text:
Stiles T. Howdy everyone. I hope everyone is planning to attend tonight. Due to unforeseen circumstances, I will not be there. I wish I could be! I believe Jason will be taking care of everyone tonight. He's a great guy. I will be back and ready to teach a belay class for anyone who needs it next week. Hope everyone had a great New Year and I'm looking forward to seeing y'all next week! 0 · January 2, 2014 Brian R. Hello, I joined OCS today and plan to join in on the climbing next week, looking forward to it. I'm a definite beginner. 0 · January 2, 2014 Amanda Z. Sorry can't make it tonight, too tired from travelling but will be back next week! 0 · January 2, 2014 A former member I dont know how to climb yet! 0 · January 1, 2014 Adria I am really interested in doing this but I have only rock-climbed once and don't really know how it would work with finding someone to Belay etc. Can you please tell me more? 0 · December 16, 2013 6 went
401 Boaters

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text:
Leila Beltaïfa Zouari - Semantic Scholar
Leila Beltaïfa Zouari
D Pullella11
R Togneri11
Robert B. Dunn7
4Rania Chakroun
4Mondher Frikha
2Ahmed Ben Hamida
1Anna Přibilová
1Jiří Přibil
An Improved Approach for Text-Independent Speaker Recognition
Rania Chakroun, Leila Beltaïfa Zouari, Mondher Frikha
This paper presents new Speaker Identification and Speaker Verification systems based on the use of new feature vectors extracted from the speech signal. The proposed structure combine between the… (More)
A novel approach based on Support Vector Machines for automatic speaker identification
Rania Chakroun, Leila Beltaïfa Zouari, Mondher Frikha, Ahmed Ben Hamida
Over the past decade, the field of automatic speaker recognition has been the subject of extensive research looking for an efficient determination of a person's identity. Despite the essential role… (More)
Efficient Parameterization for Automatic Speaker Recognition Using Support Vector Machines
Rania Chakroun, Mondher Frikha, Leila Beltaïfa Zouari
Recent advances in the field of speaker recognition have proved to highly outperform algorithms. However this performance degrades when limited data are presented. This paper presents examples on how… (More)
A hybrid system based on GMM-SVM for speaker identification
Gaussian mixture models (GMM) have become the standard method used for speaker recognition systems. A recent discovery is that combining GMM approach with another classifier is an effective method… (More)
Improving text-independent speaker recognition with GMM
The Gaussian mixture models (GMM) represent an efficient model that was broadly used in most of speaker recognition applications. This study introduces a novel method for speaker verification task.… (More)

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text: We found 0 results for "" Check your spelling or use different keywords and try again. If you are searching for help information, please select "Help" from the list of departments and try the search again. Some products available in stores may not be listed online — contact your local store to see if they carry what you are looking for. Walmart Sterling 45415 Dulles Crossing Plz Sterling, VA 20166 Ph. (571) 434-9434 Find another store Showing 0 of 0 results Compute- app-11031075-7-52924350, DC- prod-dfw4, ENV- prod-a, Ver- 40.0.0, SHA- 99e97d1a1f9fc08d509d0fdf443b4323885a23af, Log- 8f2f0cd2-66-154ecbb0e15000 Site Information Be the first to save! Email Address Sign up Privacy policy Stay connected Mobile apps Help Feedback MoneyCenter Privacy & Security CA Privacy Rights Terms of Use Financial Services Walmart MoneyCenter Walmart Credit Card Apply Now Manage Card Account Product Care Plans Walmart Pay Get to Know Us About Walmart.com Corporate Suppliers Marketplace Careers @Walmartlabs Walmart.com Terms of Use About Our Ads Affiliate Program CA Privacy Rights Privacy & Security Customer Service Returns Policy Product Recalls Int'l Customers Tax Exempt Program Contact Us Feedback In the Spotlight Expand Baby Cribs Strollers Diapers Baby Feeding Car Seats Expand Electronics Cut the Cable Computers TVs iPad & Tablets Expand Fitness Exercise Machines Vitamins Ellipticals Treadmills Fitbit Expand Spring Cleaning Storage Containers Garage Storage Storage Sheds Expand International Sites Argentina Brazil Canada Chile China Japan Mexico United Kingdom © Walmart Stores, Inc. To ensure we’re able to help you as best we can, please include your reference number: Ref:

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DC jewelry making club (Washington, DC) | Meetup
“This is a group for anyone interested in learning to make real jewelry and to explore their creative side and to give aspiring metalsmiths access to a fully equipped and professional studio space. If you have craved an introduction to jewelry making, this group is for you. All skills levels are welcome.
You may join this group FREE. The Instructor/Organizers donate their time to this group. All fees are for precious materials used only. From beginners to professional Goldsmiths, this is a community for all interested in promoting and learning metalsmithing.
http://photos2.meetupstatic.com/photos/event/1/0/4/600_448020260.jpeg
I started this group because I feel there are many locals looking to get into jewelry making but who are hesitant due to cost etc . If you would like to explore the incredible world of Jewelry making, If you would like to attend FREE meetups, Gem shows, open houses and workshops at a professional Metalsmithing studio with access to all the latest equipment, from hydraulic press to the newest laser welder, join us.
Jewelry MakingCraftsHandmade CraftsWire jewelryJewelry and accessory crafting funMake it & Take it Jewelry WorkshopsBeadingJewelry LoversJewelry Making TechniquesMetalsmithingBasics of metalsmithing for jewelryJewelry AddictsHandmade


