meta_pmid int64 | meta_language string | meta_mesh_ids list | meta_mesh_terms list | meta_pubdate_year string | meta_pubdate_month string | text string |
|---|---|---|---|---|---|---|
9,633,662 | eng | [
"D000818",
"D001419",
"Q000302",
"D015169",
"D018857",
"D006358",
"D006863",
"D008460",
"Q000382",
"D013552",
"Q000382",
"D013997"
] | [
"Animals",
"Bacteria",
"Colony Count, Microbial",
"Food Packaging",
"Hot Temperature",
"Hydrogen-Ion Concentration",
"Meat",
"Swine",
"Time Factors"
] | 1998 | Apr | Evaluation of the extent and type of bacterial contamination at different stages of processing of cooked ham.
In an attempt to determine the composition and origin of the spoilage flora of refrigerated vacuum-packed cooked ham, the changes in microbial numbers and types were followed along the processing line. Results ... |
9,633,663 | eng | [
"D000263",
"Q000378",
"D001426",
"Q000378",
"D001431",
"D001433",
"D001435",
"D004926",
"Q000201",
"Q000302",
"Q000821",
"D008163",
"D012475",
"Q000201",
"Q000302",
"Q000821",
"D012680",
"D013997"
] | [
"Adenylate Kinase",
"Bacterial Proteins",
"Bacteriological Techniques",
"Bacteriolysis",
"Bacteriophages",
"Escherichia coli",
"Luminescent Measurements",
"Salmonella",
"Sensitivity and Specificity",
"Time Factors"
] | 1998 | Apr | Specific assays for bacteria using phage mediated release of adenylate kinase.
A sensitive and rapid assay method for the specific detection of bacteria was developed using Escherichia coli and Salmonella newport as the test organisms. Bacteriophages were used to provide specific lysis of the bacteria and then the rele... |
9,633,664 | eng | [
"D000391",
"D000818",
"D000881",
"Q000382",
"D001408",
"Q000302",
"D001431",
"D018397",
"Q000382",
"D008855",
"D009276",
"D012988",
"D013171",
"Q000302"
] | [
"Air Microbiology",
"Animals",
"Anthrax",
"Bacillus anthracis",
"Bacteriological Techniques",
"Equidae",
"Microscopy, Electron, Scanning",
"Namibia",
"Soil Microbiology",
"Spores, Bacterial"
] | 1998 | Apr | Airborne movement of anthrax spores from carcass sites in the Etosha National Park, Namibia.
Tests for airborne movement of anthrax spores downwind from three heavily contaminated carcass sites were carried out under a range of wind conditions. Anthrax spores were detected in just three of 43 cyclone or gelatin filter ... |
9,633,665 | eng | [
"D000818",
"D001426",
"Q000032",
"D002417",
"D015169",
"D004591",
"D019453",
"Q000737",
"Q000254",
"Q000302",
"Q000502",
"D006360",
"Q000032",
"D018869",
"D015151",
"D008460",
"Q000382",
"D013696",
"D013997"
] | [
"Animals",
"Bacterial Proteins",
"Cattle",
"Colony Count, Microbial",
"Electrophoresis, Polyacrylamide Gel",
"Escherichia coli O157",
"Heat-Shock Proteins",
"Heat-Shock Response",
"Immunoblotting",
"Meat",
"Temperature",
"Time Factors"
] | 1998 | Apr | Heat shock and thermotolerance of Escherichia coli O157:H7 in a model beef gravy system and ground beef.
Duplicate beef gravy or ground beef samples inoculated with a suspension of a four-strain cocktail of Escherichia coli O157:H7 were subjected to sublethal heating at 46 degrees C for 15-30 min, and then heated to a ... |
9,633,666 | eng | [
"D000293",
"D000328",
"D017668",
"D001714",
"Q000145",
"Q000175",
"Q000453",
"D003866",
"Q000145",
"Q000175",
"Q000453",
"D005163",
"D005190",
"D005260",
"D006801",
"D007494",
"Q000453",
"D008297",
"D008875",
"D016017",
"D011618",
"Q000145",
"Q000175",
"Q000453",
"D01... | [
"Adolescent",
"Adult",
"Age of Onset",
"Bipolar Disorder",
"Depressive Disorder",
"Factor Analysis, Statistical",
"Family",
"Female",
"Humans",
"Ireland",
"Male",
"Middle Aged",
"Odds Ratio",
"Psychotic Disorders",
"Registries",
"Reproducibility of Results",
"Risk Factors",
"Schizo... | 1998 | Jun | The structure of psychosis: latent class analysis of probands from the Roscommon Family Study.
The nosologic structure of psychotic illness, still influenced as much by historical as empirical perspectives, remains controversial. Latent class analysis was applied to detailed symptomatic and outcome assessments of proba... |
9,633,669 | eng | [
"D000313",
"Q000294",
"Q000502",
"D000328",
"D000368",
"D001794",
"Q000502",
"D004837",
"Q000097",
"Q000502",
"D005260",
"D006321",
"Q000294",
"Q000503",
"D006339",
"Q000502",
"D006801",
"D008297",
"D008875",
"D009132",
"Q000737",
"Q000294",
"D009206",
"Q000737",
"D00... | [
"Adrenal Medulla",
"Adult",
"Aged",
"Blood Pressure",
"Epinephrine",
"Female",
"Heart",
"Heart Rate",
"Humans",
"Male",
"Middle Aged",
"Muscles",
"Myocardium",
"Norepinephrine",
"Panic Disorder",
"Personality Inventory",
"Radioisotope Dilution Technique",
"Stress, Psychological",
... | 1998 | Jun | Sympathetic activity in patients with panic disorder at rest, under laboratory mental stress, and during panic attacks.
The sympathetic nervous system has long been believed to be involved in the pathogenesis of panic disorder, but studies to date, most using peripheral venous catecholamine measurements, have yielded c... |
9,633,671 | eng | [
"D000328",
"D000553",
"D000596",
"Q000008",
"D002395",
"Q000097",
"Q000502",
"D018592",
"D004311",
"D005260",
"D006719",
"Q000097",
"D006801",
"D008297",
"D008734",
"Q000097",
"D008875",
"D009638",
"Q000097",
"Q000502",
"D010789",
"D010919",
"D016574",
"Q000097",
"Q00... | [
"Adult",
"Ambulatory Care",
"Amino Acids",
"Catecholamines",
"Cross-Over Studies",
"Double-Blind Method",
"Female",
"Homovanillic Acid",
"Humans",
"Male",
"Methoxyhydroxyphenylglycol",
"Middle Aged",
"Norepinephrine",
"Phototherapy",
"Placebos",
"Seasonal Affective Disorder",
"Seroto... | 1998 | Jun | Effects of tryptophan depletion vs catecholamine depletion in patients with seasonal affective disorder in remission with light therapy.
Although hypotheses about the therapeutic mechanism of action of light therapy have focused on serotonergic mechanisms, the potential role, if any, of catecholaminergic pathways has n... |
9,633,672 | eng | [
"D000596",
"Q000008",
"D003866",
"Q000097",
"Q000188",
"Q000503",
"D004569",
"D005526",
"D006801",
"D008297",
"D012701",
"Q000502",
"D017367",
"Q000627",
"D012890",
"Q000502",
"D014364",
"Q000097"
] | [
"Amino Acids",
"Depressive Disorder",
"Electroencephalography",
"Food, Formulated",
"Humans",
"Male",
"Serotonin",
"Selective Serotonin Reuptake Inhibitors",
"Sleep",
"Tryptophan"
] | 1998 | Jun | Rapid tryptophan depletion, sleep electroencephalogram, and mood in men with remitted depression on serotonin reuptake inhibitors.
In previous studies, depletion of brain serotonin by administration of a tryptophan-free amino acid drink (TFD) (1) temporarily reversed the antidepressant effects of selective serotonin re... |
9,633,673 | eng | [
"D000293",
"D000328",
"D001921",
"Q000033",
"D002552",
"Q000033",
"D002555",
"Q000502",
"D005260",
"D006801",
"D008279",
"D008297",
"D008875",
"D011618",
"Q000175",
"D012559",
"Q000175"
] | [
"Adolescent",
"Adult",
"Brain",
"Cerebral Ventricles",
"Cerebrospinal Fluid",
"Female",
"Humans",
"Magnetic Resonance Imaging",
"Male",
"Middle Aged",
"Psychotic Disorders",
"Schizophrenia"
] | 1998 | Jun | Cerebral gray matter volume deficits in first episode psychosis.
Structural brain differences including decreased gray matter and increased cerebrospinal fluid volumes have been observed in the brains of chronically ill patients with schizophrenia. We hypothesized that deficits in gray matter volume would be present in... |
9,633,674 | eng | [
"D019260",
"D005192",
"D006801",
"D012008",
"D015203",
"D012559",
"Q000175",
"Q000453",
"D012565"
] | [
"Expressed Emotion",
"Family Health",
"Humans",
"Recurrence",
"Reproducibility of Results",
"Schizophrenia",
"Schizophrenic Psychology"
] | 1998 | Jun | Expressed emotion and psychiatric relapse: a meta-analysis.
Expressed emotion (EE) is a measure of the family environment that has been demonstrated to be a reliable psychosocial predictor of relapse in schizophrenia. However, in recent years some prominent nonreplications of the EE-relapse relationship have been publi... |
9,633,675 | eng | [
"D000328",
"D000704",
"D001143",
"Q000502",
"D001794",
"Q000502",
"D004636",
"Q000706",
"D005260",
"D006339",
"Q000502",
"D006801",
"D007557",
"Q000453",
"D008016",
"D016014",
"D008297",
"D011336",
"D011569",
"Q000706",
"D013313",
"Q000175",
"Q000453",
"D017741",
"Q00... | [
"Adult",
"Analysis of Variance",
"Arousal",
"Blood Pressure",
"Emergency Service, Hospital",
"Female",
"Heart Rate",
"Humans",
"Israel",
"Life Change Events",
"Linear Models",
"Male",
"Probability",
"Psychiatric Status Rating Scales",
"Stress Disorders, Post-Traumatic",
"Survivors",
... | 1998 | Jun | A prospective study of heart rate response following trauma and the subsequent development of posttraumatic stress disorder.
Physiological arousal during traumatic events may trigger the neurobiological processes that lead to posttraumatic stress disorder (PTSD). This study prospectively examined the relationship betwe... |
9,633,679 | eng | [
"D000978",
"Q000266",
"Q000627",
"D018491",
"Q000266",
"Q000627",
"D004359",
"D049672",
"D049673",
"D006801",
"D007980",
"Q000266",
"Q000627",
"D010300",
"Q000188",
"Q000266"
] | [
"Antiparkinson Agents",
"Dopamine Agonists",
"Drug Therapy, Combination",
"History, 19th Century",
"History, 20th Century",
"Humans",
"Levodopa",
"Parkinson Disease"
] | 1998 | Jun | History of levodopa and dopamine agonists in Parkinson's disease treatment.
Striatal dopamine deficiency in Parkinson's disease (PD), first described in 1960, was a key event that led to the era of levodopa therapy. In 1961, levodopa was first tried in PD patients, but throughout most of the 1960s the results were inco... |
9,633,681 | eng | [
"D000203",
"Q000145",
"D000368",
"D000978",
"Q000009",
"Q000627",
"D002230",
"Q000009",
"Q000627",
"D003692",
"D004305",
"D004338",
"D004409",
"Q000209",
"D005260",
"D006801",
"D007980",
"Q000009",
"Q000627",
"D008297",
"D008875",
"D009460",
"Q000187",
"D010300",
"Q00... | [
"Activities of Daily Living",
"Aged",
"Antiparkinson Agents",
"Carbidopa",
"Delayed-Action Preparations",
"Dose-Response Relationship, Drug",
"Drug Combinations",
"Dyskinesia, Drug-Induced",
"Female",
"Humans",
"Levodopa",
"Male",
"Middle Aged",
"Neurologic Examination",
"Parkinson Disea... | 1998 | Jun | Implications of the 5-year CR FIRST trial. Sinemet CR Five-Year International Response Fluctuation Study.
