Here is the design of a clinical trial:

Official Title: Development and Evaluation of Culturally Adapted CBT to Improve Community Mental Health Services for Canadians of South Asian Origin

Included conditions:
- Depression
- Anxiety

Study Armgroups:
- {'label': 'Culturally adapted CBT', 'type': 'EXPERIMENTAL', 'description': 'Ca_CBT will be delivered to the experimental group using the newly developed manual . The intervention will be delivered over 8-12 sessions. The Control group will receive standard CBT', 'interventionNames': ['Behavioral: Culturally adapted CBT']}
- {'label': 'Standard CBT', 'type': 'ACTIVE_COMPARATOR', 'description': 'Participants in this group will receive standard CBT', 'interventionNames': ['Behavioral: Culturally adapted CBT']}

Interventions:
- {'type': 'BEHAVIORAL', 'name': 'Culturally adapted CBT', 'description': 'Culturally adapted CBT for South Asian Canadians', 'armGroupLabels': ['Culturally adapted CBT', 'Standard CBT'], 'otherNames': ['CaCBT']}

Primary Outcomes:
- {'measure': 'Hospital Anxiety and Depression Scale', 'description': 'HADS is a 14-item, self-assessment scale designed to measure anxiety and depression. The maximum score is 21 for depression and 21 for anxiety. A score of 8 - 10 suggests the presence of the borderline cases, while a score of 11 - 21 indicates abnormal cases.', 'timeFrame': '36 weeks'}

Please estimate the sample size based on the assumption: 
5% significance level, 90% power, and up to 30% attrition rate.
Sample size calculation
            The sample size was calculated using a comparison between group change in the HADS Depression subscale scores. With a 5% significance level and 90% power, we determined that 48 subjects per group will be required for the trial, in order to detect a standardized effect size Cohenâs d = 0.68, which is equivalent to a difference in HADS score at the end of the trial of around 2.4 points, assuming a standard deviation of 3.5 found in previous studies from our lab that used the same outcome. To account for up to 30% attrition, we plan to recruit a total of 140 participants into the study.