text:
visual studio - Could not load file or assembly in VS2017 with IIS express - Stack Overflow
Could not load file or assembly in VS2017 with IIS express
We have a ASP.NET project in the company that runs for 5/6 developers. All Visual Studio 2017 and debug on IIS Express, no crazy setting or anything to make it run.
1 colleague cannot get it to work, he always gets the following exception:
We had this problem a few months back, then out of frustration the PC was re-installed and the problem was gone. He didn't develop for a few weeks and today the problem appeared again.
I searched long and far but it's such a generic error I can't really figure this one out.
When I run the fusion log viewer I see the following result:
https://pastebin.com/aCVZn3EB
Running under executable  C:\Program Files\IIS Express\iisexpress.exe
LOG: DisplayName = System.ServiceModel.Activities, Version=4.0.0.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35
LOG: Appbase = file:///C:/Users/User/Projects/project/project.UserSite/
LOG: Initial PrivatePath = C:\Users\User\Projects\project\project.UserSite\bin
LOG: Dynamic Base = C:\Users\User\AppData\Local\Temp\Temporary ASP.NET Files\vs\e0254dae
LOG: Cache Base = C:\Users\User\AppData\Local\Temp\Temporary ASP.NET Files\vs\e0254dae
LOG: AppName = 38c6ff11
LOG: Using application configuration file: C:\Users\User\Projects\project\project.UserSite\web.config
LOG: Using host configuration file: C:\Users\User\Documents\IISExpress\config\aspnet.config
LOG: Binding succeeds. Returns assembly from C:\WINDOWS\Microsoft.Net\assembly\GAC_MSIL\System.ServiceModel.Activities\v4.0_4.0.0.0__31bf3856ad364e35\System.ServiceModel.Activities.dll.
*** Assembly Binder Log Entry  (7/18/2017 @ 8:55:15 AM) ***
edited Jul 18 '17 at 15:09
asked Jul 7 '17 at 22:47
Roger FarRoger Far
1,14333 gold badges3030 silver badges6262 bronze badges
Just for fun, can you go into the solution > Reference > System.ServiceModel.Activities > Properties and verify that the property "specific Version" is set to false. – Travis Acton Jul 10 '17 at 15:25
@TravisActon yes it's set to false. – Roger Far Jul 10 '17 at 22:24
Is there anything further down the stack trace? Perhaps something in the event log? – Henrik Clausen Jul 13 '17 at 18:07
Enable fusion log to locate where this problematic assembly is (its full path), and then use a tool such as ILSpy to analyze the assembly and compare with another machine. – Lex Li Jul 14 '17 at 18:04
stackoverflow.com/questions/255669/… and after analyze log – Mihail Kuznesov Jul 17 '17 at 5:18
Are you trying to load a .NET 4 assembly with an EXE that asked for a diferrent CLR version? That requires an app.exe.config file that forces CLR 4 to be used.
Also please check the he has the same version of .NET installed.
Mihail StancescuMihail Stancescu
3,67011 gold badge1111 silver badges1919 bronze badges
@YesMan85: What exactly was the problem and solution? – one_mile_run Jul 19 '17 at 6:23
@one_mile_run see my own answer. – Roger Far Jul 19 '17 at 14:07
1- Close Visual Studio
2- Delete all files from "C:\WINDOWS\Microsoft.NET\Framework......\Temporary ASP.NET"
3- Open VS
4- Rebuild then run
answered Jul 15 '17 at 20:55
Yazan.AtiYazan.Ati
First thing I tried, unfortunately didn't help. – Roger Far Jul 16 '17 at 21:15
I have the same issue, its random. Just install missing package via Nuget for that project. Open Package Manager Console and type:
PM> Install-Package System.ServiceModel.Activities
and go on installing packages till there is no more error: then stop.
answered Jul 17 '17 at 10:01
one_mile_runone_mile_run
1,63533 gold badges1818 silver badges2424 bronze badges
It does work fine on the rest of our machines so this would be a last resort, it would increase the build time and artifact size quite a bit. – Roger Far Jul 17 '17 at 15:07
Turns out with the help of Fusion Log I found 1 file that was 0kb in size: C:\WINDOWS\Microsoft.Net\assembly\GAC_MSIL\System.ServiceModel.Activities\v4.0_4.0.0.0__31bf3856ad364e35\System.ServiceModel.Activities.dll
I restored the file from C:\Windows\Microsoft.NET\Framework64\v4.0.30319\System.ServiceModel.Activities.dll and it worked again!
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text:
Big Ten Conference football spring notebook: East Division - Big Ten Blog- ESPN
Big Ten spring notebook: East Division754dJosh Moyer and Austin WardLessons learned from spring practice: Penn State Nittany Lions30mJosh MoyerWhat's the end game for satellite camps? Look to Jim Delany for insight2hMitch ShermanWhich non-traditional programs are making noise in 2017?2hTom VanHaarenLessons learned from spring football: Purdue Boilermakers21hJosh MoyerBuckeyes to get plenty of prime-time appearances on ESPN networks15hMitch ShermanLessons learned from spring football: Rutgers Scarlet Knights23hMitch ShermanLessons learned from spring football: Wisconsin1dJesse TempleB1G roundtable: Which Day 3 draft pick will surprise in the NFL?1dESPN.com staffScout's take: Joshua Kaindoh to Maryland3dCraig HaubertBilly Devaney lends an NFL scouting eye to evaluations at Nebraska4dMitch ShermanB1G roundtable: Which drafted player will have best NFL career?4dESPN.com staffSpring breakout player: Wisconsin Badgers4dJesse TempleTakeaways from the stunning and silly satellite camp saga4dAdam RittenbergSpring breakout player: Rutgers Scarlet Knights4dJosh MoyerDesmond's destiny: Iowa star King feels no regret as senior year awaits4dMitch ShermanBig Ten spring notebook: East DivisionEmailcommentApr 10, 2014Josh MoyerCloseJosh MoyerESPN Staff WriterCovers Penn State and Big Ten.Joined ESPN in 2012.Graduate of Penn State University and Columbia University.Follow on TwitterAustin WardCloseAustin WardESPN Staff WriterCovers the Big Ten.Joined ESPN in 2012.Attended the University of Wyoming.Follow on TwitterEmailprintcommentHead coaches from the Big Ten East Division, along with a player from each team, addressed the media this afternoon on teleconferences. The West Division players and coaches spoke Wednesday.Here's a closer look at the East:INDIANADefense has been a lingering Indiana concern for years, but coach Kevin Wilson believes he's starting to see a change, thanks to new defensive coordinator Brian Knorr. The scheme hasn't changed radically, but the Hoosiers return 10 starters there -- and Wilson's seen a promising spring so far with an added focus on competition and communication: "They've for sure held their own on a daily basis -- and, in some ways, probably even better -- against the offense."Wilson believes teams need to invest scholarships into the kicking game, but he thinks it's also too risky to offer recruits straight out of high school. If you look at the NCAA's top 25 kickers, Wilson estimated at least 15 started out as walk-ons. So he's hoping to find some walk-ons who are willing to work for a scholarship, rather than be granted one right away.At 5-foot-7, Shane Wynn is the Hoosiers' leading returning receiver, and he's transitioning to playing the outside. It's been a little different for Wynn, who said he's had to watch more film as a result. He's reading the corners now, instead of the safeties, as just one example.MARYLANDMaryland coach Randy Edsall is confident in his offense and believes the Terrapins have enough options so that opponents can't focus on just one person. If defenses lock on to wideout Stefon Diggs, then quarterback C.J. Brown can take off running or receiver Deon Long can pick up some slack. "The No. 1 thing I do like," Edsall said, "is we can spread the field."Maryland's staff has already started looking at film of Big Ten teams, so they know what to expect when the conference season begins. Edsall said he wants to at least get a feel for their personnel and what kind of schemes he'll face. He's also confident the Terps will be ready: "We fully expect to be able to compete when we get into the Big Ten this year."Brown said one of the main reasons he committed to Maryland was the coach who recruited him at the time, former Terps assistant and current Penn State coach James Franklin. He's looking forward to squaring off against Franklin this season, and Edsall said there's no question he would like to develop a rivalry with the Nittany Lions.MICHIGANThe quarterback derby will continue, and Brady Hoke included all three of his options in the discussion heading into the offseason. The Wolverines coach did acknowledge, though, that Devin Gardner “probably would be” the starter if there was a game on the schedule this weekend. There isn’t, so Shane Morris and Wilton Speight will continue to be in the conversation.The first opponent on the schedule will always stir emotions for Michigan fans, but Hoke didn’t attach any revenge or sentimentality to his reasons for wanting to take on Appalachian State in the opener this fall. “We needed a game,” Hoke said. “I thought it would be a good game.” Defensive end Frank Clark was certainly aware of the history between the programs, even though he was still years away from joining Michigan and getting a shot at making up for the upset loss in 2007 -- which he called “shocking” and “shows how hard those guys play.”MICHIGAN STATEMichigan State is coming off a Rose Bowl victory, but coach Mark Dantonio and quarterback Connor Cook would prefer not to think about that any longer. Dantonio said they've talked a lot these last four months about not growing complacent, and Cook only echoed his coach. "A lot of people keep bringing up the Rose Bowl," Cook said. "But we're past that. We're focusing on the now."The offensive line has made some big strides since January, at least according to Cook. He felt like he had no time in the pocket last spring and said the pass rush was getting to him every time. This spring? He doesn't feel rushed in the pocket, and he thinks that's pretty indicative of how far this line has come.Jeremy Langford earned a lot of praise from Cook, who said the running back has become a much bigger part of the passing attack. "He's improved a lot with catching the ball," Cook said, complimenting Langford's versatility. "He's done so many different things for us."OHIO STATEThere is still work to be done in addressing the most glaring weakness on the team last season, but Urban Meyer called Ohio State’s pass defense “drastically improved” and will be watching closely for more signs of progress in Saturday’s spring game. The Buckeyes will play a traditional game, but the emphasis will be on throwing the football and assessing the skill players on both offense and defense -- giving Meyer a chance to evaluate backup quarterback Cardale Jones in a live setting in addition to checking out the secondary.Arguably the strongest part of last season's team is undergoing a transition without four senior starters, and the offensive line is somewhat of a concern for Meyer heading into the offseason. With guard Pat Elflein the only other player to have earned a first-team slot to play alongside junior Taylor Decker at this point, that competition is likely to spill over into preseason camp in August. Both tackle Darryl Baldwin and guard Antonio Underwood were praised for their work by defensive tackle Michael Bennett, and Billy Price and Jacoby Boren are dueling at center.PENN STATEFranklin said he knew exactly what he was getting into at Penn State, in terms of the current depth and sanctions. He and former coach Bill O'Brien worked together at Maryland, and he said the two had a lot of honest conversations about the current state of the Nittany Lions. The two have continued to talk since.Derek Dowrey and Brian Gaia are both making transitions from defensive tackle to offensive guard, and Franklin said he has been pleased with their performances so far: "They're doing a good job for us -- and they have to. We're thin at that position."Franklin said he feels especially comfortable with the talent at running back and defensive line. Middle linebacker Mike Hull was more specific about naming the players who impressed him, pointing to backup linebacker Gary Wooten and cornerback Da'Quan Davis. Hull said Wooten is always around the football and that Davis, who missed part of the spring with a hamstring injury, has come up with several interceptions.RUTGERSAnother open competition at the most critical position on the field -- quarterback -- is still playing out at Rutgers, and coach Kyle Flood isn’t ready to declare a winner in what would seem to be a wide-open battle. Flood indicated that Gary Nova, Mike Bimonte and Chris Laviano are all “really vying for that first-team job.”The change in conference affiliation has been welcomed with open arms by the Scarlet Knights, who can “feel the energy” as theypractice for their first season in the Big Ten. Defensive tackle Darius Hamilton said the team was already buzzing with excitement about the opportunity, and Flood called joining the league a “positive in every way.” The move also presents the opportunity for a rivalry to develop with new divisional neighbor Penn State, with both Flood and Hamilton citing the proximity between the schools as a bonus.

