Here is the design of a clinical trial:

Official Title: Developing a Barbershop-Based Trial on Masculinity Barriers to Care and Colorectal Cancer Screening Uptake Among African-American Men Using a Mixed Methods Approach

Included conditions:
- Colorectal Cancer

Study Armgroups:
- {'label': 'Culture specific', 'type': 'EXPERIMENTAL', 'description': 'The culture-specific arm "may" entail FIT kits plus barbers as motivational interviewers.', 'interventionNames': ['Behavioral: Culture Specific']}
- {'label': 'Control', 'type': 'EXPERIMENTAL', 'description': 'Distribution of CRC screening brochures \\& FIT (Fecal Immunochemical Test) kits by barbers', 'interventionNames': ['Behavioral: Control']}

Interventions:
- {'type': 'BEHAVIORAL', 'name': 'Culture Specific', 'description': 'We anticipate the culture-specific arm developed minimally will include two core components: barbers as motivational interviewers, and (2) fecal immunochemical test (FIT) kits distributed by barbers. If we choose this route for the culture-specific arm, preliminary data from our barbers suggest I teach the barbers the MI technique using content that stems from Aim 1 findings. Additional components for this arm may be developed during the APEASE process.', 'armGroupLabels': ['Culture specific']}
- {'type': 'BEHAVIORAL', 'name': 'Control', 'description': 'the (control) arm will include an informational CRC screening brochure developed by the American Cancer Society plus a FIT kit distributed by the barbers.', 'armGroupLabels': ['Control']}

Primary Outcomes:
- {'measure': 'Scale development', 'description': 'Develop, validate, and test a culture-specific measure of masculinity barriers to medical care relative to psychosocial factors and CRC screening uptake among African-American men', 'timeFrame': 'Year 1-2'}

Please estimate the sample size based on the assumption: 
80% power at the 0.05 significance level, with an average screening rate of 35%. The relationship between the masculinity barriers to care index and confounders is assumed to be moderately strong (R2=0.25). If R2=0.2, power is 82%, and if R2=0.1, power is 87%.
Sample size and power considerations
          With a sample of 400 African-American men, we will have 80% power at the 0.05 level to detect a masculinity barriers to care effect on the odds of having had CRCS, assuming 35% of men with a masculinity barriers to care index equal to the mean have had CRCS compared with 25% of men with a masculinity barriers to care index 1 SD above the mean. We estimate that the average screening rate will be 35%, as the screening rate for AfricanÂ Americans is 53.1% in Utah and 52% in Minnesota and African-American men in both states tend to have lower CRCS rates than women.4 6 12 45 This assumes a moderately strong relationship between the masculinity barriers to care index and confounders (ie, R2=0.25 for the linear model that regresses the masculinity barriers to care index on the confounders). If the relationship between the confounders and the masculinity index is weaker, the power will be higher: 82% power with R2=0.2% and 87% power with R2=0.1. Power calculations were performed using PASS V.15.