Almost since the introduction of levodopa for Parkinson's disease (PD), its side effects have concerned clinicians. One strategy to avoid side effects has been to delay levodopa therapy; an alternative has been to ... |
9,633,680 | eng | [
"D000978",
"Q000009",
"Q000493",
"Q000627",
"D003342",
"Q000187",
"Q000503",
"D004298",
"Q000378",
"D015259",
"Q000009",
"Q000493",
"Q000627",
"D006801",
"D009434",
"Q000187",
"Q000503",
"D010300",
"Q000188",
"Q000503",
"D011954",
"Q000187",
"Q000502",
"D013378",
"Q00... | [
"Antiparkinson Agents",
"Corpus Striatum",
"Dopamine",
"Dopamine Agents",
"Humans",
"Neural Pathways",
"Parkinson Disease",
"Receptors, Dopamine",
"Substantia Nigra"
] | 1998 | Jun | Mechanism of action of dopaminergic agents in Parkinson's disease.
As the substantia nigra degenerates in Parkinson's disease (PD), the nigrostriatal pathway is disrupted, reducing striatal dopamine and producing PD symptoms. Although dopamine does not readily cross the blood-brain barrier, its precursor, levodopa, doe... |
9,633,682 | eng | [
"D000203",
"Q000145",
"D000328",
"D000368",
"D000547",
"Q000008",
"Q000009",
"D000978",
"Q000008",
"Q000009",
"D002230",
"Q000008",
"Q000009",
"D018680",
"Q000008",
"Q000009",
"D003692",
"D018491",
"Q000008",
"Q000009",
"D004338",
"D004359",
"D005260",
"D006801",
"D00... | [
"Activities of Daily Living",
"Adult",
"Aged",
"Amantadine",
"Antiparkinson Agents",
"Carbidopa",
"Cholinergic Antagonists",
"Delayed-Action Preparations",
"Dopamine Agonists",
"Drug Combinations",
"Drug Therapy, Combination",
"Female",
"Humans",
"Levodopa",
"Male",
"Middle Aged",
"N... | 1998 | Jun | Initiating therapy for Parkinson's disease.
Accurate diagnosis and individualized assessment of the risks and benefits of available antiparkinsonian medications should guide initiation of treatment for patients with early Parkinson's disease (PD). In general, the goals of treatment for younger patients (less than age 6... |
9,633,683 | eng | [
"D000978",
"Q000008",
"Q000009",
"D018491",
"Q000008",
"Q000009",
"D004305",
"D004334",
"D004359",
"D006801",
"D007980",
"Q000008",
"Q000009",
"D009460",
"Q000187",
"D010300",
"Q000175",
"Q000188",
"D016896"
] | [
"Antiparkinson Agents",
"Dopamine Agonists",
"Dose-Response Relationship, Drug",
"Drug Administration Schedule",
"Drug Therapy, Combination",
"Humans",
"Levodopa",
"Neurologic Examination",
"Parkinson Disease",
"Treatment Outcome"
] | 1998 | Jun | Adjuncts to levodopa therapy: dopamine agonists.
The classical role of dopamine agonists in Parkinson's disease (PD) therapy is adjunctive treatment to levodopa once "wearing-off" fluctuations or more malignant types of "on-off" swings have developed. Dopamine agonists reduce the frequency, severity, and duration of "o... |
9,633,684 | eng | [
"D000978",
"Q000008",
"Q000009",
"D001577",
"Q000008",
"Q000009",
"D002394",
"Q000502",
"D065098",
"D002396",
"Q000008",
"Q000009",
"D004305",
"D004347",
"D004359",
"D004791",
"Q000008",
"Q000009",
"D006801",
"D007980",
"Q000008",
"Q000009",
"Q000493",
"D009570",
"D00... | [
"Antiparkinson Agents",
"Benzophenones",
"Catechol O-Methyltransferase",
"Catechol O-Methyltransferase Inhibitors",
"Catechols",
"Dose-Response Relationship, Drug",
"Drug Interactions",
"Drug Therapy, Combination",
"Enzyme Inhibitors",
"Humans",
"Levodopa",
"Nitriles",
"Nitrophenols",
"Par... | 1998 | Jun | Extending levodopa action: COMT inhibition.
Degradation of levodopa in the periphery is known to be associated with motor fluctuations and dyskinesia in Parkinson's disease (PD) patients. The enzyme catechol-O-methyltransferase (COMT) is responsible for much of this degradation. Therefore, inhibiting COMT activity is o... |
9,633,685 | eng | [
"D000978",
"Q000008",
"Q000009",
"D003704",
"Q000175",
"Q000188",
"D003937",
"D004359",
"D006801",
"D009483",
"D010300",
"Q000175",
"Q000188",
"D011379",
"D011619",
"Q000008",
"Q000009"
] | [
"Antiparkinson Agents",
"Dementia",
"Diagnosis, Differential",
"Drug Therapy, Combination",
"Humans",
"Neuropsychological Tests",
"Parkinson Disease",
"Prognosis",
"Psychotropic Drugs"
] | 1998 | Jun | Managing the neuropsychiatric symptoms of Parkinson's disease.
Neuropsychiatric symptoms frequently complicate the treatment of Parkinson's disease (PD). Approximately 27% of PD patients are demented, and approximately 19% are cognitively impaired without being demented. These 46% of patients are prone to development o... |
9,633,686 | eng | [
"D000818",
"D000978",
"Q000493",
"Q000633",
"D017209",
"Q000187",
"D002470",
"Q000187",
"D004298",
"Q000378",
"D006801",
"D007980",
"Q000493",
"Q000633",
"D009410",
"Q000139",
"D009474",
"Q000187",
"D010300",
"Q000188",
"Q000209",
"D051381",
"D017382",
"Q000378",
"D01... | [
"Animals",
"Antiparkinson Agents",
"Apoptosis",
"Cell Survival",
"Dopamine",
"Humans",
"Levodopa",
"Nerve Degeneration",
"Neurons",
"Parkinson Disease",
"Rats",
"Reactive Oxygen Species",
"Substantia Nigra"
] | 1998 | Jun | Levodopa neurotoxicity: experimental studies versus clinical relevance.
Levodopa therapy remains the major form of treatment for the symptoms of Parkinson's disease (PD). However, there has been a suspicion that its use may hasten the progression of nigral cell degeneration. This concept is based on the ability of levo... |
9,633,690 | eng | [
"D001327",
"Q000382",
"D002648",
"D006801",
"D001523",
"Q000382",
"D009422",
"Q000382",
"D009771",
"Q000382",
"D013290",
"Q000150",
"D005879",
"Q000382"
] | [
"Autoimmune Diseases",
"Child",
"Humans",
"Mental Disorders",
"Nervous System Diseases",
"Obsessive-Compulsive Disorder",
"Streptococcal Infections",
"Tourette Syndrome"
] | 1998 | Jun | Tourette's syndrome and 'PANDAS': will the relation bear out? Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection.
Despite strong evidence of the importance of hereditary factors in the etiology of Tourette's syndrome (TS), research findings have consistently pointed to a role of env... |
9,633,691 | eng | [
"D001519",
"Q000502",
"D001927",
"Q000175",
"Q000503",
"Q000523",
"D002540",
"Q000502",
"D006801",
"D008279",
"D012016"
] | [
"Behavior",
"Brain Diseases",
"Cerebral Cortex",
"Humans",
"Magnetic Resonance Imaging",
"Reference Values"
] | 1998 | Jun | The behavioral neurology of cerebral white matter.
Behavioral neurology has primarily focused on brain-behavior relations as revealed by disorders of the cerebral cortex and subcortical gray matter. Disorders of cerebral white matter have received less attention. This article considers the contribution of cerebral whit... |
9,633,692 | eng | [
"D000328",
"D017668",
"D000368",
"D000369",
"D001057",
"Q000235",
"D002886",
"Q000235",
"D003704",
"Q000453",
"Q000235",
"Q000503",
"D005260",
"D005625",
"Q000503",
"D005838",
"D006801",
"D008297",
"D008875",
"D016016",
"D013702",
"Q000503"
] | [
"Adult",
"Age of Onset",
"Aged",
"Aged, 80 and over",
"Apolipoproteins E",
"Chromosomes, Human, Pair 17",
"Dementia",
"Female",
"Frontal Lobe",
"Genotype",
"Humans",
"Male",
"Middle Aged",
"Proportional Hazards Models",
"Temporal Lobe"
] | 1998 | Jun | Familial aggregation in frontotemporal dementia.
Frontotemporal dementia (FTD) is a common, non-Alzheimer's dementia. Its familial occurrence has been reported, but the frequency of positive family history is unknown. We carried out a nationwide genetic-epidemiologic study of FTD in the Dutch population of 15 million p... |
9,633,693 | eng | [
"D000328",
"D000368",
"D000369",
"D000544",
"Q000235",
"D002102",
"D002874",
"D002886",
"Q000235",
"D002893",
"Q000235",
"D003704",
"Q000175",
"Q000235",
"D005625",
"Q000473",
"Q000503",
"D008040",
"Q000235",
"D006239",
"D006801",
"D008297",
"D008875",
"D010375",
"D01... | [
"Adult",
"Aged",
"Aged, 80 and over",
"Alzheimer Disease",
"Cadaver",
"Chromosome Mapping",
"Chromosomes, Human, Pair 17",
"Chromosomes, Human, Pair 3",
"Dementia",
"Frontal Lobe",
"Genetic Linkage",
"Haplotypes",
"Humans",
"Male",
"Middle Aged",
"Pedigree",
"Prions",
"Temporal Lob... | 1998 | Jun | Hereditary dysphasic disinhibition dementia: a frontotemporal dementia linked to 17q21-22.
The clinical and pathologic features of hereditary dysphasic disinhibition dementia (HDDD) are described to determine whether it is a variant of known dementias. Several dementing disorders have clinical and pathologic similariti... |
9,633,694 | eng | [
"D000368",
"D000483",
"D000544",
"Q000235",
"D019389",
"Q000235",
"D005838",
"D006801",
"D018895",
"Q000235",
"D009154",
"Q000235",
"D010300",
"Q000235",
"D011110",
"Q000235"
] | [
"Aged",
"Alleles",
"Alzheimer Disease",
"Cytochrome P-450 CYP2D6",
"Genotype",
"Humans",
"Microsatellite Repeats",
"Mutation",
"Parkinson Disease",
"Polymorphism, Genetic"
] | 1998 | Jun | Association of CYP2D microsatellite polymorphism with Lewy body variant of Alzheimer's disease.
To examine the genetic association of CYP2D6 locus with Lewy body variant (LBV) and Parkinson's disease (PD). Allelic association was studied in patients with pure AD, LBV, and PD by using the CYP2D microsatellite, the (dG-d... |
9,633,695 | eng | [
"D000368",
"D000544",
"Q000175",
"Q000503",
"Q000523",
"D001921",
"Q000000981",
"Q000473",
"D002560",
"Q000502",
"D016002",
"D018450",
"D005260",
"D005544",
"D006801",
"D008279",
"D008297",
"D009483",
"D015899"
] | [
"Aged",
"Alzheimer Disease",
"Brain",
"Cerebrovascular Circulation",
"Discriminant Analysis",
"Disease Progression",
"Female",
"Forecasting",
"Humans",
"Magnetic Resonance Imaging",
"Male",
"Neuropsychological Tests",
"Tomography, Emission-Computed, Single-Photon"
] | 1998 | Jun | Preclinical prediction of Alzheimer's disease using SPECT.