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text:
Rooms good - Review of Hilton Austin, Austin, TX - TripAdvisor
Rooms good - Hilton Austin
Hotels near The Stage on Sixth
Back to Hilton Austin
English first French first German first Italian first Japanese first Portuguese first Spanish first Any 133-137 of 641 reviews
This hotel is centrally located. The front desk manager was rude. The rest of staff was very helpful. Rates change based on occupancy and can vary several hundred dollars. The rooms are very nice and the hotel is clean and has a very good bar. The executive lounge has a good evening reception and a nice breakfast offering.
See 4 more reviews by BillyBiii for Austin Ask BillyBiii about Hilton Austin
Great place to stay in Austin. Stayed on an Executive Level floor with the Executive Lounge. Great breakfast and evening appetizer service. Very clean and nicely updated hotel. No problems whatsoever. The location is amazing. One block from the bars of Sixth Street. Many great restaurants in walking distance and lots of sights nearby. Easy access to the Interstate for day trips to local vineyards. The staff at the hotel was very friendly and helpful. They have great maps to show you the downtown area with local restaurants and were great with recommendations. Would definitely recommend to anyone traveling to Austin. The gym is the best I've seen at a hotel with a cardio room and separate weight room. The pool was great with plenty of towels, shaded areas, a hot tub and lots of chairs. We didn't experience any problems or have any complaints whatsoever.
Room Tip: Executive floor was great with wonderful view of the Capital, 6th Street and the Longhorns stadium.
See 6 more reviews by Volawyer for Austin Ask Volawyer about Hilton Austin
“Overall First Class”
I stayed here 3 nights and would recommend it if you can get a reasonable deal (I used a discounter site to book). Location is downtown 2 blocks from the 6th St. scene and walking distance to the Driskill historic hotel and Congress Ave, where there are more restaurants and the bridge where the bats are.Room was well maintained, well appointed and pleasant, and I appreciated that they did not skimp on the toiletries. Bed was very comfortable and the climate control worked well. Front desk staff was efficient and pleasant. There is a cafe with Starbucks coffee and snacks, pastries by the lobby. But the room does have a coffee/tea maker in it. Overall a high-end experience that I would expect for a Hilton.
See 5 more reviews by RFJ for Austin Ask RFJ about Hilton Austin
“A great location for wandering downtown Austin”
My friends and I stayed here for my birthday weekend. It is very close to all the bars, music and restaurants and you can walk to everything. The hotel is also right next to a rail station if you need to go further or don't want to walk.If you have a car, parking is a little annoying. The spots are small and tight and it was difficult to find a spot when we did have to use the car. The hotel staff was great and very helpful. We all had adjoining rooms and all of our rooms were updated and clean. Room service and housekeeping were fast and the rooms were always clean and restocked when we came back. The showers were hot with great water pressure (really important for me) and all the bathrooms were very clean.I've stayed at quite a few Austin hotels over the years that are also close to the downtown action but this is the first hotel that I've been completely satisfied with (I can deal with parking in comparison to the issues I've had at the other hotels in the area). One tip for smokers - there is a cool large corner balcony on I think the 4th floor that my smoker friends found. It holds a lot of people and you can watch all of the evening action below from there too.
Room Tip: Ask for a corner room (they're larger and the same price as the others).
Ask Theodora8 about Hilton Austin
“Good location and no line front desk”
I stayed the downtown Austin Hilton for 4 nights for a business trip.It was a great location; coffee shops, restaurants, and plenty of bars. I was able to walk around the downtown at nights checking out the nightlife in Austin.A light rail stop is in front of hotel if you want to hop on to go outside of downtown. Front desk staff is fast, I didn't have to wait to check in or out. I rarely see a line at the front desk even though the hotel was completely full due to the conference I was attending. It has a clean gym, but the swimming pool is rather small.
Room Tip: Lower level is better than high level if you don't want to stop every floor between lobby and yo...
Ask ch2001Sea about Hilton Austin
133-137 of 641 reviews Hilton Austin
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Free Guide to Austin Get your guide to the top local hotels, restaurants and things to do Hilton Austin Photos (145 traveler photos) More Reviews of this Hotel "Executive floor worth the service"
4.5 out of 5, 643 reviews Last reviewed May 19, 2013
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text:
c++ - Is it necessary to pass iterator by const reference - Stack Overflow
Is it necessary to pass iterator by const reference
unordered_map<string, int> table;
void updateA(const unordered_map<string, int>::iterator& iter)
iter->second = 100;
void updateB(unordered_map<string, int>::iterator iter)
Question> Which function is better(i.e. updateA or updateB)? If you have a better one, please propose.
c++ share|improve this question asked Jun 27 '13 at 2:53
If you are not going to change the value of the iterator it is definitely better to use the const one
I believe most, if not all, of the standard functions take iterators by value.
Jun 27 '13 at 2:58
@chris yup looks like your right I'm guessing that is because iterators are never very large
@aaronman, I'm not too familiar with them on a low level, but I would imagine the only thing they are expected to be in any reasonable implementation is really just a pointer or an index.
@chris I would guess that a smart compiler could probably optimize iters out of the code, in the end they are really just there to write better more readable code
1) First, to answer the question in the title, is it necessary to pass iterators by (const) reference: No. An iterator acts as a proxy for the data item in the container, regardless of whether or not the iterator itself is a copy of or a reference to another iterator. Also in the case when the iterator gets invalidated by some operation performed on the container, whether you maintain it by copy or reference will not make a difference.
2) Second, which of the two options is better.
I'd pass the iterator by copy (i.e. your second option).
The rule of thumb is: Pass by reference if you either want to modify the original variable passed to the function, or if the object you pass is large and copying it involves a major effort.
Neither is the case here: Iterators are small, lightweight objects, and given that you suggested a const-reference, it is also clear that you don't want to make a modification to it that you want reflected in the variable passed to the function.
3) As a third option, I'd like you to consider adding const to your second option:
void updateC(const unordered_map<string,int>::iterator iter)
This ensures you won't accidentally re-assign iter inside the function, but still allows you to modify the original container item referred to by iter. It also may give the compiler the opportunity for certain optimizations (although in a simple situation like the one in your question, these optimizations might be applied anway).
answered Jun 27 '13 at 3:36
C++ conversion const pass-by-reference


text:
bahawalshertrading (59691 )
More than 10 available / 7,487 sold / See Feedback
Last updated on 23 Sep, 2019 15:22:58 BST View all revisions
There are 26,520 items available. Please enter a number less than or equal to 26,520.
as described,beautiful!! arrived speedily! great seller
No fuss experience, recommended seller..
Excellent item great quality super fast delivery thank you
PVC Venetian Blind Blinds

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Amazon.com : Shed-x Dermaplex Shed Control Nutritional Supplement for Cats - 8 Fl. Oz. : Pet Supplies
Only 7 left in stock - order soon. Sold by StarBunch
Sold by: EpicMarket
Sold by: D&K Market
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Ships from and sold by StarBunch.
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SynergyLabs SHED-X Dermaplex Shed Control Nutritional Supplement $12.24
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Words that start with chondrocra | Words starting with chondrocra
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We stayed here for three nights as part of our... - Review of Basecamp Masai Mara - TripAdvisor
We stayed here for three nights as part of our... - Review of Basecamp Masai Mara
Ranked #12 of 145 Specialty Lodging in Maasai Mara National Reserve
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Civil War Maps, History, Cobb County | Library of Congress
Results: 1-12 of 12 | Refined by: Part of: Civil War Maps Remove Subject: History Remove Location: Cobb County Remove

