Here is the design of a clinical trial:

Official Title: Preventing Infant Malnutrition With Early Supplementation, Aim 3

Included conditions:
- Underweight
- Wasting
- Stunting
- Breastfeeding
- Microbial Colonization

Study Armgroups:
- {'label': 'Early, Small-Volume Supplementation (ESVS)', 'type': 'EXPERIMENTAL', 'description': 'Breastfeeding with up to 59 mL formula daily until 30 days of age, followed by recommendation to breastfeed exclusively through 6 months of age', 'interventionNames': ['Other: ESVS']}
- {'label': 'Exclusive Breastfeeding', 'type': 'ACTIVE_COMPARATOR', 'description': 'Recommendation to breastfeed exclusively for 6 months without any other food or fluid except vitamins, minerals and medications', 'interventionNames': ['Other: Exclusive breastfeeding']}

Interventions:
- {'type': 'OTHER', 'name': 'ESVS', 'description': 'Breastfeeding with up to 59-mL formula daily for the first 30 days, followed by exclusive breastfeeding through 6 months of age', 'armGroupLabels': ['Early, Small-Volume Supplementation (ESVS)']}
- {'type': 'OTHER', 'name': 'Exclusive breastfeeding', 'description': 'Breastfeeding exclusively without any other food or fluid except vitamins, minerals and medications through 6 months of age', 'armGroupLabels': ['Exclusive Breastfeeding']}

Primary Outcomes:
- {'measure': 'Weight-for-age z-score (WAZ) at 30 days of age', 'description': 'WAZ calculated according to WHO Child Growth Standards', 'timeFrame': '30 days of age'}

Please estimate the sample size based on the assumption: 
The study assumes an 80% or greater power, a significance level that is not explicitly stated, and accounts for up to 20% loss to follow-up.
Sample size
        In each country, trained study staff will weigh up to 1,064 infants to identify and randomize 72 with birth weight â¤2500g and 90 who weigh <2600g on day 4. With respect to the primary aim, determining the impact of formula on WAZ at 30 days of infant age, the anticipated sample size of 324 dyads (144 LBW infants and 180 infants with low weight on day 4 under equal randomization) will provide 80% or greater power per weight stratum for intervention group comparison to detect a difference of 0.20 with respect to the outcome of WAZ at day 30 for the entire study cohort after accounting for up to 20% loss to follow-up. This sample size will also allow the estimation of the mean difference between WAZ at day 30 and WAZ at birth with 0.17 and 0.15 standard errors by intervention group, respectively, for the entire study cohort. Including both mothers and infants, the total sample size for the randomized trial is anticipated to be 324 mothers and 324 infants, or 648 individual participants in total.