Williamson indicated that if a Scream 5 were to be made, it would be a continuation of the story of the characters who lived through Scream 4 but that Scream 4 would not include any cliffhangers that led into the potential sequel.
Williamson indikerade att om en femte film skulle göras skulle det vara en fortsättning av storyn om karaktärerna som överlevde Scream 4, men att Scream 4 inte skulle innehålla några cliffhangers som ledde till potentiella uppföljare.