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Lantau Trail - Wikipedia
The Lantau Trail (Chinese: 鳳凰徑), opened on 4 December 1984, is a long-distance footpath on Lantau Island in the New Territories of Hong Kong. The 70 kilometres (43 mi) trail is a loop starting and finishing in Mui Wo. The Lantau Trail has good visitor facilities along the way, and the route is well marked. There are information boards and maps at junctions between each stage. Distance Posts 500 metres apart help hikers know exactly where they are. At each turning, route signs give clear instructions about directions, place names, and the distances and times for hiking between various places.[1]
Approach to Sunset Peak.
View of Buddha from near the Ngong Ping 360 station.
2 Trail rerouting at Ngong Ping (Sections 4 and 5)
3 Trail closing at Yi O (Section 7) and related controversy
4 Phoenix Walkathon
The Lantau Trail has 12 stages.[1] There are distance posts, numbered 000 through 140, every 500m:
1 Mui Wo → Nam Shan 2.5 0.75 000 005
2 Nam Shan → Pak Kung Au 6.5 2.75 005 018
3 Pak Kung Au → Ngong Ping 360 6.0 2.75 018 030
4 Ngong Ping 360 → Sham Wat Road1 2.5 1.25 030/031 034/035
5 Sham Wat Road → Man Cheung Po 7.5 2.75 034/035 050
6 Man Cheung Po → Tai O 2.5 1.0 050 055
7 Tai O → Kau Ling Chung 10.5 3.0 055 076
8 Kau Ling Chung → Shek Pik 5.5 1.5 076 087
9 Shek Pik → Shui Hau 6.5 2.0 087 100
10 Shui Hau → Tung Chung Road 6.5 2.0 100 112/113
11 Tung Chung Road → Pui O 4.5 1.25 112/113 122
12 Pui O → Mui Wo 9.0 3.0 122 140
1 Path is rerouted. The Section 4/5 changeover appears now to occur very close to the Ngong Ping 360 cable lift. Section 5 for the most part follows Ngong Ping Road from Ngong Ping 360 to the start of Section 6. As of December 2013, Google Maps does not have the correct route in its database.
2 Path is partially closed. An alternative route has been suggested.
Trail rerouting at Ngong Ping (Sections 4 and 5)[edit]
The current routing leaves it unclear if the Section 4/5 changeover is near distance post 027 or distance post 030. The previous changeover was at 027. For easiest access to/from Ngong Ping and Ngong Ping 360, follow the trail to distance post 030. Once at the cable car station, follow the pedestrian shopping mall in the direction of the Tian Tan Buddha for around 200m, watching on the right for a poorly displayed Lantau Trail sign pointing hikers downhill along Ngong Ping Road. The new Section 5 follows the road all the way to Section 6.
Trail closing at Yi O (Section 7) and related controversy[edit]
The trail crosses private land at Yi O Village[2] and access is officially closed (as verified in December 2013).
Along the trail is posted the following message:
Farmland rehabilitation within private lots in Yi O Kau Tsuen and Yi O San Tsuen is in progress. The land owners do not allow unauthorised access to those villages. The affected sections of Lantau Trail Section 7 passing through those villages will be diverted. Visitors who wish to go to Fan Lau or Kau Liu Chung are advised to choose alternative route as shown on the map below.[3]
The closing applies approximately to the part of Section 7 between distance posts 062 and 065 only, but the alternate route skips a length of trail starting from around distance post 059 and ending around distance post 073. Portions of the alternate route are not available on Google maps as of December 2013. The intermediate distance posts in the closed section appear to have been removed. There is currently no sign indicating when (or if) the original part of Section 7 will be restored.
One can find the approximate original route by turning left at the end of the paved path, following the trail/dirt road, and then staying to the left of the organic produce farm. However use of this route, as a separate sign indicates, will be considered trespassing—those who choose to find the original route should be mindful about causing disruptions. The suggested alternate route leaves the Lantau Trail right after distance post 059 (and immediately before Na Ying Kok campsite) and rejoins the trail near distance post 073. Substantial clearing work for an organic farm has occurred since 2010, so finding the trail may be difficult.,[4]
The trail closing has, as of December 2013, generated considerable political controversy. The developer of the 9-hectare organic farm, Andrew Lam Siu-lo, is being investigated for having cleared ecologically sensitive land by burning and for having brought heavy construction machinery into a protected Hong Kong country park. The Yi O village area has protected wetland area and is one of the few habitats of Hong Kong's endemic and rare Romer's tree frog.[5] Lam was a top advisor to Hong Kong Chief Executive CY Leung's 2012 campaign.[5] Rerouting of the trail appears to have been unnecessary and one might reasonably point to Mr. Lam's motivation in attempting to keep the public away from Yi O. Other than some recent development, Yi O appears to be an all but abandoned village,[5] having lost its population long ago, and therefore restrictions against "trespassing" on village property might only make sense in the context of Mr. Lam's development project.
Phoenix Walkathon[edit]
The Phoenix Walkathon was previously held by the Hong Kong Ecotoursism Society along the 70-km Lantau Trail every year, although it was cancelled in the early 2000s.[6]
^ a b Agriculture, Fisheries and Conservation Department – Lantau Trail Country and Marine Parks Authority Agriculture
^ "Minutes of 1033rd Meeting of the Town Planning Board held on 10.5.2013" (PDF). 10 May 2013. Retrieved 12 December 2013.
^ (See photo on right)
^ A private video and slideshow record of Section 7 (as posted [url=https://www.youtube.com/watch?v=q-MCtATkQ1Y here]) from 2010 includes a hike along the closed section of the trail, "Lantau Trail 7 (Tai O – Kau Ling Chung/Fan Lau) 6 February 2010". Retrieved 12 December 2013.
^ a b c South China Morning Post "Work on West Lantau farm project hits legal snag". 9 December 2013. Retrieved 12 December 2013.
^ "Lantau Trail Race/Phoenix Walkathon". 4 January 2010. Retrieved 12 December 2014.
Wikimedia Commons has media related to Lantau Trail.
Country and Marine Parks Authority: Lantau Trail
Video record of hike on Section 7 prior to the farm development
Coordinates: 22°14′58″N 113°55′41″E / 22.2495°N 113.9280°E / 22.2495; 113.9280
Retrieved from "https://en.wikipedia.org/w/index.php?title=Lantau_Trail&oldid=857995520"
This page was last edited on 4 September 2018, at 11:26 (UTC).

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History repeats itself as Bernabeu faithful hail Iniesta | Daily Mail Online
Published: 17:59 EST, 21 November 2015 | Updated: 17:59 EST, 21 November 2015
MADRID, Nov 21 (Reuters) - Almost exactly 10 years after it first occurred the previously unthinkable happened again on Saturday -- Real Madrid fans got to their feet to applaud a Barcelona player during the 'Clasico' even though their team were losing.
Instead of the usual vitriol Barca players have had hurled at them at the Bernabeu stadium, when captain Andres Iniesta was substituted near the end of their 4-0 La Liga victory many of the Real faithful stood and clapped him off.
Iniesta had offered up a masterclass of creative midfield play, capped with a stunning strike into the top corner to make it 3-0 shortly after halftime.
Ronaldinho was given a similar reception in a La Liga game at Real's giant arena on Nov. 19, 2005, when the Brazilian forward netted two superb goals in Barca's 3-0 success and the home fans stood to applaud.
It may have helped that Iniesta is a hero in Spain for the goal that won the 2010 World Cup but it nonetheless underlined the brilliance of the 31-year-old's performance that Real fans again cast aside their hatred for their rivals for a moment.
Iniesta made his 'Clasico' debut a year before Ronaldinho's double and has featured in 32 Real-Barca games, the most of any active player from either side.
He has won 14, drawn eight and lost 10 and Saturday's goal was his third against the Madrid side.
"He is part of our world heritage," Barca coach Luis Enrique told a news conference.
"We have the good fortune to have a unique player, who has eyes in the back of his head, at the service of the team," added the former Spain midfielder. (Editing by Ken Ferris)

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‘Digitalisation of music played a spoilsport’ | chandigarh | Hindustan Times
‘Digitalisation of music played a spoilsport’
In our latest series, we catch up with homebred celebs who have been there, done that and stepped away from the spotlight. This week, Punjabi folk singer Pammi Bai spills the beans on his missing presence; says he has been keeping busy with live shows.
chandigarh Updated: May 03, 2013 10:07 IST
Pammi Bai, 49, has been popular for two things: his infectious laughter and his genre of Punjabi folk music. From village Jakhepal in district Sangrur, he is one singer who has neither allowed western beats dilute his music nor vulgarity touch his songs. He has been equally famous for his colourful attires during live-wire performances on stage.
But Pammi Bai, since a long time, has not come out with an album. We talk to him about the reasons behind the same.
Last chartbuster: His last music album Punjabiyan Di Ho Gayi Balle Balle was released in 2011 and its title song was a big hit, especially amongst the Punjabi diaspora, since the video of the song also featured Punjabis from across the world portraying their life abroad.
And, then the pause: The dip in the sale of CDs and the digitalisation of Punjabi music played a spoilsport when it comes to the singer’s enthusiasm for music albums. “The sale of Punjabi music is zero, all thanks to piracy and easy availability of music online. Even the audience these days are only interested in watching songs on television. The music companies too are responsible for changing the trend; instead of paying good singers for their work and offering royalty, these are exploiting aspiring singers by taking money from them to launch and market them. All this has turned me off. I feel that the golden era of Punjabi music has ended.”
Meanwhile: In the past two years, Pammi Bai has concentrated on live shows, says he, “I do a lot of live shows, because thankfully, people still like to hear Punjabi folk music and I get a lot of offers for live singing. I am also planning on working on a Punjabi film script, which will deal with a meaningful subject.”
Comeback plan: The singer’s fans will soon get to hear their him again, nods Pammi Bai, “I have just finalised my new song - one song in a multi-singer album. The title of the album is named after my song, Teri Akh, and the album should be out in a month.”
* Dance with Pammi Bai
* Nach Nach Pauni Dhammal
* Giddha Malwaian Da
* Nachde Punjabi
* Putt Punjabi — Son of Punjab (2006)
* Dhol Te Dhamaalan (2007)
First Published: May 03, 2013 10:05 IST

