Tests with the prototype commenced in 1994, and Talgo 350 trains have been operating at a top commercial speed of 330 km/h on the Madrid-Barcelona and Madrid-Valladolid lines since 22 December 2007.
Talgo 350 har varit i kommersiell drift i hastigheter upp till 330 km/h på linjerna Madrid-Barcelona och Madrid-Valladolid sedan den 22 december 2007.