Regional cerebral perfusion measured by single photon emission computed tomography (SPECT) was examined as a preclinical predictor of the development of Alzheimer's disease (AD). Singular value decomposition was used to produce 20 SPECT factors (known as vector... |
9,633,696 | eng | [
"D017677",
"D000368",
"D000369",
"D000544",
"Q000453",
"Q000401",
"D015140",
"Q000453",
"Q000401",
"D005260",
"D006801",
"D015994",
"D008297",
"D017678",
"D012959",
"D013624"
] | [
"Age Distribution",
"Aged",
"Aged, 80 and over",
"Alzheimer Disease",
"Dementia, Vascular",
"Female",
"Humans",
"Incidence",
"Male",
"Sex Distribution",
"Socioeconomic Factors",
"Taiwan"
] | 1998 | Jun | Incidence and subtypes of dementia in southern Taiwan: impact of socio-demographic factors.
To determine the incidence rate (IR) and subtypes of dementia in southern Taiwan. From a cohort of 2,915 community inhabitants aged 65 years and over, 2,507 and 2,175 subjects participated in the first- and second-year follow-up... |
9,633,698 | eng | [
"D000368",
"D000544",
"Q000175",
"Q000000981",
"Q000378",
"D001284",
"D001921",
"Q000000981",
"Q000378",
"D005260",
"D005947",
"Q000378",
"D006801",
"D007091",
"D008279",
"D008297",
"D008875",
"D012016",
"D014018",
"D014055"
] | [
"Aged",
"Alzheimer Disease",
"Atrophy",
"Brain",
"Female",
"Glucose",
"Humans",
"Image Processing, Computer-Assisted",
"Magnetic Resonance Imaging",
"Male",
"Middle Aged",
"Reference Values",
"Tissue Distribution",
"Tomography, Emission-Computed"
] | 1998 | Jun | Regional glucose metabolic abnormalities are not the result of atrophy in Alzheimer's disease.
To determine whether the hypometabolism observed in PET images of patients with Alzheimer's disease (AD) is due entirely to brain atrophy. Reduced brain glucose metabolism in AD patients measured using PET has been reported b... |
9,633,697 | eng | [
"D000368",
"D000375",
"Q000502",
"D053327",
"D001057",
"Q000097",
"Q000235",
"D002318",
"Q000209",
"D003072",
"Q000150",
"Q000235",
"Q000523",
"D005838",
"D006579",
"D006801",
"D006943",
"Q000150",
"D006973",
"Q000150",
"D008137",
"D008297",
"D009483",
"D011446",
"D01... | [
"Aged",
"Aging",
"Apolipoprotein E4",
"Apolipoproteins E",
"Cardiovascular Diseases",
"Cognition Disorders",
"Genotype",
"Heterozygote",
"Humans",
"Hyperglycemia",
"Hypertension",
"Longitudinal Studies",
"Male",
"Neuropsychological Tests",
"Prospective Studies",
"Risk Factors",
"Vete... | 1998 | Jun | Midlife cardiovascular risk factors, ApoE, and cognitive decline in elderly male twins.
To investigate the combined effect of the apolipoprotein E epsilon4 (ApoE*4) allele and midlife cardiovascular risk factors on cognitive decline. Data are from the National Heart, Lung, and Blood Institute Twin Study-a longitudinal ... |
9,633,699 | eng | [
"D015331",
"D004185",
"D005260",
"D017048",
"D006296",
"Q000706",
"D006801",
"D007297",
"D008297",
"D008875",
"D008910",
"D009103",
"Q000503",
"Q000628",
"D010045"
] | [
"Cohort Studies",
"Disability Evaluation",
"Female",
"Health Care Costs",
"Health Services",
"Humans",
"Inpatients",
"Male",
"Middle Aged",
"Minnesota",
"Multiple Sclerosis",
"Outpatients"
] | 1998 | Jun | Health care utilization in multiple sclerosis: a population-based study in Olmsted County, MN.
The authors sought to determine acute ambulatory- and hospital-billed charges for the Olmsted County, Minnesota Multiple Sclerosis (MS) Disability Prevalence Cohort and compare them to those incurred by the general population... |
9,633,700 | eng | [
"D000328",
"D001921",
"Q000473",
"Q000503",
"D003072",
"Q000175",
"Q000523",
"D005260",
"D005625",
"Q000473",
"Q000503",
"D006801",
"D008279",
"Q000379",
"D008297",
"D008875",
"D009103",
"Q000175",
"Q000503",
"Q000523",
"D009483"
] | [
"Adult",
"Brain",
"Cognition Disorders",
"Female",
"Frontal Lobe",
"Humans",
"Magnetic Resonance Imaging",
"Male",
"Middle Aged",
"Multiple Sclerosis",
"Neuropsychological Tests"
] | 1998 | Jun | Relation between MR abnormalities and patterns of cognitive impairment in multiple sclerosis.
This study correlated the extent of abnormalities detected by different magnetic resonance imaging (MRI) techniques [proton density (PD)-weighted, T1-weighted, and magnetization transfer imaging (MTI)] with the overall cogniti... |
9,633,701 | eng | [
"D000328",
"D001921",
"Q000473",
"D004185",
"D005260",
"D006801",
"D008279",
"D008297",
"D008875",
"D009103",
"Q000175",
"Q000503",
"Q000523",
"D009420",
"Q000503",
"D009483",
"D012016"
] | [
"Adult",
"Brain",
"Disability Evaluation",
"Female",
"Humans",
"Magnetic Resonance Imaging",
"Male",
"Middle Aged",
"Multiple Sclerosis",
"Nervous System",
"Neuropsychological Tests",
"Reference Values"
] | 1998 | Jun | Correlation of volumetric magnetization transfer imaging with clinical data in MS.
We examined the relations between quantitative volumetric estimates of cerebral lesion load based on magnetization transfer imaging (MTI), clinical data, and measures of neuropsychological function in 44 patients with clinically diagnose... |
9,633,702 | eng | [
"D000293",
"D000906",
"Q000032",
"D000907",
"Q000032",
"D015153",
"D002648",
"D004797",
"D005260",
"D006801",
"D008297",
"D009474",
"Q000276",
"D011699",
"Q000276",
"Q000473",
"D013291",
"Q000276",
"D005879",
"Q000276",
"Q000503"
] | [
"Adolescent",
"Antibodies",
"Antibodies, Bacterial",
"Blotting, Western",
"Child",
"Enzyme-Linked Immunosorbent Assay",
"Female",
"Humans",
"Male",
"Neurons",
"Putamen",
"Streptococcus",
"Tourette Syndrome"
] | 1998 | Jun | Antibodies against human putamen in children with Tourette syndrome.
Similar to the model for Sydenham's chorea, antineuronal antibodies, which develop in response to a preceding streptococcal infection, have been speculated to have a role in the development of Tourette syndrome (TS). Serum antibodies against human cau... |
9,633,703 | eng | [
"D000328",
"D000368",
"D000369",
"D000818",
"D000906",
"Q000032",
"D001681",
"Q000592",
"D015153",
"Q000592",
"D001905",
"Q000008",
"Q000276",
"Q000627",
"D004421",
"Q000188",
"Q000276",
"D005138",
"D005152",
"D005260",
"D006801",
"D007267",
"D008297",
"D051379",
"D00... | [
"Adult",
"Aged",
"Aged, 80 and over",
"Animals",
"Antibodies",
"Biological Assay",
"Blotting, Western",
"Botulinum Toxins",
"Dystonia",
"Eyebrows",
"Facial Muscles",
"Female",
"Humans",
"Injections",
"Male",
"Mice",
"Middle Aged",
"Neck Muscles",
"Sensitivity and Specificity",
... | 1998 | Jun | Mouse bioassay versus Western blot assay for botulinum toxin antibodies: correlation with clinical response.
To compare the mouse protection bioassay (MPB) to the Western blot assay (WBA) in detecting antibodies against botulinum toxin A (BTX-A) and to correlate the assay results with clinical responses to BTX-A inject... |
9,633,704 | eng | [
"D000203",
"D000328",
"D000368",
"D004311",
"D005260",
"D005677",
"Q000627",
"D006801",
"D007262",
"D008297",
"D008875",
"D009068",
"Q000502",
"D010300",
"Q000188",
"Q000503",
"D010919",
"D011446",
"D011597",
"Q000502",
"D012720",
"D016138",
"Q000502"
] | [
"Activities of Daily Living",
"Adult",
"Aged",
"Double-Blind Method",
"Female",
"G(M1) Ganglioside",
"Humans",
"Infusions, Intravenous",
"Male",
"Middle Aged",
"Movement",
"Parkinson Disease",
"Placebos",
"Prospective Studies",
"Psychomotor Performance",
"Severity of Illness Index",
... | 1998 | Jun | Parkinson's disease: improved function with GM1 ganglioside treatment in a randomized placebo-controlled study.
Studies in animal models of Parkinson's disease (PD) suggest that GM1 ganglioside treatment can restore neurologic and dopaminergic function. In view of positive preclinical findings and the results of a prev... |
9,633,705 | eng | [
"D000342",
"Q000209",
"D000368",
"D000369",
"D003072",
"Q000209",
"D003951",
"D018450",
"D005260",
"D006306",
"D006801",
"D008297",
"D008875",
"D009026",
"D009069",
"Q000209",
"D017678",
"D012893",
"Q000209",
"D013494",
"Q000175",
"Q000503",
"Q000523",
"D011795",
"D01... | [
"Affective Symptoms",
"Aged",
"Aged, 80 and over",
"Cognition Disorders",
"Diagnostic Errors",
"Disease Progression",
"Female",
"Health Surveys",
"Humans",
"Male",
"Middle Aged",
"Mortality",
"Movement Disorders",
"Sex Distribution",
"Sleep Wake Disorders",
"Supranuclear Palsy, Progres... | 1998 | Jun | Progressive supranuclear palsy: a survey of the disease course.
The most accurate knowledge about progressive supranuclear palsy (PSP) comes from small sample studies that preclude precise estimation of the proportion of PSP patients affected with various symptoms and the examination of factors predicting survival time... |
9,633,706 | eng | [
"D000368",
"D007839",
"D006225",
"Q000503",
"D006801",
"D008875",
"D010300",
"Q000503",
"D011597",
"Q000502",
"D011698",
"Q000502",
"D012016"
] | [
"Aged",
"Functional Laterality",
"Hand",
"Humans",
"Middle Aged",
"Parkinson Disease",
"Psychomotor Performance",
"Pursuit, Smooth",
"Reference Values"
] | 1998 | Jun | Visuomotor control abnormalities in patients with unilateral parkinsonism.
Visuomotor performance is known to be disturbed in patients who have advanced Parkinson's disease (PD). The degree of impairment in the early stages of PD was investigated in both the symptomatic and asymptomatic hand of patients with unilateral... |
9,633,707 | eng | [
"D000328",
"D004558",
"D005073",
"Q000502",
"D005260",
"D006801",
"D015640",
"Q000502",
"D008297",
"D009119",
"Q000502",
"D018482",
"Q000502",
"D013003",
"Q000502",
"D013979",
"Q000502"
] | [
"Adult",
"Electric Stimulation",
"Evoked Potentials, Somatosensory",
"Female",
"Humans",
"Ion Channel Gating",
"Male",
"Muscle Contraction",
"Muscle, Skeletal",
"Somatosensory Cortex",
"Tibial Nerve"
] | 1998 | Jun | Effects of voluntary contraction on tibial nerve somatosensory evoked potentials: gating of specific cortical responses.
We evaluated vertex-parietal P37, N50, and contralateral N37 somatosensory evoked potentials (SEPs) to posterior tibial nerve stimulation during weak (20 to 30%) and strong (80 to 90%) ipsilateral ga... |
9,633,708 | eng | [
"D001291",
"D003955",
"Q000706",
"D007600",
"D015999",
"D009422",
"Q000175",
"Q000628",
"D009462",
"Q000379",
"D010818",
"D006113",
"D014481"
] | [
"Attitude of Health Personnel",
"Diagnostic Tests, Routine",
"Judgment",
"Multivariate Analysis",
"Nervous System Diseases",
"Neurology",
"Practice Patterns, Physicians'",
"United Kingdom",
"United States"
] | 1998 | Jun | Practice styles of US compared to UK neurologists.