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Amazon Best Sellers Rank: #554,305 Paid in MP3 Albums (See Top 100 Paid in MP3 Albums)
The remarkable Mr. Reed
Format:Audio CD As far as I know this is the first Amazon review of any of Mike Reed's CDs. He deserves better. He has already produced an excellent body of work and presents concerts in the Chicago area of other musicians whose work he admires (his web site states that he works in or presents 150+ shows a year). He is a paragon of that spirit of communal musical endeavor and research which seems to define the current Chicago scene (or so it appears from Portland, OR).As far as I can tell, MR lead's two main groupings Loose Assembly (I promise a review of their The Speed of Change in a few days) and People, Places & Things.The latter is the grouping on this CD and consists of a quartet comprised ofMike Reed- drums, piano and some of the compositionsTim Haldeman- tenor sax and pianoGreg Ward- alto sax and pianoJason Roebke- bass and piano.Like many of the first great generation of the AACM, Mike Reed is an historian of the music especially the musical history of Chicago. Go to his web site and you will find pictures of the Great Clifford Jordan (most underknown tenor sax player ever- if you don't have Glass Bead Games or In The World you are missing two of the essential documents of late '60s and '70s jazz), news about the Chicago scene and the state of the AACM, and about the music scene in Europe.It would seem that part of the reason for the People, Places & Things groupings was to revisit a particularly fertile earlier period of the Chicago scene."The original focus of our quartet was to investigate and reinvent some of the under-recorded, under-recognized aspects of the vibrant Chicago jazz scene circa 1954-60. On Proliferation, we brought ideas and new approaches to music of another time."MR reworks songs by John Neely (Status Quo -the first song on Blowing In From Chicago a Clifford Jordan/John Gilmore date that is a hard bop classic), by John Jenkins, Sun Ra and Wilbur Campbell among others. MR also wrote three of the compositions, "People", "Places" and "Things".The approach to the material is typified by the way they play Status Quo. Rather than just play it straight MR arranges it in sections some of which play the tune straight and some of which use it as material to create very different music. The result is a music that is respectful of a undervalued facet of the music's history yet also respect the music's original creative intent. We are talking about Gilmore and Jordan here.Mike Reed's music is one of my most enjoyable musical discoveries of recent years. He is another of the great artists on the 482 label which deserves your most careful attention. It is one of those labels that features the work of a large grouping of musicians all of whom work with each other. Like I said earlier, they constitute a research community. I have a Listmania list called "Independence and the Chicago Improv Scene:482 Music" which might serve you for an introduction to the label. Better yet go to their site and look around at all the wonderful stuff. And while you are cyberspacing, go back to Mike Reed's site and find his recipe for Shrimp Etouffe. I tried it tonight and my two little girls (and future food critics) liked it very much. What can I tell you? MR is a renaissance man. Read more ›


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The 10 Best Hotels Near Smoky Mountain Angler, Gatlinburg
Best Hotels Near Smoky Mountain Angler, Gatlinburg, Tennessee
United States›Tennessee (TN)›Sevier County›Gatlinburg›Gatlinburg Hotels› Hotels near Smoky Mountain Angler
469 Brookside Village Way, Gatlinburg, TN 37738 Read Reviews of Smoky Mountain Angler
Clear all Your selections $45 - $1,000
SPONSORED Mountain Shadows Log Home ResortSpecial OfferSmoky Mtns Summer Savings 1901 E Parkway, Gatlinburg, TN 377382.6 miles from Smoky Mountain Angler 97 Reviews#55 of 84 hotels in Gatlinburg06/20/2016 “Mountain Resort”05/18/2016 “Nice Setting”BudgetPoolFree ParkingSpecial Offer: Smoky Mtns Summer SavingsCall us for Best Summer Rates! Book Direct to get Savings... Read more SlideshowShow Prices Check In Check Out Show Prices
The hotel you picked You might also like these Gatlinburg hotels Brookside ResortOffers & AnnouncementsPackage Deal 463 East Parkway, Gatlinburg, TN 377380.1 miles from Smoky Mountain Angler 754 Reviews#32 of 84 hotels in Gatlinburg07/20/2016 “Not bad but not great”07/20/2016 “Great Location w/ Upgrades Underway”Free BreakfastMid-rangePool SlideshowShow Prices Check In Check Out Show Prices
Roaring Fork Motel & Cottages124 Roaring Fork Road, Gatlinburg, TN 37738 0.1 miles from Smoky Mountain Angler 32 Reviews#53 of 84 hotels in Gatlinburg09/14/2015 “weekend getaway”07/19/2016 “A diamond in the rough”BudgetFree Parking Show Prices Check In Check Out Show Prices
Country Town N' Suites523 East Parkway, I-40 Exit 407 Highway 321, Gatlinburg, TN 377380.1 miles from Smoky Mountain Angler 134 Reviews#56 of 84 hotels in Gatlinburg07/21/2016 “For the money”07/13/2016 “Small but Nice”BudgetFree ParkingPets Allowed Show Prices Check In Check Out Show Prices
Rainbow Motel390 E. Parkway, Gatlinburg, TN 377380.1 miles from Smoky Mountain Angler 20 Reviews#80 of 84 hotels in Gatlinburg03/05/2015 “What a scum bucket”05/24/2012 “Bugs will carry you away” Show Prices Check In Check Out Show Prices
Rocky River Motel544 E Parkway, Gatlinburg, TN 377380.1 miles from Smoky Mountain AnglerBe the first to review this hotel Show Prices Check In Check Out Show Prices
Carr's Northside Cottages & Motel421 Laurel Road West, P.O. Box 728, Gatlinburg, TN 377380.2 miles from Smoky Mountain Angler 378 Reviews#23 of 84 hotels in Gatlinburg07/24/2016 “Love this place!”07/23/2016 “Charming”Mid-rangePoolFree Parking Show Prices Check In Check Out Show Prices
Sleep Inn & SuitesSpecial OfferChoice Privileges Points 335 East Parkway, Gatlinburg, TN 377380.2 miles from Smoky Mountain Angler 406 Reviews#41 of 84 hotels in Gatlinburg07/19/2016 “Vacation ”07/03/2016 “Overall stay”Free BreakfastBudgetPool SlideshowShow Prices Check In Check Out Show Prices
Gatlinburg Village Motel366 E. Parkway, Gatlinburg, TN 377380.2 miles from Smoky Mountain Angler 5 Reviews#67 of 84 hotels in Gatlinburg06/09/2010 “Perfect location easy walk to everything”01/02/2007 “What A Joke!!!!!!” Show Prices Check In Check Out Show Prices
Red Carpet Inn of Gatlinburg349 E. Parkway, Gatlinburg, TN 377380.2 miles from Smoky Mountain Angler 51 Reviews#76 of 84 hotels in Gatlinburg04/15/2016 “Very good, clean, no smell!”11/14/2015 “DONT GO.”BudgetPoolFree Parking Show Prices Check In Check Out Show Prices
Creekside Inn of the Smokies239 Sycamore Ln, Gatlinburg, TN 377380.3 miles from Smoky Mountain Angler 7 Reviews#64 of 84 hotels in Gatlinburg09/15/2015 “Weekend away”10/04/2014 “This Motel Is A Good Value”Free Parking Show Prices Check In Check Out Show Prices
East SideEast Parkway, Gatlinburg, TN 377380.3 miles from Smoky Mountain Angler 14 Reviews#66 of 84 hotels in Gatlinburg10/09/2015 “Bed Bugs!!!”08/15/2015 “Incredibly disappointing ” Show Prices Check In Check Out Show Prices
Parkview InnOffers & AnnouncementsBook Direct and Save! 200 East Parkway, Gatlinburg, TN 377380.4 miles from Smoky Mountain Angler 387 Reviews#71 of 84 hotels in Gatlinburg07/22/2016 “Super Cheap Stay thru Trivago”07/20/2016 “Good stay”Free BreakfastBudgetPool SlideshowShow Prices Check In Check Out Show Prices
Greystone Lodge On the River559 Parkway, Gatlinburg, TN 377380.5 miles from Smoky Mountain Angler 719 Reviews#6 of 84 hotels in Gatlinburg07/25/2016 “Best family room we've EVER had!”07/25/2016 “Vacation ”Free BreakfastMid-rangePool SlideshowShow Prices Check In Check Out Show Prices
Zoders Inn & SuitesOffers & AnnouncementsFree parking 402 Parkway, Gatlinburg, TN 37738-30080.5 miles from Smoky Mountain Angler 1,129 Reviews#12 of 84 hotels in Gatlinburg07/26/2016 “We Love Zoders Inn. ”07/26/2016 “Good hotel”Free BreakfastMid-rangePool SlideshowShow Prices Check In Check Out Show Prices
BEST WESTERN Twin IslandsSpecial OfferGET A $50 GIFT CARD 539 Parkway, Gatlinburg, TN 37738-32010.5 miles from Smoky Mountain Angler 903 Reviews#15 of 84 hotels in Gatlinburg07/26/2016 “Very impressed with this hotel”07/26/2016 “Old but peaceful”Free BreakfastMid-rangePool SlideshowShow Prices Check In Check Out Show Prices
Crossroads Inn and Suites440 Parkway, Gatlinburg, TN 37738-30080.5 miles from Smoky Mountain Angler 388 Reviews#28 of 84 hotels in Gatlinburg07/26/2016 “Go back every year!”07/20/2016 “Good hotel - Fair Price”Free BreakfastMid-rangePool Show Prices Check In Check Out Show Prices
Rocky Waters Motor Inn333 Parkway, Gatlinburg, TN 377380.5 miles from Smoky Mountain Angler 257 Reviews#42 of 84 hotels in Gatlinburg07/02/2016 “WIFI access”06/09/2016 “Nice view”BudgetPoolFree Parking Show Prices Check In Check Out Show Prices
Days Inn Gatlinburg on the RiverSpecial OfferPlan Ahead, Save 15% 304 Hemlock Street, State Route 441/321, Gatlinburg, TN 377380.5 miles from Smoky Mountain Angler 639 Reviews#45 of 84 hotels in Gatlinburg07/21/2016 “Needs TLC”07/21/2016 “Quick get away ”Free BreakfastBudgetPool SlideshowShow Prices Check In Check Out Show Prices
Terrace Inn on the Water396 Parkway, Gatlinburg, TN 377380.5 miles from Smoky Mountain Angler 43 Reviews#75 of 84 hotels in Gatlinburg10/17/2015 “Pretty bad”07/01/2016 “Worst place in Gatlinburg to stay”BudgetFree ParkingPets Allowed Show Prices Check In Check Out Show Prices
Baymont Inn & Suites Gatlinburg On The RiverSpecial OfferPlan Ahead, Save 15% 293 Parkway, Gatlinburg, TN 37738-51500.6 miles from Smoky Mountain Angler 973 Reviews#13 of 84 hotels in Gatlinburg07/26/2016 “Pretty nice!!”07/17/2016 “7-10-2016 to 7-15-2016 Stay.”Free BreakfastBudgetPool SlideshowShow Prices Check In Check Out Show Prices
Quality Inn & Suites GatlinburgSpecial OfferChoice Privileges Points 401 Hemlock Street, Gatlinburg, TN 377380.6 miles from Smoky Mountain Angler 538 Reviews#18 of 84 hotels in Gatlinburg07/24/2016 “Great Hotel!”07/20/2016 “Very nice visit”Free BreakfastBudgetPool SlideshowShow Prices Check In Check Out Show Prices
Sleepy Bear Motel820 E Parkway, Gatlinburg, TN 37738-49090.6 miles from Smoky Mountain Angler 39 Reviews#49 of 84 hotels in Gatlinburg06/12/2016 “Would stay again”08/23/2015 “Great Stay”PoolFree Parking Show Prices Check In Check Out Show Prices
Bales Motel221 Bishop Lane, Gatlinburg, TN 377380.6 miles from Smoky Mountain Angler 77 Reviews#54 of 84 hotels in Gatlinburg05/23/2016 “Deja vu all over again :-) 1st review 4 years earlier”08/24/2015 “Very reasonable, extremely nice people, HUGE ROOM!!!”PoolFree Parking Show Prices Check In Check Out Show Prices
Kingwood Inn117 Bishop Lane, Gatlinburg, TN 377380.6 miles from Smoky Mountain Angler 161 Reviews#61 of 84 hotels in Gatlinburg06/13/2016 “Outdated but Clean and comfortable”06/07/2016 “a little gem thats hidden”Free BreakfastBudgetPool Show Prices Check In Check Out Show Prices
Jack Huff's204 Cherokee Orchard Road, Gatlinburg, TN 377380.7 miles from Smoky Mountain Angler 477 Reviews#1 of 84 hotels in Gatlinburg07/26/2016 “Great motel with great prices.”07/26/2016 “7/13/16 - 7/17/16 Stay”Mid-rangePoolFree Parking Show Prices Check In Check Out Show Prices
Fairfield Inn & Suites Gatlinburg NorthSpecial OfferMember Rates 168 Parkway, Gatlinburg, TN 377380.7 miles from Smoky Mountain Angler 605 Reviews#11 of 84 hotels in Gatlinburg07/26/2016 “Comfortable”07/24/2016 “Family get away ”Free BreakfastBudgetPool SlideshowShow Prices Check In Check Out Show Prices
Mountain House Motor Inn Downtown247 Newton Lane, Gatlinburg, TN 377380.7 miles from Smoky Mountain Angler 255 Reviews#26 of 84 hotels in Gatlinburg07/26/2016 “Family weekend”07/25/2016 “better than expected.”BudgetPoolFree Parking Show Prices Check In Check Out Show Prices
Marshall's Creek Rest Motel313 Baskins Creek Rd, Gatlinburg, TN 37738-35030.7 miles from Smoky Mountain Angler 115 Reviews#31 of 84 hotels in Gatlinburg07/23/2016 “Great Service”07/18/2016 “Relived a little of my childhood...”BudgetPoolFree Parking Show Prices Check In Check Out Show Prices
Johnson's InnSpecial Price15% OFF ALL ROOMS 242 Bishop Lane, PO Box 392, Gatlinburg, TN 377380.7 miles from Smoky Mountain Angler 277 Reviews#39 of 84 hotels in Gatlinburg07/18/2016 “Great Place”05/16/2016 “Comfortable Beds”Mid-rangePoolFree Parking SlideshowShow Prices Check In Check Out Show Prices
Economy Inn & Suites208 Woliss Ln, Gatlinburg, TN 37738-35260.7 miles from Smoky Mountain Angler 39 Reviews#46 of 84 hotels in Gatlinburg07/26/2016 “A good family hotel”07/25/2016 “in town for Karate Tournament”Free BreakfastBudgetPool SlideshowShow Prices Check In Check Out Show Prices


