The availability of small and relatively inexpensive nitrogen lasers operating at 337 nm wavelength and the first commercial instruments introduced in the early 1990s brought MALDI to an increasing number of researchers.
由于337纳米波长运行的小型和相对廉价的氮激光出现，在1990年代初期推出的第一款商业仪器把MALDI仪器带给了越来越多的研究人员。