This study assessed variation between neurologists in the United States and United Kingdom in their diagnostic and treatment decisions for commonly encountered neurologic presentations, and identified explanatory factors for any observed variation. All 210 consultant n... |
9,633,709 | eng | [
"D000328",
"D000368",
"D000369",
"D001281",
"Q000150",
"D002545",
"Q000150",
"Q000628",
"D002561",
"Q000150",
"Q000628",
"D005194",
"Q000379",
"D005260",
"D006333",
"Q000150",
"D006801",
"D007297",
"D008297",
"D008875",
"D009462",
"Q000379",
"D010818",
"D016016",
"D01... | [
"Adult",
"Aged",
"Aged, 80 and over",
"Atrial Fibrillation",
"Brain Ischemia",
"Cerebrovascular Disorders",
"Family Practice",
"Female",
"Heart Failure",
"Humans",
"Inpatients",
"Male",
"Middle Aged",
"Neurology",
"Practice Patterns, Physicians'",
"Proportional Hazards Models",
"Recu... | 1998 | Jun | Ischemic stroke: outcomes, patient mix, and practice variation for neurologists and generalists in a community.
A variety of methods was used to compare patient mix, practice variation, survival, and recurrence after first ischemic stroke among Rochester, MN residents. The significance of the results for neurologists a... |
9,633,710 | eng | [
"D000293",
"D000328",
"D000755",
"Q000150",
"D001288",
"Q000502",
"D002544",
"Q000175",
"Q000209",
"Q000523",
"D002648",
"D003071",
"Q000502",
"D006801",
"D009483",
"D012680"
] | [
"Adolescent",
"Adult",
"Anemia, Sickle Cell",
"Attention",
"Cerebral Infarction",
"Child",
"Cognition",
"Humans",
"Neuropsychological Tests",
"Sensitivity and Specificity"
] | 1998 | Jun | Cognitive screening examinations for silent cerebral infarcts in sickle cell disease.
In children with sickle cell disease (SCD), silent cerebral infarcts are the most frequent cause of neurologic injury. We determined the sensitivity and specificity of selective neurocognitive measures when separating children with si... |
9,633,711 | eng | [
"D000368",
"D000925",
"Q000627",
"D001458",
"D002561",
"Q000150",
"Q000628",
"D005260",
"D005676",
"D006493",
"Q000627",
"D006801",
"D008297",
"D011446",
"D011655",
"Q000453",
"Q000401",
"D012307",
"D013923",
"Q000453",
"Q000209",
"D013924",
"Q000453",
"Q000517"
] | [
"Aged",
"Anticoagulants",
"Bandages",
"Cerebrovascular Disorders",
"Female",
"Gravity Suits",
"Heparin",
"Humans",
"Male",
"Prospective Studies",
"Pulmonary Embolism",
"Risk Factors",
"Thromboembolism",
"Thrombophlebitis"
] | 1998 | Jun | Pneumatic sequential compression reduces the risk of deep vein thrombosis in stroke patients.
To determine if pneumatic sequential compression devices (SCDs) combined with subcutaneous heparin and antiembolic hose reduce the risk of deep vein thrombosis (DVT) and pulmonary embolism (PE) in stroke patients. DVTs and PEs... |
9,633,712 | eng | [
"D000293",
"D000328",
"D001741",
"Q000706",
"D002545",
"Q000139",
"Q000453",
"Q000209",
"D002561",
"Q000139",
"Q000453",
"Q000209",
"D005260",
"D006801",
"D013287",
"Q000009",
"D015994",
"D008297",
"D012307",
"D019966",
"Q000208",
"D014505",
"D044465",
"Q000706"
] | [
"Adolescent",
"Adult",
"Black or African American",
"Brain Ischemia",
"Cerebrovascular Disorders",
"Female",
"Humans",
"Illicit Drugs",
"Incidence",
"Male",
"Risk Factors",
"Substance-Related Disorders",
"Urban Population",
"White People"
] | 1998 | Jun | Illicit drug-associated ischemic stroke in the Baltimore-Washington Young Stroke Study.
Limited information exists on the frequency, trends in occurrence, risk factors, mechanisms, and outcome of ischemic stroke associated with illicit drug use among young adults in a geographically defined population. We reviewed isch... |
9,633,713 | eng | [
"D000368",
"D000369",
"D001488",
"Q000000981",
"Q000473",
"D002545",
"Q000150",
"Q000175",
"D002343",
"Q000000981",
"Q000473",
"D002533",
"D002539",
"Q000150",
"Q000175",
"D002561",
"Q000150",
"Q000175",
"D005260",
"D006801",
"D008279",
"D008297",
"D008875",
"D012008",
... | [
"Aged",
"Aged, 80 and over",
"Basilar Artery",
"Brain Ischemia",
"Carotid Artery, Internal",
"Cerebral Angiography",
"Cerebral Arterial Diseases",
"Cerebrovascular Disorders",
"Female",
"Humans",
"Magnetic Resonance Imaging",
"Male",
"Middle Aged",
"Recurrence",
"Survival Analysis",
"T... | 1998 | Jun | Dolichoectasia of the intracranial arteries in patients with first ischemic stroke: a population-based study.
The objective of this study was to estimate the frequency of intracranial arterial dolichoectasia among patients with first ischemic stroke and to compare clinical characteristics, survival, and recurrence in t... |
9,633,714 | eng | [
"D000716",
"D002536",
"Q000033",
"D006801",
"D008488"
] | [
"Anatomy, Artistic",
"Cerebral Arteries",
"Humans",
"Medical Illustration"
] | 1998 | Jun | Arterial territories of the human brain: cerebral hemispheres.
The development of neuroimaging has allowed clinicians to improve clinicoanatomic correlations in patients with stroke. Anatomic structures are well delineated on MRI, but there is a lack of standardization in their arterial supply. As in our previous study... |
9,633,715 | eng | [
"D000293",
"D000328",
"D000368",
"D000369",
"D002543",
"Q000209",
"D002550",
"Q000002",
"Q000000981",
"Q000473",
"D002648",
"D002675",
"D005260",
"D006261",
"Q000209",
"D006801",
"D008137",
"D008279",
"D008297",
"D008875",
"D009422",
"Q000209",
"D011446",
"D012189",
"... | [
"Adolescent",
"Adult",
"Aged",
"Aged, 80 and over",
"Cerebral Hemorrhage",
"Cerebral Veins",
"Child",
"Child, Preschool",
"Female",
"Headache",
"Humans",
"Longitudinal Studies",
"Magnetic Resonance Imaging",
"Male",
"Middle Aged",
"Nervous System Diseases",
"Prospective Studies",
"... | 1998 | Jun | A longitudinal study of patients with venous malformations: documentation of a negligible hemorrhage risk and benign natural history.
The natural history of cerebral venous malformations has not been well documented, and the clinical significance of these common lesions remains controversial. The objective of this stud... |
9,633,716 | eng | [
"D000293",
"D000328",
"D001927",
"Q000175",
"Q000235",
"Q000503",
"D002539",
"Q000175",
"Q000235",
"Q000503",
"D002544",
"Q000175",
"Q000235",
"Q000503",
"D002560",
"Q000502",
"D003704",
"Q000235",
"Q000473",
"Q000523",
"D018450",
"D005260",
"D005799",
"D006801",
"D00... | [
"Adolescent",
"Adult",
"Brain Diseases",
"Cerebral Arterial Diseases",
"Cerebral Infarction",
"Cerebrovascular Circulation",
"Dementia",
"Disease Progression",
"Female",
"Genes, Dominant",
"Humans",
"Magnetic Resonance Imaging",
"Male",
"Middle Aged",
"Migraine Disorders",
"Neuropsycho... | 1998 | Jun | SPECT study of a German CADASIL family: a phenotype with migraine and progressive dementia only.
We describe the clinical, molecular, genetic, MRI, and SPECT features of a German family with autosomal dominant migraine and dementia, mapping to the cerebral autosomal dominant arteriopathy with subcortical infarcts and l... |
9,633,718 | eng | [
"D002012",
"Q000150",
"Q000453",
"D002648",
"D005152",
"Q000503",
"D005260",
"D006261",
"Q000150",
"Q000453",
"Q000628",
"D006801",
"D008297",
"D008881",
"Q000503",
"D009041",
"Q000150",
"Q000453",
"D010146",
"Q000150",
"Q000453",
"D015995",
"D012016",
"D013334",
"D01... | [
"Bruxism",
"Child",
"Facial Muscles",
"Female",
"Headache",
"Humans",
"Male",
"Migraine Disorders",
"Motion Sickness",
"Pain",
"Prevalence",
"Reference Values",
"Students",
"Surveys and Questionnaires",
"Temporomandibular Joint",
"Tension-Type Headache"
] | 1998 | Jun | Childhood headache at school entry: a controlled clinical study.
Our objective was to study the prevalence of different headache types, characterizations, and triggers of headache in Finnish children starting school. Questionnaires were sent to 1,132 families with 6-year-old children. Children with headache disturbing ... |
9,633,717 | eng | [
"D000209",
"Q000378",
"D000210",
"Q000503",
"D000368",
"D002561",
"Q000150",
"Q000378",
"D005260",
"D005340",
"Q000032",
"D006801",
"D007249",
"Q000209",
"D008137",
"D008297",
"D008875",
"D012008",
"D012016",
"D012307"
] | [
"Acute-Phase Proteins",
"Acute-Phase Reaction",
"Aged",
"Cerebrovascular Disorders",
"Female",
"Fibrinogen",
"Humans",
"Inflammation",
"Longitudinal Studies",
"Male",
"Middle Aged",
"Recurrence",
"Reference Values",
"Risk Factors"
] | 1998 | Jun | Persistent inflammatory response in stroke survivors.
Goals were to determine how long acute-phase markers remain elevated after ischemic stroke and how marker levels relate to stroke risk factors, stroke mechanism, and subsequent vascular events. Fibrinogen (FIB), C-reactive protein (CRP), leukocytes (WBC), neutrophil... |
9,633,719 | eng | [
"D000293",
"D000328",
"D000368",
"D000369",
"D001810",
"Q000502",
"D002560",
"Q000502",
"D005260",
"D006801",
"D008297",
"D008875",
"D008881",
"Q000000981",
"Q000503",
"D010101",
"Q000502",
"D014055"
] | [
"Adolescent",
"Adult",
"Aged",
"Aged, 80 and over",
"Blood Volume",
"Cerebrovascular Circulation",
"Female",
"Humans",
"Male",
"Middle Aged",
"Migraine Disorders",
"Oxygen Consumption",
"Tomography, Emission-Computed"
] | 1998 | Jun | Global cerebral blood flow, blood volume, and oxygen metabolism in patients with migraine headache.
Migraine headaches with and without aura are representative of vascular headache states traditionally thought to be mediated by alterations in vascular tone. Validation of this theory has been hampered in part by technic... |
9,633,720 | eng | [
"D000041",
"D000293",
"D000368",
"D005260",
"D006261",
"Q000453",
"Q000503",
"D006801",
"D015994",
"D008297",
"D008499",
"D008875",
"D008881",
"Q000453",
"Q000503",
"D013647",
"D014937"
] | [
"Absenteeism",
"Adolescent",
"Aged",
"Female",
"Headache",
"Humans",
"Incidence",
"Male",
"Medical Records",
"Middle Aged",
"Migraine Disorders",
"Task Performance and Analysis",
"Work"
] | 1998 | Jun | Migraine and reduced work performance: a population-based diary study.
This article estimates lost work days and lost work day equivalents in a population sample of migraineurs, differentiating work loss due to headache episodes that met criteria for migraine from migrainous headaches not meeting full criteria and nonm... |
9,633,721 | eng | [
"D000293",
"D000328",
"D000375",
"Q000502",
"D000704",
"D001921",
"Q000473",
"D002561",
"Q000175",
"Q000209",
"D002648",
"D018450",
"D000795",
"Q000150",
"D006801",
"D008137",
"D008279",
"D008875"
] | [
"Adolescent",
"Adult",
"Aging",
"Analysis of Variance",
"Brain",
"Cerebrovascular Disorders",
"Child",
"Disease Progression",
"Fabry Disease",
"Humans",
"Longitudinal Studies",
"Magnetic Resonance Imaging",
"Middle Aged"
] | 1998 | Jun | Quantitative analysis of cerebral vasculopathy in patients with Fabry disease.