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Conformational equilibrium of cytochrome P450 BM-3 complexed with N-palmitoylglycine: a replica exchange molecular dynamics study. - PubMed - NCBI
1 selected item: 16637647
J Am Chem Soc. 2006 May 3;128(17):5786-91.
Ravindranathan KP1, Gallicchio E, Friesner RA, McDermott AE, Levy RM.
UV-vis absorbance measurements and associated studies of cytochrome P450 BM-3 in complex with N-palmitoylglycine (NPG) indicate that a conformational change occurs in the active site of the complex where the terminal atoms of the ligand move from a site distant from the heme iron, as seen in the low temperature crystal structure to a site proximal to the heme iron at biological temperatures. We employ replica exchange molecular dynamics simulations to study this conformational change. The population of the proximal state is found to increase with temperature in agreement with UV-vis absorbance and NMR measurements. In addition to the conformations characterized by X-ray crystallography and computer modeling, this study shows that a new conformational state is significantly populated at room temperature. The observed increase in the population of conformations where the terminal atoms of NPG are proximal to the heme iron with increasing temperature indicates that the proximal state is stabilized by conformational entropy. A proposal for the origin of this entropic stabilization is provided on the basis of the structure of the newly identified state. We use the temperature weighted histogram (T-WHAM) method to characterize the transition state regions of the conformational ensemble and propose a mechanism of interconversion between these low free energy conformational states.
16637647
PMC2533527
10.1021/ja058465i
The active site of the P450 BM-3/NPG complex in (a) the low temperature x-ray conformation (PDB id 1jpz) representative of distal state where the NPG (shown in green) is distant from the heme iron, with Phe87 (shown in magenta) interposed between NPG and heme iron (shown in blue) (b) the alternative active site of the conformation predicted by Jovanovic et al. representative of the proximal state where Phe87 has changed its rotameric state to allow NPG to approach the heme iron.
Conformational equilibrium of cytochrome P450 BM-3 complexed with N-Palmitoylglycine: A replica exchange molecular dynamics study
J Am Chem Soc. ;128(17):5786-5791.
The chemical structure of N-palmitoylglycine. The terminal carbon atom that is close to the heme iron is labeled by ω. The sites which undergo hydroxylation are labeled as ω–1, ω–2 and ω–3.
The population distribution of conformations of P450 BM-3/NPG complex as a function of ω–1-Fe distance at temperatures 260 K (solid line), 302 K (dashed line) and 318 K (dotted line). The arrows indicate the values of the ω–1-Fe distance in the x-ray crystal structure (1jpz) and the conformation modeled by Jovanovic et al. At 260 K most of the population is concentrated in the peak corresponding to the distal state. At 302 K population peaks corresponding to both proximal and distal states are seen. At 318 K the proximal state is the most populated.
The population as a function of temperature p(T) corresponding to the conformations in which ligand is proximal to the heme iron (obtained by integration of the population distribution from along the ω–1-Fe distance coordinate between 0 Å to 6.5 Å ). The proximal state population increases monotonically with temperature indicating that the proximal state is stabilized by conformational entropy at temperatures greater than at least 268 K. This is borne out by the expression for the conformational entropy difference between the proximal and the distal states, ΔS = k ln[p/(1−p)]+{kT/[p(1−p)]}∂p/∂p, where the second term is positive and the first term is positive for T >268 K (p(T) >1/2).
The population distributions at 302 K of P450 BM-3/NPG conformations as a function of (a) the ω–1-Fe distance and the χ1 angle of Phe87 and (b) the ω–1-Fe distance and the χ2 angle of Phe87. The coordinates corresponding to the x-ray crystal conformation and the proximal state conformation predicted by Jovanovic et al. are indicated by a cross and a circle respectively. The distal state, the proximal locked ligand and proximal free ligand states are indicated. Contours are drawn at 1×10−3, 1×10−2, 2.5×10−2, 5×10−2 and 1×10−1 fractional population.
Active site of the P450 BM-3/NPG complex in a representative proximal free ligand conformation. Note that in this conformation not only has the side chain Phe87 (shown in magenta) changed its rotameric state to allow NPG (shown in green) to approach the heme iron (shown in blue), but also Phe87 is oriented so as to give NPG the ability to move more freely (as compared to the the proximal state conformation predicted by Jovanovic et. al.) to and away from the heme.
Palmitic Acids/chemistry*
R01 GM030580-24/GM/NIGMS NIH HHS/United States
GM40526/GM/NIGMS NIH HHS/United States
R01 GM040526/GM/NIGMS NIH HHS/United States

