Here is the design of a clinical trial:

Official Title: Effect of Different Form of Upper Limb Muscles Training on Dyspnea in COPD

Included conditions:
- COPD

Study Armgroups:
- {'label': 'Strength', 'type': 'EXPERIMENTAL', 'description': 'Patients will follow the pulmonary rehabilitation program associated with upper limbs strength training for a duration of 4 weeks', 'interventionNames': ['Other: Strength training']}
- {'label': 'Endurance', 'type': 'ACTIVE_COMPARATOR', 'description': 'Patients will follow the pulmonary rehabilitation program associated with upper limbs endurance training for a duration of 4 weeks', 'interventionNames': ['Other: Endurance training']}

Interventions:
- {'type': 'OTHER', 'name': 'Strength training', 'description': 'Upper limbs Strength training; done with dumbbells whose weight corresponds to 60-80% of the maximal voluntary force in abduction measured initially, during 4 weeks', 'armGroupLabels': ['Strength']}
- {'type': 'OTHER', 'name': 'Endurance training', 'description': 'Upper limbs Endurance training of the ; done with dumbbells whose weight corresponds to 30% of the maximum voluntary force in abduction measured initially, during 4 weeks', 'armGroupLabels': ['Endurance']}

Primary Outcomes:
- {'measure': 'Compare the effect of upper limbs strength training versus the effect of upper limb endurance training on dyspnea in patients with COPD during a pulmonary rehabilitation program.', 'description': 'Measurement of dyspnea using the London Chest Daily Activity Living (LCADL) questionnaire.\n\nThis 15-item, self-administered questionnaire allows an evaluation of dyspnea in patients with COPD during daily activities divided into four components: self-care, domestic, physical, and leisure. Patients could score from 0: "I would not do anyway" to 5: "I need someone else to do this". LCADL score is calculated by aggregating the points assigned to each question, with a higher score representing maximal disability.', 'timeFrame': 'Change from inclusion at 4 week'}

Please estimate the sample size based on the assumption: 
α-error of 5% and β-error of 10%.
2.7
        Sample size calculation
        A previous study[29] (EMI2) reported a standard deviation of 10 points for the LCADL score. A 4-point improvement for LCADL during a pulmonary rehabilitation program would be clinically significant.[24,25]
        With these assumptions, for an Î±-error of 5% and Î²-error of 10%, the expected sample size would therefore be 133 patients per group. In order to anticipate loss to follow-up or withdrawals of consent, 140 patients per group will be included, or 280 in total.