This study's purpose was to obtain a quantitative natural history of the cerebrovascular involvement in Fabry disease. Fabry disease is an X-linked recessive disorder due to alpha-galactosidase A deficiency. Progressive accumulation of ceram... |
9,633,722 | eng | [
"D001483",
"D015139",
"D002549",
"Q000235",
"D005260",
"D005838",
"D006239",
"D006801",
"D008297",
"D005810",
"Q000502",
"D009154",
"Q000235",
"D018991",
"Q000235",
"D010375",
"D010641",
"D016133"
] | [
"Base Sequence",
"Blotting, Southern",
"Diffuse Cerebral Sclerosis of Schilder",
"Female",
"Genotype",
"Haplotypes",
"Humans",
"Male",
"Multigene Family",
"Mutation",
"Myelin Proteolipid Protein",
"Pedigree",
"Phenotype",
"Polymerase Chain Reaction"
] | 1998 | Jun | Duplication of the proteolipid protein gene is the major cause of Pelizaeus-Merzbacher disease.
Pelizaeus-Merzbacher disease (PMD), an X-linked recessive dysmyelination disorder, is caused by mutations in the proteolipid protein (PLP) gene. However, missense mutations were only found in a fraction of PMD patients, even... |
9,633,723 | eng | [
"D000008",
"Q000000981",
"Q000453",
"D000328",
"D015331",
"D006801",
"D015994",
"D008875",
"D009378",
"Q000000981",
"D018317",
"Q000000981",
"Q000453",
"D009456",
"Q000000981",
"Q000453",
"D010386",
"Q000000981",
"Q000453",
"D013902",
"D013899",
"Q000000981",
"Q000453",
... | [
"Abdominal Neoplasms",
"Adult",
"Cohort Studies",
"Humans",
"Incidence",
"Middle Aged",
"Neoplasms, Multiple Primary",
"Nerve Sheath Neoplasms",
"Neurofibromatosis 1",
"Pelvic Neoplasms",
"Radiography, Thoracic",
"Thoracic Neoplasms",
"Tomography, X-Ray Computed"
] | 1998 | Jun | CT imaging in adults with neurofibromatosis-1: frequent asymptomatic plexiform lesions.
The authors examined the incidence and radiologic characteristics of plexiform neurofibromas in neurofibromatosis-1 (NF-1) to define a cohort at greatest risk for malignant nerve-sheath tumors. Plexiform neurofibromas are a frequent... |
9,633,724 | eng | [
"D002675",
"D005260",
"D006801",
"D007223",
"D007231",
"D008297",
"D016472",
"Q000209",
"Q000517",
"Q000601",
"D011446",
"D016136",
"Q000150",
"Q000503",
"Q000601",
"D013116",
"Q000601",
"D013997",
"D016896",
"D001750",
"Q000209",
"Q000517",
"Q000628",
"D014563",
"Q00... | [
"Child, Preschool",
"Female",
"Humans",
"Infant",
"Infant, Newborn",
"Male",
"Motor Neuron Disease",
"Prospective Studies",
"Spina Bifida Occulta",
"Spinal Cord",
"Time Factors",
"Treatment Outcome",
"Urinary Bladder, Neurogenic",
"Urodynamics"
] | 1998 | Jun | Tethered cord syndrome in occult spinal dysraphism: timing and outcome of surgical release.
To investigate the influence of neurosurgical intervention on the appearance of upper motor neuron (UMN) signs in newborns diagnosed with occult spinal dysraphism and tethered cord (TC) during the first month of life. A prospect... |
9,633,725 | eng | [
"D000293",
"D000328",
"D004569",
"D004827",
"Q000503",
"Q000601",
"D005260",
"D005625",
"Q000503",
"Q000601",
"D006801",
"D008297",
"D008875",
"D016896"
] | [
"Adolescent",
"Adult",
"Electroencephalography",
"Epilepsy",
"Female",
"Frontal Lobe",
"Humans",
"Male",
"Middle Aged",
"Treatment Outcome"
] | 1998 | Jun | EEG findings in frontal lobe epilepsies.
As a group, epilepsies of frontal lobe origin are thought to be poorly localized using surface EEG recordings. This finding may depend on the specific areas of frontal lobe from which the seizures originate or the pathologic substrate. We reviewed the presurgical surface EEGs of... |
9,633,727 | eng | [
"D000293",
"D000328",
"D000368",
"D000369",
"D000906",
"Q000032",
"D001379",
"Q000009",
"Q000627",
"D004311",
"D004359",
"D005260",
"D005938",
"Q000008",
"Q000009",
"Q000627",
"D006801",
"D007166",
"Q000009",
"Q000627",
"D008297",
"D008875",
"D009157",
"Q000188",
"D01... | [
"Adolescent",
"Adult",
"Aged",
"Aged, 80 and over",
"Antibodies",
"Azathioprine",
"Double-Blind Method",
"Drug Therapy, Combination",
"Female",
"Glucocorticoids",
"Humans",
"Immunosuppressive Agents",
"Male",
"Middle Aged",
"Myasthenia Gravis",
"Prednisolone",
"Receptors, Cholinergic... | 1998 | Jun | A randomized double-blind trial of prednisolone alone or with azathioprine in myasthenia gravis. Myasthenia Gravis Study Group.
We compared prednisolone (PRED) and azathioprine (AZA) versus prednisolone alone in the treatment of MG. Prednisolone alone or combined with azathioprine is widely used in the treatment of MG,... |
9,633,726 | eng | [
"D000328",
"D002940",
"Q000502",
"D004569",
"D004833",
"Q000175",
"Q000503",
"Q000601",
"D005260",
"D006801",
"D015994",
"D008279",
"D008297",
"D008875",
"D015995",
"D003294",
"Q000453",
"D016896"
] | [
"Adult",
"Circadian Rhythm",
"Electroencephalography",
"Epilepsy, Temporal Lobe",
"Female",
"Humans",
"Incidence",
"Magnetic Resonance Imaging",
"Male",
"Middle Aged",
"Prevalence",
"Seizures, Febrile",
"Treatment Outcome"
] | 1998 | Jun | Nocturnal temporal lobe epilepsy.
To analyze clinical, electrophysiologic, and neuroradiologic characteristics and prognostic factors in a group of patients with temporal lobe epilepsy (TLE) and complex partial seizures (CPS) occurring exclusively or predominantly after they fall asleep or before they awaken. CPS arisi... |
9,633,729 | eng | [
"D000293",
"D000328",
"D017668",
"D002648",
"D002675",
"D002895",
"Q000235",
"D015246",
"Q000235",
"D004827",
"Q000235",
"D005260",
"D017353",
"D005838",
"D006801",
"D008607",
"Q000235",
"D008297",
"D009136",
"Q000453",
"Q000235",
"D010641",
"D012091",
"Q000235"
] | [
"Adolescent",
"Adult",
"Age of Onset",
"Child",
"Child, Preschool",
"Chromosomes, Human, Pair 5",
"Deoxyribonuclease EcoRI",
"Epilepsy",
"Female",
"Gene Deletion",
"Genotype",
"Humans",
"Intellectual Disability",
"Male",
"Muscular Dystrophies",
"Phenotype",
"Repetitive Sequences, Nuc... | 1998 | Jun | Epilepsy and mental retardation in a subset of early onset 4q35-facioscapulohumeral muscular dystrophy.
The gene for facioscapulohumeral muscular dystrophy (FSHD) has been mapped to chromosome 4q35. In most patients with FSHD, a deletion of 3.3 kb tandemly repeated units within the EcoRI fragment that can be detected b... |
9,633,728 | eng | [
"D015139",
"D002675",
"D004247",
"Q000032",
"D004272",
"Q000235",
"Q000378",
"D003576",
"Q000378",
"D006651",
"D006801",
"D007150",
"D007223",
"D008297",
"D018485",
"Q000473",
"D009132",
"Q000201",
"Q000473",
"D010375",
"D016133"
] | [
"Blotting, Southern",
"Child, Preschool",
"DNA",
"DNA, Mitochondrial",
"Electron Transport Complex IV",
"Histocytochemistry",
"Humans",
"Immunohistochemistry",
"Infant",
"Male",
"Muscle Fibers, Skeletal",
"Muscles",
"Pedigree",
"Polymerase Chain Reaction"
] | 1998 | Jun | Clinical manifestations of mitochondrial DNA depletion.
We studied five new patients with mitochondrial DNA (mtDNA) depletion to better define the clinical spectrum of this disorder. mtDNA depletion has been associated with myopathy or hepatopathy, or both, in infants and young children. Involvement of the CNS and peri... |
9,633,730 | eng | [
"D000236",
"Q000097",
"Q000150",
"Q000601",
"D000368",
"D000690",
"Q000150",
"Q000503",
"D002118",
"Q000097",
"D018450",
"D017809",
"D005260",
"D006801",
"D006961",
"Q000150",
"D008297",
"D008875",
"D018908",
"Q000503",
"D010281",
"Q000097",
"D010282",
"Q000097",
"Q00... | [
"Adenoma",
"Aged",
"Amyotrophic Lateral Sclerosis",
"Calcium",
"Disease Progression",
"Fatal Outcome",
"Female",
"Humans",
"Hyperparathyroidism",
"Male",
"Middle Aged",
"Muscle Weakness",
"Parathyroid Hormone",
"Parathyroid Neoplasms",
"Parathyroidectomy"
] | 1998 | Jun | Primary hyperparathyroidism and ALS: is there a relation?
An association between primary hyperparathyroidism (PHP) and amyotrophic lateral sclerosis (ALS) has been noted; however, a causal relation between these disorders has not been confirmed. We report five patients (three men, two women) meeting El Escorial criteri... |
9,633,731 | eng | [
"D000328",
"D000368",
"D000690",
"Q000175",
"Q000378",
"D001224",
"Q000031",
"Q000378",
"D005260",
"D006801",
"D008279",
"D009682",
"D008297",
"D008875",
"D009044",
"Q000378",
"D011712",
"Q000378",
"D012016",
"D014018"
] | [
"Adult",
"Aged",
"Amyotrophic Lateral Sclerosis",
"Aspartic Acid",
"Female",
"Humans",
"Magnetic Resonance Imaging",
"Magnetic Resonance Spectroscopy",
"Male",
"Middle Aged",
"Motor Cortex",
"Pyramidal Tracts",
"Reference Values",
"Tissue Distribution"
] | 1998 | Jun | Decreased N-acetylaspartate in motor cortex and corticospinal tract in ALS.
The primary objectives of this study were to test whether 1) N-acetylaspartate (NAA), a neuronal marker, is reduced in motor cortex and corticospinal-tract (CST) brain regions of ALS patients; and 2) motor cortex NAA correlates to a clinical me... |
9,633,732 | eng | [
"D000208",
"D000328",
"D000368",
"D000818",
"D001323",
"Q000032",
"D001327",
"Q000276",
"D001342",
"Q000150",
"Q000276",
"D005260",
"D006801",
"D008297",
"D008875",
"D009369",
"Q000150",
"D009422",
"Q000276",
"D009474",
"Q000276",
"D011233",
"D011863",
"Q000379",
"D05... | [
"Acute Disease",
"Adult",
"Aged",
"Animals",
"Autoantibodies",
"Autoimmune Diseases",
"Autonomic Nervous System Diseases",
"Female",
"Humans",
"Male",
"Middle Aged",
"Neoplasms",
"Nervous System Diseases",
"Neurons",
"Precipitin Tests",
"Radioimmunoassay",
"Rats",
"Receptors, Nicot... | 1998 | Jun | Neuronal nicotinic ACh receptor antibody in subacute autonomic neuropathy and cancer-related syndromes.