value: This website is part of the United States National Library of Medicine , a branch of the National Institutes of Health . It is approved and funded by the government of the United States.


text:
Apartments Pod Kotlom, Vysoké Tatry (with photos & reviews) | Booking.com
Apartments Pod Kotlom (Apartment), Vysoké Tatry (Slovakia) Deals
Apartments Apartments Pod Kotlom
Bytovy dom c. 9, Nová Polianka, 949 01 Vysoké Tatry, Slovakia – Great location - show map
It was very clean, quiet, with a great view towards the mountain. We really enjoyed our stay. Thank You
Popa Hungary
The apartment was renovated and clean. Good value for money
The place is clean. Not far from the hiking trails. Accepted our dog.
Great location, good cooking facilities & nice shower
Nice small apartment with balcony and nice view. Newly repaired. Nice location. Not far away from Štrbské Pleso. Accepts dogs for free.
It is a quiet place near the nature. Perfect as a basis of trips.
We liked the location, the area felt safe, we found nearby local shops (about 10min driving,there might be others closer too), the view outside the house was spectacular. The flat has everything we needed. we also could park cars.
Super clean!!! Newly refurbished! The room is not huge but for the money it's absolutely great deal! The host was great (I received better service than in five star hotel). She helped way beyond her responsibilities with everything. Probably the best value for money in Tatras! Great location - right below the highest peak of Tatras - Gerlach - and right next to a tram stop. I really enjoyed my stay.
I liked the cleanliness of the apartment and it had all the equipments we needed for our stay. The service lady was friendly. The location was nice and quiet and it was very close to the TEZ station. Satisfied! :)
Kathush Hungary
Lokalizacja jest bardzo dobra. Lekko na wzgórzu z pięknymi widokami, a do Strbskiego plesa jest rzut beretem. Łatwo dojechać. Mieszkanko niedawno remontowane, czysciutkie, lozko wygodne :) Wysoki parter.
Edyta Hungary
Lock in a great price for Apartments Pod Kotlom – rated 8.9 by recent guests!
“It was very clean, quiet, with a great view towards the mountain. We really enjoyed our stay. Thank You”
“The apartment was renovated and clean. Good value for money”
“The place is clean. Not far from the hiking trails. Accepted our dog.”
“Great location, good cooking facilities & nice shower”
“Nice small apartment with balcony and nice view. Newly repaired. Nice location. Not far away from Štrbské Pleso. Accepts dogs for free.”
“It is a quiet place near the nature. Perfect as a basis of trips.”
“We liked the location, the area felt safe, we found nearby local shops (about 10min driving,there might be others closer too), the view outside the house was spectacular.”
“Super clean!!! Newly refurbished! The room is not huge but for the money it's absolutely great deal! The host was great (I received better service than in five star hotel).”
“I liked the cleanliness of the apartment and it had all the equipments we needed for our stay. The service lady was friendly. The location was nice and quiet and it was very close to the TEZ station.”
“Lokalizacja jest bardzo dobra. Lekko na wzgórzu z pięknymi widokami, a do Strbskiego plesa jest rzut beretem. Łatwo dojechać.”
Located in Vysoké Tatry, Apartments Pod Kotlom has mountain views and free WiFi, 2.6 miles from Gerlach peak and 10 miles from Lomnicky peak.
The accommodations come with a flat-screen TV and a private bathroom with shower while the kitchenette has a microwave, a fridge and a stovetop. Some units have a seating area and/or a balcony.
Starý Smokovec-Hrebienok is 5 miles from the apartment, while Jakubkova Luka 2 is 5 miles from the property. The nearest airport is Poprad-Tatry Airport, 12 miles from Apartments Pod Kotlom.
Apartments Pod Kotlom has been welcoming Booking.com guests since Jul 14, 2016
7 properties in Vysoké Tatry like Apartments Pod Kotlom were booked in the last 12 hours
“We liked the location, the area felt safe, we found nearby local shops (about 10min driving,there might be others closer too), the view outside the house was sp...”
“Super clean!!! Newly refurbished! The room is not huge but for the money it's absolutely great deal! The host was great (I received better service than in f...”
Facilities of Apartments Pod Kotlom Great facilities! Review score, 8.8
House rules Apartments Pod Kotlom takes special requests – add in the next step!
Please inform Apartments Pod Kotlom of your expected arrival time in advance. You can use the Special Requests box when booking, or contact the property directly using the contact details in your confirmation.
All reviewers Families (70) Couples (89) Groups of friends (17) Solo travelers (16) Business travelers (1)
All review scores Awesome: 9+ (147) Good: 7 – 9 (80) Okay: 5 – 7 (16) Poor: 3 – 5 (0) Very Poor: 1 – 3 (2)
44 people are currently looking for a place in Vysoké Tatry
“Great location, good cooking facilities & nice shower ”
“We liked the location, the area felt safe, we found nearby local shops (about 10min driving,there might be others closer too), the view outside the house was spectacular. The flat has everything we needed. we also could park cars.”
“Super clean!!! Newly refurbished! The room is not huge but for the money it's absolutely great deal! The host was great (I received better service than in five star hotel). She helped way beyond her responsibilities with everything. Probably the best value for money in Tatras! Great location - right below the highest peak of Tatras - Gerlach - and right next to a tram stop. I really enjoyed my stay.”
“I liked the cleanliness of the apartment and it had all the equipments we needed for our stay. The service lady was friendly. The location was nice and quiet and it was very close to the TEZ station. Satisfied! :)”
“Lokalizacja jest bardzo dobra. Lekko na wzgórzu z pięknymi widokami, a do Strbskiego plesa jest rzut beretem. Łatwo dojechać. Mieszkanko niedawno remontowane, czysciutkie, lozko wygodne :) Wysoki parter.”
See all guest reviews for Apartments Pod Kotlom
Newest Reviews for Apartments Pod Kotlom
The wifi could be more faster😅.
Bed is very comfort.
We didnt't like Nova Polianka, because it was too quiet and scary at night, we could even hear animal sounds at night.
The partition walls are thin, we could hear our neighbours too well. There are no amenities (such as a grocery shop, restaurant, ATM) in Nova Polianka.
It was pleasanr overall.
There was a weird smell coming from the bathroom. The walls were very very thin so we could hear everything through the walls which kept us up at night. The bed was also very uncomfortable
The only thing I did not like is not comfortable bed (thin mattress on a pallet).
“Quiet place near the nature.”
The look on mountain is beautiful. Thanks.
There was only a little trash bin in the bathroom.
The service lady did not speak a word of english
“I just enjoeyd it!”
Nothing. Perhaps availability of rental bikes (ideally electric bikes) in the location would make it absolute superb. But in general, rental bikes are not easy to find anywhere.
“Not bad, not WOW”
We stayed at the ground floor. If anyone is upstairs from you, you will hear his/her footsteps lipe guns, as the floor upstaris is old and noisy. AlsopPretty hard to park nearby.
Clean place, nice hostess, great surroundings!
984230|1,981380|1,965970,974320,978240,984230|3,963920,977230|2,964350,974800,965830,973750,984900,982340,972950,981000,983150,984230,975150,976730,977160|2,963470,981380,981510,979800,835220,758330,950390,978880,971430

value: This website is a Dutch online travel agency for lodging reservations & other travel products, and a subsidiary of Booking Holdings. It is headquartered in Amsterdam.The website has over 28 million listings.


