Here is the design of a clinical trial:

Official Title: Community Health Worker And MHealth to ImProve Viral Suppression

Included conditions:
- HIV/AIDS

Study Armgroups:
- {'label': 'Intervention', 'type': 'EXPERIMENTAL', 'description': 'Wise App that delivers medication adherence reminders and community health worker sessions', 'interventionNames': ['Device: Wise App with medication adherence reminders', 'Behavioral: CHW Sessions']}
- {'label': 'Control', 'type': 'NO_INTERVENTION', 'description': 'Standard of care'}

Interventions:
- {'type': 'DEVICE', 'name': 'Wise App with medication adherence reminders', 'description': 'The Intervention group will receive the Wise App that delivers medication adherence reminders.', 'armGroupLabels': ['Intervention']}
- {'type': 'BEHAVIORAL', 'name': 'CHW Sessions', 'description': 'The Intervention group will complete sessions with a community health worker (CHW).', 'armGroupLabels': ['Intervention']}

Primary Outcomes:
- {'measure': 'Number of Virally Suppressed Participants', 'description': 'The number of virally suppressed participants. Viral suppression defined as viral load of \\<200 copies/mL.', 'timeFrame': '6 month follow up, 12 month follow up'}

Please estimate the sample size based on the assumption: 
Alpha level (α) of 0.05, 2-sided tests, 80% retention rate at each follow-up, correlation of 0.6 for outcome measures at different time points, intra-cluster correlation (ICC) of 0.2, and 75% baseline viral suppression rate.
Sample size calculation
        The statistical power was calculated based on the primary outcome of viral suppression (viral loadââ¤â200 copies/mL). 300 participants will be enrolled (nâ=â150 in each site) with a 1:1 random assignment to the intervention arm and the control arm (i.e., 75 in each arm per site). All power estimates are based on Î±â=â0.05 and 2-sided tests and the following assumptions: (1) an 80% retention rate at each follow-up assessment for each study arm; (2) a correlation of 0.6 of outcome measure for participants at different time points of assessment; (3) an intra-cluster correlation (ICC) of 0.2 of participants of same study sites; and (4) 75% baseline viral suppression rate (based on preliminary data of the BA2C study). For the total sample (nâ=â300), we calculated power of at least 80% in order to detect a difference of 12% or greater in viral suppression. The 12% difference in viral suppression is equivalent to a small effect size (Cohenâs D of 0.31).