Autoantibodies specific for the acetylcholine receptor (AChR) of skeletal muscle (containing the alpha1 subunit) impair neuromuscular transmission in myasthenia gravis (MG). AChRs mediating fast synaptic transmission... |
9,633,733 | eng | [
"D015526",
"Q000145",
"Q000503",
"Q000523",
"D000328",
"D003071",
"Q000502",
"D018450",
"D005260",
"D015658",
"Q000209",
"D006801",
"D008297",
"D008875",
"D011597",
"Q000502",
"D012307",
"D015819",
"Q000150",
"D016019"
] | [
"AIDS Dementia Complex",
"Adult",
"Cognition",
"Disease Progression",
"Female",
"HIV Infections",
"Humans",
"Male",
"Middle Aged",
"Psychomotor Performance",
"Risk Factors",
"Substance Abuse, Intravenous",
"Survival Analysis"
] | 1998 | Jun | Variable progression of HIV-associated dementia.
A consecutive series of 71 patients diagnosed with HIV-associated dementia (HAD) (1984-1994) were studied to characterize the clinical course of HAD, and to identify predictive markers of rapid neurologic progression. Neurologic progression rate was determined from the c... |
9,633,734 | eng | [
"D000328",
"D019380",
"Q000627",
"D001810",
"Q000502",
"D002560",
"Q000502",
"D003072",
"Q000150",
"D006679",
"Q000150",
"Q000175",
"Q000188",
"Q000503",
"D006801",
"D008279",
"D008875",
"D010487",
"Q000098",
"D012016",
"D015215",
"Q000627"
] | [
"Adult",
"Anti-HIV Agents",
"Blood Volume",
"Cerebrovascular Circulation",
"Cognition Disorders",
"HIV Seropositivity",
"Humans",
"Magnetic Resonance Imaging",
"Middle Aged",
"Periaqueductal Gray",
"Reference Values",
"Zidovudine"
] | 1998 | Jun | Increased cerebral blood volume in HIV-positive patients detected by functional MRI.
To study changes in cerebral hemodynamics related to HIV infection. Cerebral injury is a well-known manifestation of HIV infection. Physiologic changes in the HIV brain may precede structural changes and may be detected by functional M... |
9,633,735 | eng | [
"D000328",
"D044467",
"Q000235",
"D000995",
"Q000627",
"D002170",
"D002494",
"Q000382",
"D015331",
"D016172",
"D005260",
"D014644",
"Q000235",
"D006801",
"D008297",
"D008581",
"Q000382",
"D009169",
"Q000235",
"Q000302",
"Q000472",
"D012150",
"D013045",
"D014376",
"Q00... | [
"Adult",
"American Indian or Alaska Native",
"Antitubercular Agents",
"Canada",
"Central Nervous System Infections",
"Cohort Studies",
"DNA Fingerprinting",
"Female",
"Genetic Variation",
"Humans",
"Male",
"Meningitis",
"Mycobacterium tuberculosis",
"Polymorphism, Restriction Fragment Leng... | 1998 | Jun | M. tuberculosis molecular variation in CNS infection: evidence for strain-dependent neurovirulence.
To determine the molecular diversity among Mycobacterium tuberculosis isolates associated with central nervous system tuberculosis (CNS TB) in a defined cohort of HIV uninfected patients. A retrospective analysis was per... |
9,633,736 | eng | [
"D000328",
"D001921",
"Q000473",
"D004185",
"D004305",
"D004311",
"D005260",
"D006801",
"D008279",
"D008297",
"D008775",
"Q000008",
"Q000009",
"Q000627",
"D009103",
"Q000175",
"Q000188",
"Q000503",
"D009333",
"D018696",
"Q000008",
"Q000009",
"Q000627",
"D012008",
"D01... | [
"Adult",
"Brain",
"Disability Evaluation",
"Dose-Response Relationship, Drug",
"Double-Blind Method",
"Female",
"Humans",
"Magnetic Resonance Imaging",
"Male",
"Methylprednisolone",
"Multiple Sclerosis",
"Neck",
"Neuroprotective Agents",
"Recurrence",
"Spinal Cord"
] | 1998 | Jun | Randomized trial comparing two different high doses of methylprednisolone in MS: a clinical and MRI study.
To assess the efficacy of two different high doses of intravenous methylprednisolone (IVMP) for the treatment of relapses in MS. IVMP is the treatment of choice for MS relapses, but it is unknown whether its effec... |
9,633,738 | eng | [
"D000203",
"D000328",
"D000368",
"D000369",
"D000701",
"Q000009",
"Q000627",
"D003929",
"Q000188",
"Q000503",
"D004311",
"D005260",
"D005500",
"D006801",
"D008297",
"D008875",
"D010146",
"Q000503",
"D010166",
"D011788",
"D012890",
"Q000502",
"D014147",
"Q000009",
"Q00... | [
"Activities of Daily Living",
"Adult",
"Aged",
"Aged, 80 and over",
"Analgesics, Opioid",
"Diabetic Neuropathies",
"Double-Blind Method",
"Female",
"Follow-Up Studies",
"Humans",
"Male",
"Middle Aged",
"Pain",
"Palliative Care",
"Quality of Life",
"Sleep",
"Tramadol"
] | 1998 | Jun | Double-blind randomized trial of tramadol for the treatment of the pain of diabetic neuropathy.
The objective of this study was to evaluate the efficacy and safety of tramadol in treating the pain of diabetic neuropathy. The pain of diabetic neuropathy is a major cause of morbidity among these patients and treatment, a... |
9,633,740 | eng | [
"D001921",
"Q000000981",
"Q000473",
"D002555",
"Q000502",
"D003560",
"Q000150",
"Q000503",
"Q000601",
"D004027",
"Q000503",
"D006801",
"D019585",
"Q000175",
"Q000209",
"D008279",
"D008297",
"D008875",
"D010523",
"Q000150",
"Q000503",
"Q000601",
"D011312",
"D012422",
"... | [
"Brain",
"Cerebrospinal Fluid",
"Cysts",
"Diencephalon",
"Humans",
"Intracranial Hypotension",
"Magnetic Resonance Imaging",
"Male",
"Middle Aged",
"Peripheral Nervous System Diseases",
"Pressure",
"Rupture, Spontaneous",
"Sleep Stages",
"Spinal Nerve Roots",
"Tomography, X-Ray Computed"... | 1998 | Jun | Spontaneous intracranial hypotension resulting in stupor caused by diencephalic compression.
A 51-year-old man had a 4-month history of progressive headache and gradual onset of somnolence. MRI suggested spontaneous intracranial hypotension (SIH) with diencephalic compression, but he did not improve after three epidura... |
9,633,739 | eng | [
"D049672",
"D049673",
"D006782",
"Q000266",
"Q000458",
"D006801",
"D009422",
"Q000266",
"Q000628",
"D009462",
"Q000266",
"D015143"
] | [
"History, 19th Century",
"History, 20th Century",
"Hospitals, Special",
"Humans",
"Nervous System Diseases",
"Neurology",
"Philadelphia"
] | 1998 | Jun | Philadelphia Infirmary for Nervous Diseases: America's original model of institutional neurology.
The role and contributions of the Philadelphia Orthopedic Hospital and Infirmary for Nervous Diseases in the development of neurology in 19th-century America are described. American neurology was largely born during the Ci... |
9,633,737 | eng | [
"D000368",
"D000701",
"Q000008",
"Q000009",
"Q000627",
"D018592",
"D003692",
"D004311",
"D005260",
"D006562",
"Q000150",
"D006801",
"D008297",
"D008875",
"D009437",
"Q000188",
"Q000503",
"Q000821",
"D010098",
"Q000008",
"Q000009",
"Q000627",
"D010146",
"Q000503",
"D01... | [
"Aged",
"Analgesics, Opioid",
"Cross-Over Studies",
"Delayed-Action Preparations",
"Double-Blind Method",
"Female",
"Herpes Zoster",
"Humans",
"Male",
"Middle Aged",
"Neuralgia",
"Oxycodone",
"Pain",
"Treatment Outcome"
] | 1998 | Jun | Efficacy of oxycodone in neuropathic pain: a randomized trial in postherpetic neuralgia.
Although opioid analgesics are used in the management of neuropathic pain syndromes, evidence of their efficacy remains to be established. We evaluated the clinical efficacy and safety of oxycodone in neuropathic pain using posther... |
9,633,741 | eng | [
"D000368",
"D002545",
"Q000188",
"D002305",
"Q000139",
"Q000000981",
"D002561",
"Q000188",
"D017809",
"D005260",
"D006801",
"D008875",
"D010490",
"Q000139",
"Q000000981",
"D010960",
"Q000009",
"Q000627",
"D011994",
"D015912",
"Q000009",
"D010959",
"Q000009",
"Q000627",
... | [
"Aged",
"Brain Ischemia",
"Cardiac Tamponade",
"Cerebrovascular Disorders",
"Fatal Outcome",
"Female",
"Humans",
"Middle Aged",
"Pericardial Effusion",
"Plasminogen Activators",
"Recombinant Proteins",
"Thrombolytic Therapy",
"Tissue Plasminogen Activator",
"Ultrasonography"
] | 1998 | Jun | Hemopericardium and cardiac tamponade after thrombolysis for acute ischemic stroke.
Hemorrhage is the major complication of IV recombinant tissue plasminogen activator (rt-PA) treatment for stroke. We report three patients with mild or indistinct cardiac symptoms prior to thrombolysis in whom hemodynamically significan... |
9,633,742 | eng | [
"D000368",
"D002545",
"Q000150",
"Q000175",
"D005158",
"Q000209",
"Q000503",
"D006801",
"D008279",
"D008280",
"D008297",
"D010812",
"D011149",
"Q000098",
"Q000473",
"D014836"
] | [
"Aged",
"Brain Ischemia",
"Facial Paralysis",
"Humans",
"Magnetic Resonance Imaging",
"Magnetics",
"Male",
"Physical Stimulation",
"Pons",
"Volition"
] | 1998 | Jun | Isolated voluntary facial paresis due to pontine ischemia.
We describe a patient with isolated voluntary facial paresis due to a unilateral lacunar lesion in the contralateral mediodorsal middle base of the pons. Transcranial magnetic stimulation confirmed the involvement of supranuclear corticofacial tract fibers and ... |
9,633,744 | eng | [
"D014695",
"D015170",
"Q000502",
"D006801",
"D008026",
"D008279",
"D008297",
"D008875",
"D009333",
"D013116",
"Q000473",
"Q000601",
"D013118",
"Q000175",
"Q000209",
"Q000503",
"D014057",
"D017287",
"Q000009"
] | [
"Cerebral Ventriculography",
"Cerebrospinal Fluid Pressure",
"Humans",
"Ligation",
"Magnetic Resonance Imaging",
"Male",
"Middle Aged",
"Neck",
"Spinal Cord",
"Spinal Cord Diseases",
"Tomography, X-Ray Computed",
"Ventriculoperitoneal Shunt"
] | 1998 | Jun | Upper cervical myelopathy associated with low CSF pressure: a complication of ventriculoperitoneal shunt.
A patient who had undergone ventriculoperitoneal shunting developed upper cervical myelopathy. His CSF pressure was markedly low, and deformation of the spinal cord and shrinkage of the subarachnoid space at the up... |
9,633,745 | eng | [
"D002535",
"Q000002",
"D002675",
"D003937",
"D005260",
"D006429",
"Q000151",
"Q000175",
"Q000209",
"D006801",
"D007223",
"D008279",
"D014057"
] | [
"Cerebral Aqueduct",
"Child, Preschool",
"Diagnosis, Differential",
"Female",
"Hemiplegia",
"Humans",
"Infant",
"Magnetic Resonance Imaging",
"Tomography, X-Ray Computed"
] | 1998 | Jun | Congenital bilateral perisylvian polymicrogyria presenting as congenital hemiplegia.
