name': '18F-FDG PET/CT and Comet assay guide IMRT', 'description': 'Based on FDG-PET/CT and comet analysis, higher doses of irradiation can be delivered to low sensitivity tumor region, so as to achieve individualized treatment.', 'armGroupLabels': ['PET/CT and Comet assay guided IMRT']}
- {'type': 'BIOLOGICAL', 'name': 'RapidArc', 'description': 'RapidArc:\n\nA maximum DR of 600 MU/min was set for comparing the 7f-IMRT treatment time. Two 360° coplanar arcs (one clockwise arc rotated from 181° to 179° and the other counter-clockwise arc rotated from 179° to 181°) sharing the same isocentre were used.', 'armGroupLabels': ['RapidArc']}
- {'type': 'BIOLOGICAL', 'name': '7f-IMRT', 'description': 'seventy-five patients received IMRT. The 7f-IMRT gantry angles were 0°, 51°, 102°, 153°, 204°, 255° and 306°, with 20 intensity levels and a dose rate of 400 monitor units (MU)/min. Doses were delivered using the step-and-shoot method.Conventional fractionation was used in all patients for a total dose 45-50.4 Gy with 6 MV high-energy photons.', 'armGroupLabels': ['7f-IMRT']}

Primary Outcomes:
- {'measure': 'PFS', 'description': 'Progression-Free-Survival', 'timeFrame': '3 years'}

Please estimate the sample size based on the assumption: 
Not explicitly stated in the provided paragraph.
Study sample size and grouping method
        A total of 300 patients will be enrolled in the study. Due to the sample size, a block randomization procedure with randomly chosen block sizes is being used to assign participants to each group (1:1 ratio), resulting in one intervention and one control group. This method helps to maintain the balance of treatment assignment while reducing the potential for selection bias. Randomization is performed with random number generator of SPSS 20.0 software.