On the road at Lincoln Financial Field, the Indianapolis Colts played a NFC opponent in the Philadelphia Eagles for the first time since the 2006 season.  The game did not start well for the Colts who allowed the Eagles to score a quick touchdown on only 3 plays covering 72&#160;yards.  A Peyton Manning interception caused more concern as the Colts now found themselves under the gun halfway through the first quarter.  Two key defensive stops allowed the Eagles to only score two field goals making it a 13-0 Eagles lead heading into the second quarter.  A touchdown pass from Manning to Jacob Tamme allowed the Colts to get back into the game trailing the Eagles only 13-7.  A Philadelphia field goal from David Akers added to the lead, however the Colts continued chipping away.  A hard hit on wide receiver Austin Collie, who was returning from injury that week, caused a 10&#8209;minute delay in the game in which he was strapped to a stripper and taken to a nearby hospital, where he was diagnosed with a concussion.  The Colts, playing with passion, drove down the field and scored a touchdown and field goal within the final two minutes of the half, giving them a 17-16 lead at halftime.  The offensive production seen by the Colts in the second quarter was nowhere to be found in the third.  The Colts began the third quarter with two three-and-outs while the Eagles got the lead back with a 44-yard field goal halfway through the quarter.  Going into the fourth quarter, the Eagles were driving down into scoring position where a 1-yard run by Michael Vick gave the Eagles a 26-17 lead over the Colts.  A continued lack of offensive production gave the Eagles the ball back and time to milk the clock.  The Colts received the ball back with less than four minutes remaining in the game, trailing by two scores and drove down to score a touchdown.  Jim Caldwell elected to kick the ball away to Philadelphia with 1:50 left, a first down and a defensive stop gave the Colts the ball back with less than 0:50&#160;seconds in the game.  After driving to midfield, Manning threw his second interception of the game and sealed the Indianapolis Colts third loss of the season.
How many interceptions did Manning have?
2