We report three children with pure congenital hemiplegia found to have congenital bilateral perisylvian polymicrogyria (CBPP). None of our patients had the seizures, oromotor dysfunction, or cognitive impairment usually associated with... |
9,633,746 | eng | [
"D000293",
"D002331",
"Q000097",
"Q000134",
"Q000652",
"D002648",
"D002675",
"D005260",
"D005334",
"Q000097",
"Q000134",
"Q000652",
"D005759",
"Q000097",
"Q000134",
"Q000652",
"D006801",
"D007223",
"D007231",
"D008297",
"D016920",
"Q000097",
"Q000134",
"Q000652",
"D00... | [
"Adolescent",
"Carnitine",
"Child",
"Child, Preschool",
"Female",
"Fever",
"Gastroenteritis",
"Humans",
"Infant",
"Infant, Newborn",
"Male",
"Meningitis, Bacterial",
"Nervous System Diseases",
"Osmolar Concentration",
"Reference Values",
"Seizures"
] | 1998 | Jun | CSF levels of carnitine in children with meningitis, neurologic disorders, acute gastroenteritis, and seizure.
Carnitine concentrations in CSF, serum, and urine in normal febrile children and children with meningitis, neurologic disorders, and dehydration were studied. Carnitine levels in CSF were 1/10 compared with se... |
9,633,747 | eng | [
"D000368",
"D016913",
"D001026",
"D007562",
"Q000209",
"D006801",
"D007430",
"D008297",
"D011183",
"D012709",
"Q000627"
] | [
"Aged",
"Blood Component Transfusion",
"Coronary Artery Bypass",
"Creutzfeldt-Jakob Syndrome",
"Humans",
"Intraoperative Care",
"Male",
"Postoperative Complications",
"Serum Albumin"
] | 1998 | Jun | Creutzfeldt-Jakob disease (CJD) after blood product transfusion from a donor with CJD.
We report a second case of an association between an albumin transfusion and Creutzfeldt-Jakob disease. On balance, we believe our case represents a chance and not a causal relation. |
9,633,748 | eng | [
"D001927",
"Q000139",
"Q000503",
"D002444",
"Q000008",
"Q000009",
"D002511",
"Q000008",
"Q000009",
"D062787",
"D004409",
"Q000503",
"D005260",
"D006801",
"D008297",
"D008875",
"D009207",
"Q000139",
"D012894",
"Q000502"
] | [
"Brain Diseases",
"Cefuroxime",
"Cephalosporins",
"Drug Overdose",
"Dyskinesia, Drug-Induced",
"Female",
"Humans",
"Male",
"Middle Aged",
"Myoclonus",
"Sleep Stages"
] | 1998 | Jun | Cefuroxime-induced encephalopathy.
We describe four patients who developed an encephalopathic syndrome characterized by obtundation or stupor, myoclonic jerks, and asterixis in association with cefuroxime therapy. Three patients had renal failure. These cases suggest that cefuroxime in overdose or in conventional doses... |
9,633,749 | eng | [
"D000328",
"D001483",
"D002319",
"Q000503",
"D004272",
"Q000235",
"D017079",
"Q000502",
"D005260",
"D006801",
"D008969",
"D015394",
"D009132",
"Q000473",
"D009136",
"Q000235",
"Q000473",
"Q000503",
"D009154",
"Q000235",
"D009420",
"Q000503",
"D016133",
"D012150",
"D01... | [
"Adult",
"Base Sequence",
"Cardiovascular System",
"DNA, Mitochondrial",
"Exercise Tolerance",
"Female",
"Humans",
"Molecular Sequence Data",
"Molecular Structure",
"Muscles",
"Muscular Dystrophies",
"Mutation",
"Nervous System",
"Polymerase Chain Reaction",
"Polymorphism, Restriction Fr... | 1998 | Jun | A new mitochondrial tRNA(Met) gene mutation in a patient with dystrophic muscle and exercise intolerance.
A 30-year-old woman with a novel heteroplasmic U4409C mtDNA mutation in the tRNA(Met) gene presented with growth retardation, muscle weakness, severe exercise intolerance, and lactic acidosis. Muscle biopsy showed ... |
9,633,750 | eng | [
"D000293",
"D000690",
"Q000175",
"D001921",
"Q000473",
"D006801",
"D008279",
"D008297",
"D011712",
"Q000473",
"D012016"
] | [
"Adolescent",
"Amyotrophic Lateral Sclerosis",
"Brain",
"Humans",
"Magnetic Resonance Imaging",
"Male",
"Pyramidal Tracts",
"Reference Values"
] | 1998 | Jun | MRI in juvenile ALS: a patient report.
We describe the MR images of a patient with juvenile ALS. MRI of the brain showed bilateral hyperintensities along the corticospinal tracts extending from the corona radiata to the brainstem on T2-weighted images. These findings should be differentiated from the slight hyperintens... |
9,633,751 | eng | [
"D000368",
"D001921",
"Q000473",
"D003937",
"D004568",
"D004576",
"D005260",
"D006801",
"D008279",
"D011602",
"Q000175",
"D014202",
"Q000175"
] | [
"Aged",
"Brain",
"Diagnosis, Differential",
"Electrodiagnosis",
"Electromyography",
"Female",
"Humans",
"Magnetic Resonance Imaging",
"Psychophysiologic Disorders",
"Tremor"
] | 1998 | Jun | Electrophysiological aids in distinguishing organic from psychogenic tremor.
The clinical differentiation of tremors of organic and psychogenic origin can be difficult. We describe a patient with unilateral upper limb tremor that was initially considered to have a psychogenic cause, but subsequent frequency analysis of... |
9,633,752 | eng | [
"D000978",
"Q000627",
"D004581",
"D006801",
"D007854",
"Q000009",
"D008297",
"D008875",
"D016273",
"D010300",
"Q000188",
"Q000453",
"D011177",
"D015995"
] | [
"Antiparkinson Agents",
"Electronics",
"Humans",
"Lead",
"Male",
"Middle Aged",
"Occupational Exposure",
"Parkinson Disease",
"Postal Service",
"Prevalence"
] | 1998 | Jun | High prevalence of parkinsonism after occupational exposure to lead-sulfate batteries.
Seven of nine postal workers exposed to lead-sulfate batteries over a period of up to 30 years developed parkinsonian symptoms. One of the remaining two showed left-hand bradykinesia and one was not available for examination. The hig... |
9,633,753 | eng | [
"D000328",
"D001483",
"D001921",
"Q000473",
"D001933",
"Q000473",
"D005260",
"D006801",
"D008279",
"D008297",
"D008875",
"D012091",
"D013132",
"Q000175",
"Q000235",
"D013788",
"Q000473"
] | [
"Adult",
"Base Sequence",
"Brain",
"Brain Stem",
"Female",
"Humans",
"Magnetic Resonance Imaging",
"Male",
"Middle Aged",
"Repetitive Sequences, Nucleic Acid",
"Spinocerebellar Degenerations",
"Thalamus"
] | 1998 | Jun | The brainstem and thalamic lesions in dentatorubral-pallidoluysian atrophy: an MRI study.
We studied the frequency and characteristics of brainstem and thalamic lesions in dentatorubral-pallidoluysian atrophy using MRI. Of 15 subjects diagnosed by DNA analysis, 13 had lesions in the pontine base, nine in the midbrain, ... |
9,633,754 | eng | [
"D000339",
"Q000187",
"D000978",
"Q000627",
"D004305",
"D005260",
"D006801",
"D007262",
"D007980",
"Q000627",
"D008297",
"D008875",
"D010300",
"Q000188",
"Q000523",
"D012647"
] | [
"Affect",
"Antiparkinson Agents",
"Dose-Response Relationship, Drug",
"Female",
"Humans",
"Infusions, Intravenous",
"Levodopa",
"Male",
"Middle Aged",
"Parkinson Disease",
"Self-Assessment"
] | 1998 | Jun | Mood response to levodopa infusion in early Parkinson's disease.
Mood response to levodopa infusion was studied in 18 Parkinson's disease (PD) patients during the first year of levodopa therapy before and after 2-hour (1.0 mg/kg/h) levodopa infusions at baseline and 6- and 12-month follow-up. Mood elevation was greates... |
9,633,755 | eng | [
"D000293",
"D000328",
"D002648",
"D005133",
"Q000502",
"D005260",
"D006801",
"D019586",
"Q000150",
"D008279",
"D008297",
"D015835",
"Q000209",
"Q000503",
"D012851",
"Q000150",
"Q000175"
] | [
"Adolescent",
"Adult",
"Child",
"Eye Movements",
"Female",
"Humans",
"Intracranial Hypertension",
"Magnetic Resonance Imaging",
"Male",
"Ocular Motility Disorders",
"Sinus Thrombosis, Intracranial"
] | 1998 | Jun | Unusual ocular motility disturbances with increased intracranial pressure.
We evaluated nine patients with external ophthalmoparesis and increased intracranial pressure. The eye movements normalized when the intracranial pressure was controlled. Investigations for an underlying cause of elevated cerebrospinal fluid pre... |
9,633,756 | eng | [
"D000328",
"D005240",
"D005260",
"D006801",
"D008279",
"D008297",
"D009902",
"Q000175",
"Q000503",
"D010775",
"D010865",
"D015349",
"Q000502",
"D014785",
"Q000502"
] | [
"Adult",
"Feasibility Studies",
"Female",
"Humans",
"Magnetic Resonance Imaging",
"Male",
"Optic Neuritis",
"Photic Stimulation",
"Pilot Projects",
"Vision, Monocular",
"Vision, Ocular"
] | 1998 | Jun | Visual activation patterns in patients with optic neuritis: an fMRI pilot study.
We studied the use of functional MRI (fMRI) with visual stimulation in nine patients with unilateral optic neuritis. Eight healthy subjects served as controls. Patients showed reduced activation upon stimulation of the affected eye, on ave... |
9,633,757 | eng | [
"D000975",
"Q000627",
"D000978",
"Q000627",
"D004305",
"D004311",
"D006801",
"D010300",
"Q000188",
"D012642",
"Q000627",
"D014810",
"Q000008",
"Q000134",
"Q000627"
] | [
"Antioxidants",
"Antiparkinson Agents",
"Dose-Response Relationship, Drug",
"Double-Blind Method",
"Humans",
"Parkinson Disease",
"Selegiline",
"Vitamin E"
] | 1998 | Jun | Alpha tocopherol in CSF of subjects taking high-dose vitamin E in the DATATOP study. Parkinson Study Group.
Alpha-Tocopherol concentrations were determined in the CSF of patients with early untreated Parkinson's disease receiving 2,000 IU vitamin E orally per day. After treatment the concentrations increased significan... |
9,633,758 | eng | [
"D000368",
"D001288",
"Q000502",
"D002561",
"Q000503",
"D007839",
"Q000502",
"D006801",
"D013577"
] | [
"Aged",
"Attention",
"Cerebrovascular Disorders",
"Functional Laterality",
"Humans",
"Syndrome"
] | 1998 | Jun | Unilateral neglect: a common but heterogeneous syndrome.
The neglect syndrome is a cluster of neurologic symptoms commonly found after right hemisphere damage. This study investigates the degree of association between the main components in a representative sample of 69 patients at 2 to 3 days poststroke. Despite evide... |
9,633,760 | eng | [
"D000328",
"D000368",
"D000690",
"Q000175",
"Q000503",
"D004558",
"D004568",
"D005260",
"D006801",
"D008297",
"D008875",
"D016472",
"Q000175",
"Q000503",
"D009431",
"Q000502",
"D013126",
"Q000503"
] | [
"Adult",
"Aged",
"Amyotrophic Lateral Sclerosis",
"Electric Stimulation",
"Electrodiagnosis",
"Female",
"Humans",
"Male",
"Middle Aged",
"Motor Neuron Disease",
"Neural Conduction",
"Spinal Nerve Roots"
] | 1998 | Jun | Root stimulation studies in the evaluation of patients with motor neuron disease.
