Here is the design of a clinical trial:

Official Title: Effect of the Intensive Intervention "Hand-Arm Bimanual Intensive Therapy Including Lower Extremities" (HABIT-ILE) in Chronic (> 6 Months) Adults With Acquired Brain Damage (Stroke)

Included conditions:
- Stroke

Study Armgroups:
- {'label': 'HABIT-ILE', 'type': 'EXPERIMENTAL', 'description': 'HABIT-ILE (Hand-Arm Bimanual Intensive Therapy Including Lower Extremities) intervention during two weeks adapted for adults stroke survivors', 'interventionNames': ['Behavioral: Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE)']}
- {'label': 'Regular care', 'type': 'ACTIVE_COMPARATOR', 'description': 'Usual customary treatment for adults stroke survivors during two weeks', 'interventionNames': ['Behavioral: Regular care']}

Interventions:
- {'type': 'BEHAVIORAL', 'name': 'Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE)', 'description': 'motor learning-based, intensive therapy originally developed for hemiplegic children.', 'armGroupLabels': ['HABIT-ILE'], 'otherNames': ['HABIT-ILE Stroke']}
- {'type': 'BEHAVIORAL', 'name': 'Regular care', 'description': 'customary or usual treatment given to any adult stroke survivor', 'armGroupLabels': ['Regular care'], 'otherNames': ['Usual care']}

Primary Outcomes:
- {'measure': 'Changes on the Adult Assisting Hand Assessment Stroke (Ad-AHA Stroke)', 'description': 'This assessment is an observation-based instrument assessing the effectiveness of the spontaneous use of the affected hand when performing bimanual activities in adults post stroke scored in a logit based 0-100 AHA-unit scale (higher score indicate higher ability)', 'timeFrame': 'baseline, 3 weeks and 13 weeks after baseline'}

Please estimate the sample size based on the assumption: 
Significance level (α) = 0.05, Power (1-β) = 0.9, and considerations for potential dropouts and data loss.
Sample size
        Since this is the first time HABIT-ILE will be proposed to adults with stroke, the sample size was calculated regarding motor changes observed in a previous study of HABIT-ILE in school-aged children with congenital brain lesions.21 Based on the results of the Assisting Hand Assessment changes, a similar effect size is expected here. Thus, we hypothesise an incremental improvement of 1 SD between the intervention group and the control group (between-group difference=6, SD=5). With an Î±=0.05âand a 1âÎ²=0.9, a sample size of 16 participants should be included in each group (32 total). Considering potential dropouts and data loss in assessments, 24 participants per group (48 in total) will be included.