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Benoit Gaillat's followers | Scribd
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Nerman_O [Author] - PubMed - NCBI
Create RSSRSS SettingsSearch: Nerman_O [Author]Number of items displayed:510152050100Feed name:Create RSSCreate alertAdvancedHelp
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Select item 268103111.Statistical evaluation of methods for identification of differentially abundant genes in comparative metagenomics.Jonsson V, Österlund T, Nerman O, Kristiansson E.BMC Genomics. 2016 Jan 25;17:78. doi: 10.1186/s12864-016-2386-y.PMID: 26810311 Free PMC ArticleSimilar articles Select item 263162262.Upper Respiratory Infections and MRI Activity in Relapsing-Remitting Multiple Sclerosis.Kneider M, Lisovskaja V, Lycke J, Malmeström C, Jakobsen JK, Nerman O, Andersen O.Neuroepidemiology. 2015;45(2):83-9. doi: 10.1159/000437371. Epub 2015 Aug 29.PMID: 26316226 Similar articles Select item 257125413.The outcome spectrum of multiple sclerosis: disability, mortality, and a cluster of predictors from onset.Tedeholm H, Skoog B, Lisovskaja V, Runmarker B, Nerman O, Andersen O.J Neurol. 2015 May;262(5):1148-63. doi: 10.1007/s00415-015-7674-y. Epub 2015 Feb 26.PMID: 25712541 Similar articles Select item 253254604.Sleep apnea-related risk of motor vehicle accidents is reduced by continuous positive airway pressure: Swedish Traffic Accident Registry data.Karimi M, Hedner J, Häbel H, Nerman O, Grote L.Sleep. 2015 Mar 1;38(3):341-9. doi: 10.5665/sleep.4486.PMID: 25325460 Free PMC ArticleSimilar articles Select item 252857695.The association between HbA1c, fasting glucose, 1-hour glucose and 2-hour glucose during an oral glucose tolerance test and cardiovascular disease in individuals with elevated risk for diabetes.Lind M, Tuomilehto J, Uusitupa M, Nerman O, Eriksson J, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Peltonen M, Pivodic A, Lindström J.PLoS One. 2014 Oct 6;9(10):e109506. doi: 10.1371/journal.pone.0109506. eCollection 2014.PMID: 25285769 Free PMC ArticleSimilar articles Select item 248117096.Changes in HbA1c and frequency of measuring HbA1c and adjusting glucose-lowering medications in the 10 years following diagnosis of type 2 diabetes: a population-based study in the UK.Lind M, Pivodic A, Cea-Soriano L, Nerman O, Pehrsson NG, Garcia-Rodriguez LA.Diabetologia. 2014 Aug;57(8):1586-94. doi: 10.1007/s00125-014-3250-8. Epub 2014 May 9.PMID: 24811709 Similar articles Select item 234449677.A novel method for cross-species gene expression analysis.Kristiansson E, Österlund T, Gunnarsson L, Arne G, Larsson DG, Nerman O.BMC Bioinformatics. 2013 Feb 27;14:70. doi: 10.1186/1471-2105-14-70.PMID: 23444967 Free PMC ArticleSimilar articles Select item 231247898.Time to secondary progression in patients with multiple sclerosis who were treated with first generation immunomodulating drugs.Tedeholm H, Lycke J, Skoog B, Lisovskaja V, Hillert J, Dahle C, Fagius J, Fredrikson S, Landtblom AM, Malmeström C, Martin C, Piehl F, Runmarker B, Stawiarz L, Vrethem M, Nerman O, Andersen O.Mult Scler. 2013 May;19(6):765-74. doi: 10.1177/1352458512463764. Epub 2012 Nov 1.PMID: 23124789 Free PMC ArticleSimilar articles Select item 226998619.Transcriptional and metabolic data integration and modeling for identification of active pathways.Jauhiainen A, Nerman O, Michailidis G, Jörnsten R.Biostatistics. 2012 Sep;13(4):748-61. doi: 10.1093/biostatistics/kxs016. Epub 2012 Jun 14.PMID: 22699861 Free PMC ArticleSimilar articles Select item 2249674510.Distinct cytoplasmic and nuclear functions of the stress induced protein DDIT3/CHOP/GADD153.Jauhiainen A, Thomsen C, Strömbom L, Grundevik P, Andersson C, Danielsson A, Andersson MK, Nerman O, Rörkvist L, Ståhlberg A, Åman P.PLoS One. 2012;7(4):e33208. doi: 10.1371/journal.pone.0033208. Epub 2012 Apr 9.PMID: 22496745 Free PMC ArticleSimilar articles Select item 2106410311.Expression profiling of GIST: CD133 is associated with KIT exon 11 mutations, gastric location and poor prognosis.Arne G, Kristiansson E, Nerman O, Kindblom LG, Ahlman H, Nilsson B, Nilsson O.Int J Cancer. 2011 Sep 1;129(5):1149-61. doi: 10.1002/ijc.25755. Epub 2011 Jan 7.PMID: 21064103 Free ArticleSimilar articles Select item 1934135312.Testing of chromosomal clumping of gene properties.Fernandez-Ricaud L, Dalevi D, Blomberg A, Nerman O.Stat Appl Genet Mol Biol. 2009;8:Article 19. doi: 10.2202/1544-6115.1428. Epub 2009 Feb 26.PMID: 19341353 Similar articles Select item 1928461613.Genetic basis of arsenite and cadmium tolerance in Saccharomyces cerevisiae.Thorsen M, Perrone GG, Kristiansson E, Traini M, Ye T, Dawes IW, Nerman O, Tamás MJ.BMC Genomics. 2009 Mar 12;10:105. doi: 10.1186/1471-2164-10-105.PMID: 19284616 Free PMC ArticleSimilar articles Select item 1925845114.Evolutionary forces act on promoter length: identification of enriched cis-regulatory elements.Kristiansson E, Thorsen M, Tamás MJ, Nerman O.Mol Biol Evol. 2009 Jun;26(6):1299-307. doi: 10.1093/molbev/msp040. Epub 2009 Mar 3.PMID: 19258451 Free ArticleSimilar articles Select item 1922344015.mRNA stability changes precede changes in steady-state mRNA amounts during hyperosmotic stress.Molin C, Jauhiainen A, Warringer J, Nerman O, Sunnerhagen P.RNA. 2009 Apr;15(4):600-14. doi: 10.1261/rna.1403509. Epub 2009 Feb 17.PMID: 19223440 Free PMC ArticleSimilar articles Select item 1875451316.Evolutionary conservation of human drug targets in organisms used for environmental risk assessments.Gunnarsson L, Jauhiainen A, Kristiansson E, Nerman O, Larsson DG.Environ Sci Technol. 2008 Aug 1;42(15):5807-13.PMID: 18754513 Similar articles Select item 1798571017.[Systems biology can radically change health care. Basis for individualized prediction, prevention and treatment].Benson M, Cardell LO, Hohmann S, Jirstrand M, Langston M, Mobini R, Nerman O.Lakartidningen. 2007 Oct 17-23;104(42):3037-41. Review. Swedish. No abstract available. PMID: 17985710 Similar articles Select item 1793780718.Weighted analysis of general microarray experiments.Sjögren A, Kristiansson E, Rudemo M, Nerman O.BMC Bioinformatics. 2007 Oct 15;8:387.PMID: 17937807 Free PMC ArticleSimilar articles Select item 1755555919.Sensitive and robust gene expression changes in fish exposed to estrogen--a microarray approach.Gunnarsson L, Kristiansson E, Förlin L, Nerman O, Larsson DG.BMC Genomics. 2007 Jun 7;8:149.PMID: 17555559 Free PMC ArticleSimilar articles Select item 1732749220.Quantitative transcriptome, proteome, and sulfur metabolite profiling of the Saccharomyces cerevisiae response to arsenite.Thorsen M, Lagniel G, Kristiansson E, Junot C, Nerman O, Labarre J, Tamás MJ.Physiol Genomics. 2007 Jun 19;30(1):35-43. Epub 2007 Feb 27.PMID: 17327492 Free ArticleSimilar articles Per page: 20Items per page5102050100200
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Home Sale Details and Property Taxes for 4412 Willow Woods Dr, Annandale VA, 22003
$445,000 / Feb 22, 2013
4412 Willow Woods Dr, Annandale, VA 22003
Buyer(s)Tae Kim
Seller(s)Dae Hyo Jung
Seller Agent, BrokerDaljae Lee, Fairfax Realty Inc.
Buyer Agent, BrokerKil Lee, RE/MAX Allegiance
Sale History for 4412 Willow Woods Dr, Annandale, VA 22003
Matthew S Shimko
Dae Hyo Jung
Dae H Jung
Dodge Co-trustee,maurice Sproul
Steven Allen Waller Co-tr
Tax Assessment(s) for 4412 Willow Woods Dr, Annandale, VA 22003
Recently Sold Homes in 22003

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