Nerve root stimulation may be employed in patients with motor neuron disease (MND) to rule out motor neuropathy with conduction block. The diagnostic utility of these studies is unknown, in part because the range of amplitude changes acro... |
9,633,759 | eng | [
"D000293",
"D000328",
"D000368",
"D000369",
"D000375",
"Q000502",
"D000483",
"D000544",
"Q000235",
"D001057",
"Q000235",
"D002648",
"D005091",
"Q000235",
"D005787",
"D005838",
"D006801",
"D026503",
"D008875",
"D011110",
"Q000235",
"D011971",
"Q000235"
] | [
"Adolescent",
"Adult",
"Aged",
"Aged, 80 and over",
"Aging",
"Alleles",
"Alzheimer Disease",
"Apolipoproteins E",
"Child",
"Exons",
"Gene Frequency",
"Genotype",
"Humans",
"Low Density Lipoprotein Receptor-Related Protein-1",
"Middle Aged",
"Polymorphism, Genetic",
"Receptors, Immuno... | 1998 | Jun | Confirmation of an association between a polymorphism in exon 3 of the low-density lipoprotein receptor-related protein gene and Alzheimer's disease.
C766T, a polymorphism in exon 3 of the gene for the low-density lipoprotein receptor-related protein (LRP), was found to be associated with late-onset Alzheimer's disease... |
9,633,761 | eng | [
"D000082",
"Q000627",
"D000276",
"Q000627",
"D000328",
"D018712",
"Q000627",
"D004305",
"D004359",
"D005260",
"D005938",
"Q000008",
"Q000627",
"D006801",
"D007251",
"Q000188",
"Q000503",
"D000068556",
"D000068576",
"D016899",
"Q000627",
"D008297",
"D009103",
"Q000188",
... | [
"Acetaminophen",
"Adjuvants, Immunologic",
"Adult",
"Analgesics, Non-Narcotic",
"Dose-Response Relationship, Drug",
"Drug Therapy, Combination",
"Female",
"Glucocorticoids",
"Humans",
"Influenza, Human",
"Interferon beta-1a",
"Interferon beta-1b",
"Interferon-beta",
"Male",
"Multiple Scl... | 1998 | Jun | Low-dose steroids reduce flu-like symptoms at the initiation of IFNbeta-1b in relapsing-remitting MS.
To determine whether low-dose prednisone reduces flu-like symptoms at the initiation of interferon beta 1-b (IFNbeta-1b), we studied 71 patients with clinically definite, relapsing-remitting multiple sclerosis who were... |
9,633,762 | eng | [
"D000050",
"Q000473",
"D000328",
"D001055",
"Q000097",
"D002819",
"Q000097",
"Q000150",
"Q000175",
"D005260",
"D019788",
"D006402",
"Q000150",
"D006801",
"D008279",
"D019275",
"D014055"
] | [
"Acanthocytes",
"Adult",
"Apolipoproteins B",
"Chorea",
"Female",
"Fluorodeoxyglucose F18",
"Hematologic Diseases",
"Humans",
"Magnetic Resonance Imaging",
"Radiopharmaceuticals",
"Tomography, Emission-Computed"
] | 1998 | Jun | Neuroacanthocytosis and aprebetalipoproteinemia.
A 30-year-old woman presented with a progressive neurologic disorder characterized by seizures, buccolingual dyskinesias, orofacial tics, choreiform movements, atrophy, and areflexia. Investigations revealed normal lipid profile except for aprebetalipoproteinemia. Phase-... |
9,633,763 | eng | [
"D000328",
"D002533",
"D002560",
"Q000502",
"D018450",
"D005150",
"Q000150",
"Q000175",
"Q000503",
"D006429",
"Q000209",
"D006801",
"D008279",
"D008297",
"D008881",
"Q000209",
"D014666",
"Q000503"
] | [
"Adult",
"Cerebral Angiography",
"Cerebrovascular Circulation",
"Disease Progression",
"Facial Hemiatrophy",
"Hemiplegia",
"Humans",
"Magnetic Resonance Imaging",
"Male",
"Migraine Disorders",
"Vasomotor System"
] | 1998 | Jun | Progressive facial hemiatrophy: abnormality of intracranial vasculature.
Progressive facial hemiatrophy (PFH) or Parry-Romberg syndrome is associated with ipsilateral brain lesions and neurologic symptoms. We describe a 35-year-old man with PFH and frequent hemiplegic migraine. On cerebral angiography, reversible vesse... |
9,633,786 | eng | [
"D000375",
"Q000502",
"D001794",
"Q000502",
"D018660",
"D006332",
"Q000473",
"Q000503",
"D002940",
"Q000502",
"D005260",
"D006352",
"D006801",
"D006973",
"Q000473",
"Q000503",
"D008297",
"D008875",
"D009206",
"Q000473",
"D012727"
] | [
"Aging",
"Blood Pressure",
"Blood Pressure Monitoring, Ambulatory",
"Cardiomegaly",
"Circadian Rhythm",
"Female",
"Heart Ventricles",
"Humans",
"Hypertension",
"Male",
"Middle Aged",
"Myocardium",
"Sex Characteristics"
] | 1998 | May | Lack of association between blood pressure variability and left ventricular mass in essential hypertension.
Blood pressure (BP) variability could induce detrimental effects on left ventricular (LV) structure in hypertension. We investigated the association between short-term BP variability, assessed with 24-h noninvasi... |
9,633,787 | eng | [
"D000328",
"D017704",
"Q000502",
"D005260",
"D006339",
"Q000502",
"D006801",
"D006973",
"Q000503",
"D007333",
"D008297",
"D008875",
"D012016",
"D012044",
"D013577"
] | [
"Adult",
"Baroreflex",
"Female",
"Heart Rate",
"Humans",
"Hypertension",
"Insulin Resistance",
"Male",
"Middle Aged",
"Reference Values",
"Regression Analysis",
"Syndrome"
] | 1998 | May | Heart rate variability and baroreflex sensitivity in hypertensive subjects with and without metabolic features of insulin resistance syndrome.
Both abnormal autonomic control of heart rate, assessed by heart rate variability (HRV) and baroreflex sensitivity (BRS), and insulin resistance syndrome are common in hypertens... |
9,633,788 | eng | [
"D000328",
"D000375",
"Q000502",
"D001794",
"Q000502",
"D002940",
"Q000502",
"D019314",
"Q000097",
"D005260",
"D006801",
"D006973",
"Q000097",
"Q000503",
"Q000628",
"D008297",
"D008875",
"D012016",
"D012727"
] | [
"Adult",
"Aging",
"Blood Pressure",
"Circadian Rhythm",
"Dehydroepiandrosterone Sulfate",
"Female",
"Humans",
"Hypertension",
"Male",
"Middle Aged",
"Reference Values",
"Sex Characteristics"
] | 1998 | May | Relationship between blood pressure variability and serum dehydroepiandrosterone sulfate levels.
Decreased diurnal blood pressure variability and low dehydroepiandrosterone sulfate (DHEAS) levels are important predictors of cardiovascular morbidity and mortality. The aim of the study was to determine the relationship b... |
9,633,789 | eng | [
"D000293",
"D000328",
"D000375",
"Q000502",
"D017704",
"Q000502",
"D001794",
"Q000502",
"D002940",
"Q000502",
"D003971",
"D005260",
"D006339",
"Q000502",
"D006728",
"Q000097",
"D006801",
"D008297",
"D008991",
"D013599",
"D013997",
"D017086",
"Q000097",
"Q000503"
] | [
"Adolescent",
"Adult",
"Aging",
"Baroreflex",
"Blood Pressure",
"Circadian Rhythm",
"Diastole",
"Female",
"Heart Rate",
"Hormones",
"Humans",
"Male",
"Monitoring, Physiologic",
"Systole",
"Time Factors",
"beta-Thalassemia"
] | 1998 | May | Blood pressure and heart rate in young thalassemia major patients.
The analysis of blood pressure (BP) and heart rate (HR) variability is currently used to investigate the mechanisms responsible for cardiovascular control; therefore, we assessed whether an impairment of 24-h BP and HR profiles and sympathovagal interac... |
9,633,790 | eng | [
"D000328",
"D057911",
"D000959",
"Q000627",
"D002908",
"D016232",
"Q000097",
"D005260",
"D006133",
"Q000097",
"D006352",
"D006801",
"D006973",
"Q000188",
"D019808",
"Q000627",
"D008297",
"D009206",
"Q000473"
] | [
"Adult",
"Angiotensin Receptor Antagonists",
"Antihypertensive Agents",
"Chronic Disease",
"Endothelins",
"Female",
"Growth Substances",
"Heart Ventricles",
"Humans",
"Hypertension",
"Losartan",
"Male",
"Myocardium"
] | 1998 | May | Changes of plasma endothelin and growth factor levels, and of left ventricular mass, after chronic AT1-receptor blockade in human hypertension.
The stimulation of autocrine and paracrine factors such as basic fibroblast- (bFGF) and platelet-derived (PDGF) growth factors mediates many of the growth-promoting actions of ... |
9,633,792 | eng | [
"D000818",
"D001835",
"Q000502",
"D002199",
"Q000502",
"D004396",
"D005070",
"D005632",
"D006973",
"Q000139",
"Q000503",
"D007333",
"D008297",
"D008833",
"Q000502",
"D051381",
"D017207",
"D012709",
"Q000493"
] | [
"Animals",
"Body Weight",
"Capillary Permeability",
"Coloring Agents",
"Evans Blue",
"Fructose",
"Hypertension",
"Insulin Resistance",
"Male",
"Microcirculation",
"Rats",
"Rats, Sprague-Dawley",
"Serum Albumin"
] | 1998 | May | Reduction of capillary permeability in the fructose-induced hypertensive rat.
Impaired insulin transcapillary transport and the subsequent decrease in insulin delivery to target organs have been suggested to play a role in insulin resistance. These defects were studied in fructose-fed rats, an animal model with insulin... |
9,633,791 | eng | [
"D000818",
"D001158",
"Q000187",
"Q000473",
"D000077868",
"D001794",
"Q000187",
"D003900",
"D065128",
"D006973",
"Q000139",
"Q000378",
"Q000473",
"D010666",
"Q000494",
"D011743",
"Q000494",
"D011759",
"Q000494",
"D051381",
"D017207",
"D044022",
"D012965",
"D013997"
] | [
"Animals",
"Arteries",
"Atrasentan",
"Blood Pressure",
"Desoxycorticosterone",
"Endothelin Receptor Antagonists",
"Hypertension",
"Phenylpropionates",
"Pyrimidines",
"Pyrrolidines",
"Rats",
"Rats, Sprague-Dawley",
"Receptor, Endothelin A",
"Sodium Chloride",
"Time Factors"
] | 1998 | May | Effect of chronic treatment with two different ET(A) selective endothelin receptor antagonists on blood pressure and small artery structure of deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
Chronic treatment with a combined ET(A) and ET(B) endothelin receptor antagonist blunts hypertension development and s... |
9,633,793 | eng | [
"D000803",
"Q000097",
"Q000378",
"D000804",
"Q000031",
"Q000097",
"Q000493",
"Q000494",
"D000818",
"D000959",
"Q000494",
"D001794",
"Q000187",
"D007668",
"Q000378",
"D019808",
"Q000494",
"D008297",
"D051381",
"D017207",
"D011945",
"Q000502",
"D012083",
"Q000097"
] | [
"Angiotensin I",
"Angiotensin II",
"Animals",
"Antihypertensive Agents",
"Blood Pressure",
"Kidney",
"Losartan",
"Male",
"Rats",
"Rats, Sprague-Dawley",
"Receptors, Angiotensin",
"Renin"
] | 1998 | May | Renal uptake of circulating angiotensin II in Val5-angiotensin II infused rats is mediated by AT1 receptor.
Previous studies have demonstrated that augmentation of intrarenal angiotensin II (ANG II) levels during ANG II induced hypertension involves both endogenous formation and accumulation of circulating ANG II. The ... |
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Dataset Card for Pubmedabstracts
This dataset was created by: NCBI.
The abstracts in this datasets are obtained from NCBI, and includes everything up until September 2025.
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Citation Information
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