Due to its then unique ability to derivitize otherwise inert substrates Barton used this reaction extensively in the 1960s to create a number of unnatural steroid analogues.
由于其独特的衍生其他惰性底物的能力，巴顿在20世纪60年代广泛使用这种反应来制造许多非天然的类固醇类似物。