Here is the design of a clinical trial:

Official Title: A Randomised Controlled Trial of Multimodal Physiotherapy for Patients With Acute / Sub-acute Cervical Radiculopathy

Included conditions:
- Cervical Radiculopathy

Study Armgroups:
- {'label': 'Multimodal physiotherapy group', 'type': 'EXPERIMENTAL', 'description': '4 week multimodal physiotherapy treatment programme provided by an experienced musculoskeletal physiotherapist', 'interventionNames': ['Other: Multimodal physiotherapy']}
- {'label': 'Advice to stay active group', 'type': 'NO_INTERVENTION', 'description': 'Advice to stay active and continue use of prescribed medication as appropriate, via weekly phone calls from a physiotherapist over a 4 week period.'}

Interventions:
- {'type': 'OTHER', 'name': 'Multimodal physiotherapy', 'description': 'Manual therapy, exercise and neural unloading tape provided twice weekly over 4 weeks by an experienced musculoskeletal physiotherapist', 'armGroupLabels': ['Multimodal physiotherapy group']}

Primary Outcomes:
- {'measure': 'Change from baseline in neck and arm pain (Numerical Pain Rating Scale)', 'description': 'Neck and arm pain levels measured with the Numerical Pain Rating Scale for current, best and worst pain levels over last 24 hours (Jensen et al 1994)', 'timeFrame': '4 weeks'}
- {'measure': 'Change from baseline in Neck Disability Index', 'description': 'Disability resulting from the cervical radiculopathy measured with the Neck Disability Index (Vernon and Mior 1991)', 'timeFrame': '4 weeks'}

Please estimate the sample size based on the assumption: 
Two-sided 5% significance level, 80% power, and an additional 10% to account for anticipated dropout.
Sample size estimation
        The NDI and the NPRS are the independent primary outcome measures and sample size estimates were carried out for both outcome measures. An MCID for the NDI of 7 has been determined for cervical radiculopathy [48]. Using a reported NDI SD of 9.2 [48] for this patient group, with a two-sided 5% significance level and a power of 80%, a sample size of 29 participants per group is necessary. An MCID for the NPRS of 2 has been determined for mechanical neck pain, including cervical radiculopathy [43] and a SD of 1.85 [48]. Using these figures, with a two-sided 5% significance level and a power of 80%, a sample size of 15 per group was calculated. An online sample size calculator [49] for comparing means of 2 independent groups, that utilises reference tables [50] was used. The larger sample size per group calculated using the NDI was chosen and an additional 10% was added to account for anticipated dropout. In total, a sample size of 64 participants will be recruited.