In 1901 Quiroga published his first book, Los Arrecifes de Coral (Coral Reefs), but the achievement was overshadowed by the deaths of two of his siblings, Prudencio and Pastora, who were victims of typhoid fever in Chaco.
År 1901 hade Quiroga publicerat sin första bok, Los Arrecifes de Coral (”Korallreven”), men denna prestation överskuggades av två dödsfall; hans båda bröder, Prudencio och Pastora, föll i Gran Chaco offer för tyfoidfeber.