Here is the design of a clinical trial:

Official Title: Effects of HABIT-ILE in Secondary Brain Damage Outcomes of Infants and Toddlers With Signs of Cerebral Palsy

Included conditions:
- Cerebral Palsy

Study Armgroups:
- {'label': 'HABIT-ILE', 'type': 'EXPERIMENTAL', 'description': 'Baby HABIT-ILE (Hand-Arm Bimanual Intensive Therapy Including Lower Extremities) intervention during two weeks', 'interventionNames': ['Behavioral: Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE)']}
- {'label': 'Regular care', 'type': 'ACTIVE_COMPARATOR', 'description': 'Usual customary care intervention during two weeks', 'interventionNames': ['Behavioral: Regular care']}

Interventions:
- {'type': 'BEHAVIORAL', 'name': 'Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE)', 'description': 'motor learning-based, intensive therapy for children with cerebral palsy', 'armGroupLabels': ['HABIT-ILE'], 'otherNames': ['Baby HABIT-ILE']}
- {'type': 'BEHAVIORAL', 'name': 'Regular care', 'description': 'customary or usual care given to any infant/toddler with cerebral palsy', 'armGroupLabels': ['Regular care'], 'otherNames': ['Usual care']}

Primary Outcomes:
- {'measure': 'Changes on the Mini-Assisting Hand Assessment (Mini-AHA)', 'description': 'Measures how well infants (8-18 months) with signs of unilateral or hemiplegic cerebral palsy use their more affected hand, when using both hands together to play (scored in percentage).', 'timeFrame': 'baseline, 3 weeks, 13 weeks and 26 weeks after baseline'}

Please estimate the sample size based on the assumption: 
Significance level (α) = 0.05, Power (1−β) = 0.9, and consideration of potential dropouts and data loss in MRI.
Sample size calculation
        The sample size calculation was performed based on the Assisting Hand Assessment (AHA36) score of a HABIT-ILE pilot study performed in 10 infants with unilateral CP.34 In this pilot study, toddlers with unilateral CP (1â4 years old) encountered an intensive intervention of 50 hours over 2 weeks, as in the present study. A mean improvement of 8.2 AHA units (SD=5.9âAHA units) after the intensive therapy was reported. Thus, our hypothesis is an incremental improvement of 1 SD between the immediate group and the delayed group at second and third assessments (between group difference=7.2, SD=5.9). With Î±=0.05âand a 1âÎ²=0.9, a sample size of 15 participants per group is required. Considering potential dropouts and data loss in MRI, 24 participants will be included in each group (48 in total).